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Q8ZGX4

- 6PGL_YERPE

UniProt

Q8ZGX4 - 6PGL_YERPE

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolism

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-1144-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
    Short name:
    6-P-gluconolactonaseUniRule annotation
    Gene namesi
    Name:pglUniRule annotation
    Ordered Locus Names:YPO1149, y3033, YP_1011
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 3343346-phosphogluconolactonasePRO_0000171142Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiQ8ZGX4. 7 interactions.
    STRINGi214092.YPO1149.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZGX4.
    SMRiQ8ZGX4. Positions 1-329.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cycloisomerase 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2706.
    HOGENOMiHOG000257418.
    KOiK07404.
    OMAiPMVIAPN.
    OrthoDBiEOG615VK7.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    HAMAPiMF_01605. 6P_gluconolactonase.
    InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view]
    PfamiPF10282. Lactonase. 1 hit.
    [Graphical view]
    SUPFAMiSSF50974. SSF50974. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8ZGX4-1 [UniParc]FASTAAdd to Basket

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    MKQAVYVASP DSQQIHVWQL DSAGELTLLQ TVDVPGQVQP MAISPNQRHL    50
    YVGVRPDFGI VSYHIADDGT LTAAGMAPLP GSPTHIDTDR QGRFLFSASY 100
    SFNCVSISPI DTHGVVQAPI QQLDDLPAPH SANIDPTNQI LLVPCLKEDK 150
    VRLFDLSAEG QLTPHAQADI TVAAGAGPRH MAFHPNHQVA YCVNELNSSV 200
    DVYQISNNGQ EYHLVQSLDA MPADFTGTRW AADIHITPNG RYLYISDRTA 250
    NLLGIFTVSE DGRVISLVGH HLTEAQPRGF NIDHSGNFLI ASGQKSDHIE 300
    VYRIDQNTGE LTTLKRYPVG KGPMWVSIRG AQNS 334
    Length:334
    Mass (Da):36,446
    Last modified:March 1, 2002 - v1
    Checksum:i4BDAC511EF8E0F06
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL19813.1.
    AE009952 Genomic DNA. Translation: AAM86584.1.
    AE017042 Genomic DNA. Translation: AAS61262.1.
    PIRiAC0141.
    RefSeqiNP_670333.1. NC_004088.1.
    NP_992385.1. NC_005810.1.
    YP_002346188.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM86584; AAM86584; y3033.
    AAS61262; AAS61262; YP_1011.
    GeneIDi1147980.
    1173998.
    2764787.
    KEGGiype:YPO1149.
    ypk:y3033.
    ypm:YP_1011.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL19813.1 .
    AE009952 Genomic DNA. Translation: AAM86584.1 .
    AE017042 Genomic DNA. Translation: AAS61262.1 .
    PIRi AC0141.
    RefSeqi NP_670333.1. NC_004088.1.
    NP_992385.1. NC_005810.1.
    YP_002346188.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZGX4.
    SMRi Q8ZGX4. Positions 1-329.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8ZGX4. 7 interactions.
    STRINGi 214092.YPO1149.

    Protocols and materials databases

    DNASUi 1147980.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM86584 ; AAM86584 ; y3033 .
    AAS61262 ; AAS61262 ; YP_1011 .
    GeneIDi 1147980.
    1173998.
    2764787.
    KEGGi ype:YPO1149.
    ypk:y3033.
    ypm:YP_1011.

    Phylogenomic databases

    eggNOGi COG2706.
    HOGENOMi HOG000257418.
    KOi K07404.
    OMAi PMVIAPN.
    OrthoDBi EOG615VK7.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci YPES214092:GKDD-1144-MONOMER.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    HAMAPi MF_01605. 6P_gluconolactonase.
    InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view ]
    Pfami PF10282. Lactonase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50974. SSF50974. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry namei6PGL_YERPE
    AccessioniPrimary (citable) accession number: Q8ZGX4
    Secondary accession number(s): Q0WHQ0, Q74W78, Q7CH64
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2005
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3