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Protein

Glutaminase 1

Gene

glsA1

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei161SubstrateUniRule annotation1
Binding sitei168SubstrateUniRule annotation1
Binding sitei192SubstrateUniRule annotation1
Binding sitei244SubstrateUniRule annotation1
Binding sitei262Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 1UniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsA1UniRule annotation
Ordered Locus Names:YPO0949, y3336, YP_3492
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001106331 – 308Glutaminase 1Add BLAST308

Proteomic databases

PaxDbiQ8ZHF1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

IntActiQ8ZHF1, 5 interactors
STRINGi187410.y3336

Structurei

3D structure databases

ProteinModelPortaliQ8ZHF1
SMRiQ8ZHF1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiEPSGNPF

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZHF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTTLDNALL NDILQQVRPL IGQGKVADYI PALAEVPANK LGIAVCTLDG
60 70 80 90 100
QIFQAGDADE RFSIQSISKV LSLTLALSRY SEQDIWQRVG KEPSGQPFNS
110 120 130 140 150
LVQLELEKGK PRNPFINLGA LVVCDMLQSR LSAPKQRLLE VVRQLVKDDS
160 170 180 190 200
ISYDPRVARS EFEHSDRNAA IAYLMKSFGN FDNDVLTVLQ TYFHYCAMRM
210 220 230 240 250
SCVELARCFV YLANQGRSIS GSESLITPMQ ARQINALMIT SGMYDGAGEF
260 270 280 290 300
AFRVGMPGKS GVGGGIIAIV PDEFCIAVWS PELDHAGNSL AGTAALERLA

QQMGRSIF
Length:308
Mass (Da):33,700
Last modified:March 1, 2002 - v1
Checksum:iD80AD7C77F23FEC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL19615.1
AE009952 Genomic DNA Translation: AAM86886.1
AE017042 Genomic DNA Translation: AAS63647.1
PIRiAE0116
RefSeqiWP_002209989.1, NZ_PDBR01000033.1
YP_002345995.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM86886; AAM86886; y3336
AAS63647; AAS63647; YP_3492
GeneIDi1173785
KEGGiype:YPO0949
ypk:y3336
ypm:YP_3492
PATRICifig|214092.21.peg.1228

Similar proteinsi

Entry informationi

Entry nameiGLSA1_YERPE
AccessioniPrimary (citable) accession number: Q8ZHF1
Secondary accession number(s): Q0WI93
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health