Reviewed, UniProtKB/Swiss-Prot Q8ZEK1 (SELD_YERPE)

Names and origin

Protein names

Recommended name:
    Selenide, water dikinase
    EC=2.7.9.3
Alternative name(s):
    Selenophosphate synthetase
    Selenium donor protein

Gene names

Name:	selD
Ordered Locus Names:	YPO2164, y2157, YP_1964

Organism

Yersinia pestis [Complete proteome] [HAMAP]

Taxonomic identifier

632 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity.
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the selenophosphate synthetase 1 family. Class I subfamily.

Ontologies

Keywords
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP selenium binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Selenide, water dikinase HAMAP MF_00625		PRO_0000127643
Regions
	Nucleotide binding	230 – 236	7	ATP Potential
Sites
	Active site	17	1	Potential
	Site	20	1	Important for catalytic activity By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8ZEK1-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 90D1B3A257B0582B	FASTA	348	36,623
	10 20 30 40 50 60 MASPAIRLTQ YSHGAGCGCK ISPKVLDKIL HTEQQKFFDP RLLVGNETRD DAAVYDIGNG 70 80 90 100 110 120 VGIISTTDFF MPIVDDPFDF GRIAATNAIS DVYAMGGKPI MAIAILGWPI DKLAPEIAQQ 130 140 150 160 170 180 VIEGGRYVCQ QAGISLAGGH SIDAPEPILG LAVTGIVSTE QVKKNSAAKP GCKLFLTKPL 190 200 210 220 230 240 GIGILTTAEK KSKLRPEHRG LATETMCQLN KPGADFAHIP GVTAMTDVTG FGLLGHLSEI 250 260 270 280 290 300 CQGSGVQAIL HYSAIPRLPA VEDYIAEGCV PGGTGRNFDS YGHLIGNMSD LQKQLLCDPQ 310 320 330 340 TSGGLLLAVL PDAEADVQAI AAQHGMTLSP IGELTSADSR RALIEIVV

References

[1]	"Genome sequence of Yersinia pestis, the causative agent of plague." Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:523-527(2001) [PubMed: 11586360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CO-92 / Biovar Orientalis.
[2]	"Genome sequence of Yersinia pestis KIM." Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. , Matson J.S., Blattner F.R., Perry R.D. J. Bacteriol. 184:4601-4611(2002) [PubMed: 12142430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIM5 / Biovar Mediaevalis.
[3]	"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans." Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R. DNA Res. 11:179-197(2004) [PubMed: 15368893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 91001 / Biovar Mediaevalis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL590842 Genomic DNA. Translation: CAL20795.1. AE009952 Genomic DNA. Translation: AAM85719.1. AE017042 Genomic DNA. Translation: AAS62181.1.
PIR	AH0263.
RefSeq	NP_669468.1. NP_993304.1. YP_002347139.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1147104. 1174998. 2766369.
GenomeReviews	Gene locus y2157 in contig AE009952_GR. Gene locus YP_1964 in contig AE017042_GR. Gene locus YPO2164 in contig AL590842_GR.
KEGG	ype:YPO2164. ypk:y2157. ypm:YP_1964.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8ZEK1.
OMA	GGRFACQ.
Enzyme and pathway databases
BioCyc	YPES187410:Y2157-MON. YPES214092:YPO2164-MON. YPES229193:YP1964-MON.
BRENDA	2.7.9.3. 142588.
Family and domain databases
HAMAP	MF_00625. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004536. SelD. [Graphical view]
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
TIGRFAMs	TIGR00476. selD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_YERPE

Accession

Primary (citable) accession number: Q8ZEK1
Secondary accession number(s): Q0WEZ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)