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Protein

NAD(P)H dehydrogenase (quinone)

Gene

YPO1857

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12NAD(P)UniRule annotation1
Binding sitei99SubstrateUniRule annotation1
Binding sitei134FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15FMNUniRule annotation6
Nucleotide bindingi79 – 81FMNUniRule annotation3
Nucleotide bindingi114 – 119FMNUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:YPO1857, y2449, YP_1536
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002007591 – 199NAD(P)H dehydrogenase (quinone)Add BLAST199

Proteomic databases

PaxDbiQ8ZF61

Interactioni

Protein-protein interaction databases

STRINGi187410.y2449

Structurei

3D structure databases

ProteinModelPortaliQ8ZF61
SMRiQ8ZF61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 190Flavodoxin-likeUniRule annotationAdd BLAST187

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CS1 Bacteria
COG0655 LUCA
HOGENOMiHOG000030539
KOiK03809
OMAiVGVPYAC

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZF61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKILVLYYS MYGHIETLAG AIAEGARKVS GVDVTIKRVP ETMPAEAFAK
60 70 80 90 100
AGGKTNQQAP VATPHELADY DGIIFGTPTR FGNMSGQMRT FLDQTGGLWA
110 120 130 140 150
SGALYGKVAS VFASTGTGGG QEHTITSTWT TLAHHGFIIV PIGYGAKELF
160 170 180 190
DVSQTRGGTP YGATTIAGGD GSRQPSAEEL AIARFQGEHV AKITAKLKG
Length:199
Mass (Da):20,808
Last modified:March 1, 2002 - v1
Checksum:i1CA884408B326512
GO

Sequence cautioni

The sequence AAM86006 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAS61771 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL20497.1
AE009952 Genomic DNA Translation: AAM86006.1 Different initiation.
AE017042 Genomic DNA Translation: AAS61771.1 Different initiation.
PIRiAF0226
RefSeqiWP_002211168.1, NZ_PDBR01000007.1
YP_002346851.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM86006; AAM86006; y2449
AAS61771; AAS61771; YP_1536
GeneIDi1174692
KEGGiype:YPO1857
ypj:CH55_818
ypk:y2449
ypl:CH46_3266
ypm:YP_1536
ypv:BZ15_1693
ypw:CH59_3309
PATRICifig|214092.21.peg.2222

Similar proteinsi

Entry informationi

Entry nameiNQOR_YERPE
AccessioniPrimary (citable) accession number: Q8ZF61
Secondary accession number(s): Q0WFT7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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