Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8ZHH3

- PGK_YERPE

UniProt

Q8ZHH3 - PGK_YERPE

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei36 – 361SubstrateUniRule annotation
    Binding sitei113 – 1131SubstrateUniRule annotation
    Binding sitei146 – 1461SubstrateUniRule annotation
    Binding sitei197 – 1971ATPUniRule annotation
    Binding sitei314 – 3141ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi340 – 3434ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-906-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:YPO0921, y3308, YP_3519
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 387387Phosphoglycerate kinasePRO_0000146047Add
    BLAST

    Proteomic databases

    PRIDEiQ8ZHH3.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    IntActiQ8ZHH3. 2 interactions.
    STRINGi214092.YPO0921.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZHH3.
    SMRiQ8ZHH3. Positions 2-387.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni21 – 233Substrate bindingUniRule annotation
    Regioni59 – 624Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiAGHPVGK.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZHH3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVIKMTDLD LAGKRVLIRA DLNVPVKEGK VTSDARIRAS LPTIEAALKQ    50
    GAKVMVTSHL GRPTEGEYNE EFSLLPVVNY LKEKLSSPVR LAKDYLDGVE 100
    IAAGELVVLE NVRFNKGEKK DDEALSKKYA ALCDVYVMDA FGTAHRAQAS 150
    THGVGKFAPI ACAGPLLSAE LEALGKALGN PARPMVAIVG GSKVSTKLTV 200
    LGALSKIADK LIVGGGIANT FVAAQGHNVG KSLYEADLIP EAKRLLETCD 250
    IPVPTDVRVA TEFSETAAAT LKPANEIKDD EQILDLGDES AERLAEILKN 300
    AKTILWNGPV GVFEFPNFRK GTEIVARAIA ESEAFSIAGG GDTLAAIDLF 350
    GIADQISYIS TGGGAFLEFV EGKKLPAVVM LEERAKQ 387
    Length:387
    Mass (Da):41,074
    Last modified:March 1, 2002 - v1
    Checksum:iB71E0BCD711C7A5D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL19588.1.
    AE009952 Genomic DNA. Translation: AAM86858.1.
    AE017042 Genomic DNA. Translation: AAS63673.1.
    PIRiAB0113.
    RefSeqiNP_670607.1. NC_004088.1.
    NP_994796.1. NC_005810.1.
    YP_002345969.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM86858; AAM86858; y3308.
    AAS63673; AAS63673; YP_3519.
    GeneIDi1148255.
    1173758.
    2763825.
    KEGGiype:YPO0921.
    ypk:y3308.
    ypm:YP_3519.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL19588.1 .
    AE009952 Genomic DNA. Translation: AAM86858.1 .
    AE017042 Genomic DNA. Translation: AAS63673.1 .
    PIRi AB0113.
    RefSeqi NP_670607.1. NC_004088.1.
    NP_994796.1. NC_005810.1.
    YP_002345969.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZHH3.
    SMRi Q8ZHH3. Positions 2-387.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8ZHH3. 2 interactions.
    STRINGi 214092.YPO0921.

    Proteomic databases

    PRIDEi Q8ZHH3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM86858 ; AAM86858 ; y3308 .
    AAS63673 ; AAS63673 ; YP_3519 .
    GeneIDi 1148255.
    1173758.
    2763825.
    KEGGi ype:YPO0921.
    ypk:y3308.
    ypm:YP_3519.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi AGHPVGK.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci YPES214092:GKDD-906-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiPGK_YERPE
    AccessioniPrimary (citable) accession number: Q8ZHH3
    Secondary accession number(s): Q0WIB9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 27, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3