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Q8ZD92 (CPDP_YERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable 3',5'-cyclic-nucleotide phosphodiesterase

Short name=3':5'-CNP
Short name=PDEase
EC=3.1.4.17
Gene names
Name:cpdP
Ordered Locus Names:YPO2696, y1271, YP_2500
OrganismYersinia pestis [Reference proteome] [HAMAP]
Taxonomic identifier632 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the cAMP phosphodiesterase class-II family.

Sequence caution

The sequence AAM84845.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAS62699.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   LigandcAMP
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcAMP catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function3',5'-cyclic-AMP phosphodiesterase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3636 Potential
Chain37 – 343307Probable 3',5'-cyclic-nucleotide phosphodiesterase
PRO_0000023355

Sequences

Sequence LengthMass (Da)Tools
Q8ZD92 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: B694C1AEA9C01F57

FASTA34337,874
        10         20         30         40         50         60 
MKYLSIKSAS DKIKSGLLKT GVILSFSLFS SLSTAAFEVV ALGVDGGVSD GNLTSYLIRN 

        70         80         90        100        110        120 
DSQPLYLGLD AGSVLPGIAR ALEKGHFAAI TDAMAAPLTR QGYIFRQSIN SYFISHAHLD 

       130        140        150        160        170        180 
HVSGLIIGSP DDSKKTIYAS ADTIDVLRNY YFNWRVWPNF TDSGSGARLG TYRMQVVRPA 

       190        200        210        220        230        240 
QSLSLGLTRL TGEMYPLSHD KSPSSMLLIS SNNEFFAYFG DTGPDDVEKS KNLDTVWRKL 

       250        260        270        280        290        300 
AEKVTQQQLK GMIIEVSYPN DVADNKLFGH MTPTWLLKEL KKLEQYSGEG QPLKGLPVVI 

       310        320        330        340 
SHIKPSFQQG QDVRKLILSE LQQGNDMGIE FILMEQGDSQ KFQ 

« Hide

References

[1]"Genome sequence of Yersinia pestis, the causative agent of plague."
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. expand/collapse author list , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CO-92 / Biovar Orientalis.
[2]"Genome sequence of Yersinia pestis KIM."
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. expand/collapse author list , Matson J.S., Blattner F.R., Perry R.D.
J. Bacteriol. 184:4601-4611(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KIM10+ / Biovar Mediaevalis.
[3]"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. expand/collapse author list , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 91001 / Biovar Mediaevalis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL590842 Genomic DNA. Translation: CAL21315.1.
AE009952 Genomic DNA. Translation: AAM84845.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS62699.1. Different initiation.
PIRAH0328.
RefSeqNP_668594.1. NC_004088.1.
NP_993822.1. NC_005810.1.
YP_002347644.1. NC_003143.1.

3D structure databases

ProteinModelPortalQ8ZD92.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING214092.YPO2696.

Proteomic databases

PRIDEQ8ZD92.

Protocols and materials databases

DNASU1146218.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM84845; AAM84845; y1271.
AAS62699; AAS62699; YP_2500.
GeneID1146218.
1175526.
2764764.
KEGGype:YPO2696.
ypk:y1271.
ypm:YP_2500.

Phylogenomic databases

eggNOGCOG5212.
HOGENOMHOG000219486.
KOK01120.
OMATIMAREE.
OrthoDBEOG67T5G8.
ProtClustDBCLSK889264.

Enzyme and pathway databases

BioCycYPES214092:GKDD-2663-MONOMER.

Family and domain databases

Gene3D3.60.15.10. 1 hit.
InterProIPR001279. Beta-lactamas-like.
IPR024225. cAMP-PdiesteraseII_CS.
IPR000396. Pdiesterase2.
[Graphical view]
PfamPF02112. PDEase_II. 1 hit.
[Graphical view]
PIRSFPIRSF000962. Cyc_nuc_PDEase. 1 hit.
PRINTSPR00388. PDIESTERASE2.
SUPFAMSSF56281. SSF56281. 1 hit.
PROSITEPS00607. PDEASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCPDP_YERPE
AccessionPrimary (citable) accession number: Q8ZD92
Secondary accession number(s): Q0WDJ4, Q8CLI4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 7, 2003
Last sequence update: March 1, 2002
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families