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Q8ZEV7

- SYR_YERPE

UniProt

Q8ZEV7 - SYR_YERPE

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPES214092:GKDD-2021-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:YPO2046, y2266, YP_1889
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 576576Arginine--tRNA ligasePRO_0000151641Add
BLAST

Proteomic databases

PRIDEiQ8ZEV7.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

IntActiQ8ZEV7. 4 interactions.
STRINGi214092.YPO2046.

Structurei

3D structure databases

ProteinModelPortaliQ8ZEV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi124 – 1329"HIGH" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247212.
KOiK01887.
OMAiDIMAESA.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZEV7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNIQALLSDK VSQALIAAGA PADCEAQVRQ SAKAQFGDYQ ANGVMAVAKK
60 70 80 90 100
LGMQPRQLAE RVVELLDLTG IASKIEIAGP GFINIFLDRQ WVAEKVEYAL
110 120 130 140 150
TAPKLGVAPV EPQTIVVDYS APNVAKQMHV GHLRSTIIGD AAVRTLAFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKMQNEN ASDMGLSDLE LFYQQAKKTY
210 220 230 240 250
DEDEEFALRA RAYVVKLQSG DEYCRQMWRK LVDITMAQNQ VAYDRLNVTL
260 270 280 290 300
TKDDVMGESL YNAMLPEIVA DLKAKGLAVE SEGATVVYLD EYKNKDGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLGA DRILYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPE SVPLEHHMFG MMLGKDGKPF KTRSGGTVKL SDLLDEAVER
410 420 430 440 450
AGKLIAEKNP DMPADELKQV INAVGIGAVK YADLSKSRTT DYIFDWDNML
460 470 480 490 500
ALDGNTAPYM QYAYTRVVSV FRRAGVDETS LTLPLVVTED REATLATRLL
510 520 530 540 550
QFEEIITTVA REGTPHVMCS YLYDLAGLFS SFYEHCQILN AESEEIRQSR
560 570
LKLAMLTAKT LKQGLDTLGI QTVERM
Length:576
Mass (Da):64,142
Last modified:March 1, 2002 - v1
Checksum:i0C38BDF10B0206E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL20681.1.
AE009952 Genomic DNA. Translation: AAM85826.1.
AE017042 Genomic DNA. Translation: AAS62107.1.
PIRiAF0249.
RefSeqiNP_669575.1. NC_004088.1.
NP_993230.1. NC_005810.1.
YP_002347028.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM85826; AAM85826; y2266.
AAS62107; AAS62107; YP_1889.
GeneIDi1147213.
1174884.
2764785.
KEGGiype:YPO2046.
ypk:y2266.
ypm:YP_1889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL20681.1 .
AE009952 Genomic DNA. Translation: AAM85826.1 .
AE017042 Genomic DNA. Translation: AAS62107.1 .
PIRi AF0249.
RefSeqi NP_669575.1. NC_004088.1.
NP_993230.1. NC_005810.1.
YP_002347028.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8ZEV7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8ZEV7. 4 interactions.
STRINGi 214092.YPO2046.

Proteomic databases

PRIDEi Q8ZEV7.

Protocols and materials databases

DNASUi 1147213.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM85826 ; AAM85826 ; y2266 .
AAS62107 ; AAS62107 ; YP_1889 .
GeneIDi 1147213.
1174884.
2764785.
KEGGi ype:YPO2046.
ypk:y2266.
ypm:YP_1889.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247212.
KOi K01887.
OMAi DIMAESA.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-2021-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiSYR_YERPE
AccessioniPrimary (citable) accession number: Q8ZEV7
Secondary accession number(s): Q0WFB0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3