Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8ZF73

- DCYD_YERPE

UniProt

Q8ZF73 - DCYD_YERPE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

D-cysteine desulfhydrase

Gene

dcyD

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.UniRule annotation

Catalytic activityi

D-cysteine + H2O = H2S + NH3 + pyruvate.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. D-cysteine desulfhydrase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-amino acid metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciYPES214092:GKDD-1819-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
D-cysteine desulfhydraseUniRule annotation (EC:4.4.1.15UniRule annotation)
Gene namesi
Name:dcyDUniRule annotation
Synonyms:acd
Ordered Locus Names:YPO1845, y2462, YP_1548
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 330330D-cysteine desulfhydrasePRO_0000184519Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei52 – 521N6-(pyridoxal phosphate)lysineUniRule annotation

Proteomic databases

PRIDEiQ8ZF73.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi214092.YPO1845.

Structurei

3D structure databases

ProteinModelPortaliQ8ZF73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ACC deaminase/D-cysteine desulfhydrase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2515.
HOGENOMiHOG000022459.
KOiK05396.
OMAiIMAQSFE.
OrthoDBiEOG6FBX0P.

Family and domain databases

HAMAPiMF_01045. D_Cys_desulfhydr.
InterProiIPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR023702. D_Cys_desulphydr_bac.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PfamiPF00291. PALP. 1 hit.
[Graphical view]
PIRSFiPIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR01275. ACC_deam_rel. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZF73-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTLQQKLTQF PRLDLVGNAT PLEKLSRLSD YLGREIYIKR DDVTPVALGG
60 70 80 90 100
NKLRKLEFLA ADALRQGADT LVTAGAIQSN HVRQTAAVAA KLGLHCVALL
110 120 130 140 150
ENPIGTEQAN YLTNGNRLLL DLFNVDVVMC EALNDPNQQL AELATRVEAQ
160 170 180 190 200
GFRPYVVPIG GSNALGALGY VQCSLEIAAQ AAGNVAFSSV VVASGSAGTH
210 220 230 240 250
AGLAVGLQQL LPDAELIGVT VSRSADEQRP KVAQIQQALA TSLGMTDPLA
260 270 280 290 300
KITLWDSYFA PQYGMPNEEG IAAIKLLARL EGILLDPVYT GKAMAGLLDG
310 320 330
IEQQKFCDKG PILFIHTGGA PALFAYHPQV
Length:330
Mass (Da):35,039
Last modified:March 1, 2002 - v1
Checksum:iCDC974B8DBF26922
GO

Sequence cautioni

The sequence AAM86019.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL20485.1.
AE009952 Genomic DNA. Translation: AAM86019.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS61783.1.
PIRiAB0225.
RefSeqiNP_992906.1. NC_005810.1.
YP_002346839.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM86019; AAM86019; y2462.
AAS61783; AAS61783; YP_1548.
GeneIDi1174680.
2764100.
KEGGiype:YPO1845.
ypm:YP_1548.
PATRICi18593206. VBIYerPes7843_2320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL20485.1 .
AE009952 Genomic DNA. Translation: AAM86019.1 . Different initiation.
AE017042 Genomic DNA. Translation: AAS61783.1 .
PIRi AB0225.
RefSeqi NP_992906.1. NC_005810.1.
YP_002346839.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8ZF73.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO1845.

Proteomic databases

PRIDEi Q8ZF73.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM86019 ; AAM86019 ; y2462 .
AAS61783 ; AAS61783 ; YP_1548 .
GeneIDi 1174680.
2764100.
KEGGi ype:YPO1845.
ypm:YP_1548.
PATRICi 18593206. VBIYerPes7843_2320.

Phylogenomic databases

eggNOGi COG2515.
HOGENOMi HOG000022459.
KOi K05396.
OMAi IMAQSFE.
OrthoDBi EOG6FBX0P.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-1819-MONOMER.

Family and domain databases

HAMAPi MF_01045. D_Cys_desulfhydr.
InterProi IPR027278. ACCD_DCysDesulf.
IPR005966. D-Cys_desShydrase.
IPR023702. D_Cys_desulphydr_bac.
IPR001926. TrpB-like_PLP-dep.
[Graphical view ]
Pfami PF00291. PALP. 1 hit.
[Graphical view ]
PIRSFi PIRSF006278. ACCD_DCysDesulf. 1 hit.
SUPFAMi SSF53686. SSF53686. 1 hit.
TIGRFAMsi TIGR01275. ACC_deam_rel. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiDCYD_YERPE
AccessioniPrimary (citable) accession number: Q8ZF73
Secondary accession number(s): Q0WFU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3