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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi46ZincPROSITE-ProRule annotation1
Metal bindingi49ZincPROSITE-ProRule annotation1
Metal bindingi95ZincPROSITE-ProRule annotation1
Metal bindingi98ZincPROSITE-ProRule annotation1
Active sitei118NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Ordered Locus Names:YPO2158, y2164, YP_1958
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001403181 – 137Peptide methionine sulfoxide reductase MsrBAdd BLAST137

Proteomic databases

PaxDbiQ8ZEK7

Interactioni

Protein-protein interaction databases

STRINGi187410.y2164

Structurei

3D structure databases

ProteinModelPortaliQ8ZEK7
SMRiQ8ZEK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 129MsrBPROSITE-ProRule annotationAdd BLAST123

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X Bacteria
COG0229 LUCA
HOGENOMiHOG000243425
KOiK07305
OMAiYKASHKF

Family and domain databases

HAMAPiMF_01400 MsrB, 1 hit
InterProiView protein in InterPro
IPR028427 Met_Sox_Rdtase
IPR002579 Met_Sox_Rdtase_MsrB
IPR011057 Mss4-like_sf
PANTHERiPTHR10173 PTHR10173, 1 hit
PfamiView protein in Pfam
PF01641 SelR, 1 hit
SUPFAMiSSF51316 SSF51316, 1 hit
TIGRFAMsiTIGR00357 TIGR00357, 1 hit
PROSITEiView protein in PROSITE
PS51790 MSRB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZEK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKELNPTEN IEKLSDIQRY VTQERGTEAP FTGKLLHNKR DGVYQCLCCH
60 70 80 90 100
QPLFISESKF DSGCGWPSFY QPIDADSIRY IDDYSHNMHR IEIRCGNCDA
110 120 130
HLGHVFPDGP QPTGERYCIN SASLNFVDDQ NGEQTAG
Length:137
Mass (Da):15,515
Last modified:March 1, 2002 - v1
Checksum:i524C5D055610C37C
GO

Sequence cautioni

The sequence AAM85726 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAS62175 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL20789.1
AE009952 Genomic DNA Translation: AAM85726.1 Different initiation.
AE017042 Genomic DNA Translation: AAS62175.1 Different initiation.
PIRiAB0263
RefSeqiWP_002211677.1, NZ_PDBR01000052.1
YP_002347133.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM85726; AAM85726; y2164
AAS62175; AAS62175; YP_1958
GeneIDi1174992
KEGGiype:YPO2158
ypk:y2164
ypm:YP_1958
PATRICifig|214092.21.peg.2544

Entry informationi

Entry nameiMSRB_YERPE
AccessioniPrimary (citable) accession number: Q8ZEK7
Secondary accession number(s): Q0WF05
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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