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Q8ZD92

- CPDP_YERPE

UniProt

Q8ZD92 - CPDP_YERPE

Protein

Probable 3',5'-cyclic-nucleotide phosphodiesterase

Gene

cpdP

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

    GO - Molecular functioni

    1. 3',5'-cyclic-AMP phosphodiesterase activity Source: InterPro

    GO - Biological processi

    1. cAMP catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    cAMP

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-2663-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable 3',5'-cyclic-nucleotide phosphodiesterase (EC:3.1.4.17)
    Short name:
    3':5'-CNP
    Short name:
    PDEase
    Gene namesi
    Name:cpdP
    Ordered Locus Names:YPO2696, y1271, YP_2500
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Periplasm By similarity

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3636Sequence AnalysisAdd
    BLAST
    Chaini37 – 343307Probable 3',5'-cyclic-nucleotide phosphodiesterasePRO_0000023355Add
    BLAST

    Proteomic databases

    PRIDEiQ8ZD92.

    Interactioni

    Protein-protein interaction databases

    STRINGi214092.YPO2696.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZD92.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG5212.
    HOGENOMiHOG000219486.
    KOiK01120.
    OMAiTIMAREE.
    OrthoDBiEOG67T5G8.

    Family and domain databases

    Gene3Di3.60.15.10. 1 hit.
    InterProiIPR001279. Beta-lactamas-like.
    IPR024225. cAMP-PdiesteraseII_CS.
    IPR000396. Pdiesterase2.
    [Graphical view]
    PfamiPF02112. PDEase_II. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000962. Cyc_nuc_PDEase. 1 hit.
    PRINTSiPR00388. PDIESTERASE2.
    SUPFAMiSSF56281. SSF56281. 1 hit.
    PROSITEiPS00607. PDEASE_II. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8ZD92-1 [UniParc]FASTAAdd to Basket

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    MKYLSIKSAS DKIKSGLLKT GVILSFSLFS SLSTAAFEVV ALGVDGGVSD    50
    GNLTSYLIRN DSQPLYLGLD AGSVLPGIAR ALEKGHFAAI TDAMAAPLTR 100
    QGYIFRQSIN SYFISHAHLD HVSGLIIGSP DDSKKTIYAS ADTIDVLRNY 150
    YFNWRVWPNF TDSGSGARLG TYRMQVVRPA QSLSLGLTRL TGEMYPLSHD 200
    KSPSSMLLIS SNNEFFAYFG DTGPDDVEKS KNLDTVWRKL AEKVTQQQLK 250
    GMIIEVSYPN DVADNKLFGH MTPTWLLKEL KKLEQYSGEG QPLKGLPVVI 300
    SHIKPSFQQG QDVRKLILSE LQQGNDMGIE FILMEQGDSQ KFQ 343
    Length:343
    Mass (Da):37,874
    Last modified:March 1, 2002 - v1
    Checksum:iB694C1AEA9C01F57
    GO

    Sequence cautioni

    The sequence AAM84845.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAS62699.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21315.1.
    AE009952 Genomic DNA. Translation: AAM84845.1. Different initiation.
    AE017042 Genomic DNA. Translation: AAS62699.1. Different initiation.
    PIRiAH0328.
    RefSeqiNP_668594.1. NC_004088.1.
    NP_993822.1. NC_005810.1.
    YP_002347644.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM84845; AAM84845; y1271.
    AAS62699; AAS62699; YP_2500.
    GeneIDi1146218.
    1175526.
    2764764.
    KEGGiype:YPO2696.
    ypk:y1271.
    ypm:YP_2500.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21315.1 .
    AE009952 Genomic DNA. Translation: AAM84845.1 . Different initiation.
    AE017042 Genomic DNA. Translation: AAS62699.1 . Different initiation.
    PIRi AH0328.
    RefSeqi NP_668594.1. NC_004088.1.
    NP_993822.1. NC_005810.1.
    YP_002347644.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZD92.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214092.YPO2696.

    Proteomic databases

    PRIDEi Q8ZD92.

    Protocols and materials databases

    DNASUi 1146218.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM84845 ; AAM84845 ; y1271 .
    AAS62699 ; AAS62699 ; YP_2500 .
    GeneIDi 1146218.
    1175526.
    2764764.
    KEGGi ype:YPO2696.
    ypk:y1271.
    ypm:YP_2500.

    Phylogenomic databases

    eggNOGi COG5212.
    HOGENOMi HOG000219486.
    KOi K01120.
    OMAi TIMAREE.
    OrthoDBi EOG67T5G8.

    Enzyme and pathway databases

    BioCyci YPES214092:GKDD-2663-MONOMER.

    Family and domain databases

    Gene3Di 3.60.15.10. 1 hit.
    InterProi IPR001279. Beta-lactamas-like.
    IPR024225. cAMP-PdiesteraseII_CS.
    IPR000396. Pdiesterase2.
    [Graphical view ]
    Pfami PF02112. PDEase_II. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000962. Cyc_nuc_PDEase. 1 hit.
    PRINTSi PR00388. PDIESTERASE2.
    SUPFAMi SSF56281. SSF56281. 1 hit.
    PROSITEi PS00607. PDEASE_II. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiCPDP_YERPE
    AccessioniPrimary (citable) accession number: Q8ZD92
    Secondary accession number(s): Q0WDJ4, Q8CLI4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 7, 2003
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3