Reviewed,
UniProtKB/Swiss-Prot Q8ZCA7 (COPA_YERPE)
Last modified
November 25, 2008.
Version 67.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Copper-exporting P-type ATPase A EC=3.6.3.n1 | ||||
| Gene names |
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| Organism | Yersinia pestis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 632 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia |
Protein attributes
| Sequence length | 961 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Involved in copper export By similarity. |
| Catalytic activity | ATP + H(2)O + Cu(1+)(In) = ADP + phosphate + Cu(1+)(Out). |
| Subcellular location | Cell membrane; Multi-pass membrane proteinProbable. |
| Sequence similarities | Belongs to the cation transport ATPase (P-type) family. Type IB subfamily. Contains 3 HMA domains. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 961 | 961 | Copper-exporting P-type ATPase A | PRO_0000046325 | |||||
Regions | |||||||||
| Transmembrane | 316 – 336 | 21 | Potential | ||||||
| Transmembrane | 345 – 365 | 21 | Potential | ||||||
| Transmembrane | 381 – 401 | 21 | Potential | ||||||
| Transmembrane | 565 – 585 | 21 | Potential | ||||||
| Transmembrane | 592 – 612 | 21 | Potential | ||||||
| Transmembrane | 860 – 880 | 21 | Potential | ||||||
| Transmembrane | 906 – 926 | 21 | Potential | ||||||
| Transmembrane | 928 – 948 | 21 | Potential | ||||||
| Domain | 4 – 65 | 62 | HMA 1 | ||||||
| Domain | 70 – 131 | 62 | HMA 2 | ||||||
| Domain | 227 – 290 | 64 | HMA 3 | ||||||
Sites | |||||||||
| Active site | 650 | 1 | 4-aspartylphosphate intermediate Probable | ||||||
| Metal binding | 14 | 1 | Copper Potential | ||||||
| Metal binding | 17 | 1 | Copper Potential | ||||||
| Metal binding | 80 | 1 | Copper Potential | ||||||
| Metal binding | 83 | 1 | Copper Potential | ||||||
| Metal binding | 237 | 1 | Copper Potential | ||||||
| Metal binding | 240 | 1 | Copper Potential | ||||||
| Metal binding | 847 | 1 | Magnesium By similarity | ||||||
| Metal binding | 851 | 1 | Magnesium By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 376 | 1 | R → S Ref.2 Ref.3 | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| AL590842 Genomic DNA. Translation: CAL21688.1. AE009952 Genomic DNA. Translation: AAM84670.1. AE017042 Genomic DNA. Translation: AAS61097.1. | |
| PIR | AE0375. |
| RefSeq | NP_668419.1. NP_992220.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1AFJ based on UniProtKB P04129. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1146039. 2764600. |
| GenomeReviews | Gene locus y1093 in contig AE009952_GR. Gene locus YP_0838 in contig AE017042_GR. Gene locus YPO3086 in contig AL590842_GR. |
| KEGG | ype:YPO3086. ypk:y1093. ypm:YP_0838. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8ZCA7. |
Enzyme and pathway databases | |
| BioCyc | YPES187410:Y1093-MON. YPES214092:YPO3086-MON. YPES229193:YP0838-MON. |
Family and domain databases | |
| InterPro | IPR006416. ATPase-IB_hvy. IPR001757. ATPase_P. IPR006403. ATPase_P_cat/Cu. IPR005834. Dehalogen-like_hydro. IPR008250. E1-E2_ATPase_reg. IPR000695. H_ATPase. IPR006121. HeavyMe_transpt. [Graphical view] |
| PANTHER | PTHR11939. ATPase_P. 1 hit. |
| Pfam | PF00122. E1-E2_ATPase. 1 hit. PF00403. HMA. 3 hits. PF00702. Hydrolase. 1 hit. [Graphical view] |
| PRINTS | PR00119. CATATPASE. PR00120. HATPASE. |
| TIGRFAMs | TIGR01511. ATPase-IB1_Cu. 1 hit. TIGR01525. ATPase-IB_hvy. 1 hit. TIGR01494. ATPase_P-type. 2 hits. |
| PROSITE | PS00154. ATPASE_E1_E2. 1 hit. PS01047. HMA_1. 3 hits. PS50846. HMA_2. 3 hits. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | COPA_YERPE | ||||||||
| Accession | Primary (citable) accession number: Q8ZCA7 Secondary accession number(s): Q0WCI2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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