Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8ZD80

- NADB_YERPE

UniProt

Q8ZD80 - NADB_YERPE

Protein

L-aspartate oxidase

Gene

nadB

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (30 Aug 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the oxidation of L-aspartate to iminoaspartate.

    Catalytic activityi

    L-aspartate + O2 = iminosuccinate + H2O2.

    Cofactori

    FAD.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei244 – 2441By similarity
    Active sitei263 – 2631By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi12 – 2615FADSequence AnalysisAdd
    BLAST

    GO - Molecular functioni

    1. L-aspartate:fumarate oxidoreductase activity Source: UniProtKB-EC
    2. L-aspartate oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Keywords - Ligandi

    FAD, Flavoprotein

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-2677-MONOMER.
    UniPathwayiUPA00253; UER00326.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L-aspartate oxidase (EC:1.4.3.16)
    Short name:
    LASPO
    Alternative name(s):
    Quinolinate synthase B
    Gene namesi
    Name:nadB
    Ordered Locus Names:YPO2710, y1289, YP_2514
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 533533L-aspartate oxidasePRO_0000184406Add
    BLAST

    Proteomic databases

    PRIDEiQ8ZD80.

    Interactioni

    Protein-protein interaction databases

    STRINGi214092.YPO2710.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZD80.
    SMRiQ8ZD80. Positions 6-533.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0029.
    HOGENOMiHOG000160476.
    KOiK00278.
    OMAiEINEYYW.
    OrthoDBiEOG696BWH.

    Family and domain databases

    Gene3Di1.20.58.100. 1 hit.
    3.90.700.10. 1 hit.
    InterProiIPR003953. FAD_bind_dom.
    IPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
    IPR005288. NadB.
    IPR027477. Succ_DH/fumarate_Rdtase_cat.
    [Graphical view]
    PfamiPF00890. FAD_binding_2. 1 hit.
    PF02910. Succ_DH_flav_C. 1 hit.
    [Graphical view]
    PRINTSiPR00368. FADPNR.
    SUPFAMiSSF46977. SSF46977. 1 hit.
    SSF56425. SSF56425. 1 hit.
    TIGRFAMsiTIGR00551. nadB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8ZD80-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQSSSEHISD VLIIGSGAAG LSLALRLAPH CKVTVLSKGP LNEGATFYAQ    50
    GGIAAVFDET DSISSHVDDT LIAGAGLCDK EAVEFIASNA RSCVQWLIDQ 100
    GVLFDTETSA NGEERYHLTR EGGHSHRRIL HTADATGKEV ETTLVGKASN 150
    HPNISVKERC NAVDLITSNK IGLAGTKRVV GAYVWNRELE KVETFRAKAV 200
    VLATGGAAKV YQYTTNPDIS SGDGIAMAWR AGCRVANLEF NQFHPTCLFH 250
    PQARNFLLTE ALRGEGAYLK RPDGSRFMLD FDPRGELAPR DIVARAIDHE 300
    MKRLGADCMY LDISHKPTDF VMQHFPMIYE KLLSLGIDLT KEAIPIVPAA 350
    HYTCGGVMVD QHGRTDLDGL YAIGEVSYTG LHGANRMASN SLLECLVYGW 400
    SAAEDILTRL PTAKLAKHLP DWDESRVDNS DERVVIQHNW HELRLFMWDY 450
    VGIVRTTKRL ERALRRINTL QQEIDEYYAN FRISNNLLEL RNLVQVAELI 500
    VRCAMERKES RGLHYTLDYP DQIENPQPTI LHP 533
    Length:533
    Mass (Da):59,294
    Last modified:August 30, 2002 - v2
    Checksum:i909E8BFEB15BD2BD
    GO

    Sequence cautioni

    The sequence AAM84863.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAS62712.1 differs from that shown. Reason: Erroneous initiation.
    The sequence CAL21329.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21329.1. Different initiation.
    AE009952 Genomic DNA. Translation: AAM84863.1. Different initiation.
    AE017042 Genomic DNA. Translation: AAS62712.1. Different initiation.
    PIRiAF0330.
    RefSeqiNP_668612.1. NC_004088.1.
    NP_993835.1. NC_005810.1.
    YP_002347657.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM84863; AAM84863; y1289.
    AAS62712; AAS62712; YP_2514.
    GeneIDi1146236.
    1175540.
    2764388.
    KEGGiype:YPO2710.
    ypk:y1289.
    ypm:YP_2514.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21329.1 . Different initiation.
    AE009952 Genomic DNA. Translation: AAM84863.1 . Different initiation.
    AE017042 Genomic DNA. Translation: AAS62712.1 . Different initiation.
    PIRi AF0330.
    RefSeqi NP_668612.1. NC_004088.1.
    NP_993835.1. NC_005810.1.
    YP_002347657.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZD80.
    SMRi Q8ZD80. Positions 6-533.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214092.YPO2710.

    Proteomic databases

    PRIDEi Q8ZD80.

    Protocols and materials databases

    DNASUi 1146236.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM84863 ; AAM84863 ; y1289 .
    AAS62712 ; AAS62712 ; YP_2514 .
    GeneIDi 1146236.
    1175540.
    2764388.
    KEGGi ype:YPO2710.
    ypk:y1289.
    ypm:YP_2514.

    Phylogenomic databases

    eggNOGi COG0029.
    HOGENOMi HOG000160476.
    KOi K00278.
    OMAi EINEYYW.
    OrthoDBi EOG696BWH.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00326 .
    BioCyci YPES214092:GKDD-2677-MONOMER.

    Family and domain databases

    Gene3Di 1.20.58.100. 1 hit.
    3.90.700.10. 1 hit.
    InterProi IPR003953. FAD_bind_dom.
    IPR013027. FAD_pyr_nucl-diS_OxRdtase.
    IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
    IPR005288. NadB.
    IPR027477. Succ_DH/fumarate_Rdtase_cat.
    [Graphical view ]
    Pfami PF00890. FAD_binding_2. 1 hit.
    PF02910. Succ_DH_flav_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00368. FADPNR.
    SUPFAMi SSF46977. SSF46977. 1 hit.
    SSF56425. SSF56425. 1 hit.
    TIGRFAMsi TIGR00551. nadB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiNADB_YERPE
    AccessioniPrimary (citable) accession number: Q8ZD80
    Secondary accession number(s): Q0WDI1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2002
    Last sequence update: August 30, 2002
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3