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Q8ZC31

- ACPH_YERPE

UniProt

Q8ZC31 - ACPH_YERPE

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Protein
Acyl carrier protein phosphodiesterase
Gene
acpH, YPO3193, y0989, YP_0738
Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity.UniRule annotation

Catalytic activityi

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

GO - Molecular functioni

  1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3147-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier protein phosphodiesterase (EC:3.1.4.14)
Short name:
ACP phosphodiesterase
Gene namesi
Name:acpH
Ordered Locus Names:YPO3193, y0989, YP_0738
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Acyl carrier protein phosphodiesteraseUniRule annotation
PRO_0000226278Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi214092.YPO3193.

Family & Domainsi

Sequence similaritiesi

Belongs to the AcpH family.

Phylogenomic databases

eggNOGiCOG3124.
HOGENOMiHOG000275880.
KOiK08682.
OMAiWLHRQID.
OrthoDBiEOG6K6V7H.

Family and domain databases

HAMAPiMF_01950. AcpH.
InterProiIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamiPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFiPIRSF011489. DUF479. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZC31-1 [UniParc]FASTAAdd to Basket

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MNFLAHLHLA ALADSSLLGN LLADFVRGNP QGEYPPEIVA GIMMHRRVDV    50
MTDTLPLVKE ARTYFSADYR RVSPITLDVL WDHFLARHWD QLVPNCTLPD 100
FLQHAQSQIL PHLPHTPARF QSLNAYLWSE RWLERYAELP FIADVLQGMA 150
NRRPKLAALA GSFYAIEQHY QPLEDLFLTF YPTMMRQAQH KQI 193
Length:193
Mass (Da):22,351
Last modified:March 1, 2002 - v1
Checksum:i6921FA82A025990A
GO

Sequence cautioni

The sequence AAM84570.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAS61003.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL21788.1.
AE009952 Genomic DNA. Translation: AAM84570.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS61003.1. Different initiation.
PIRiAI0387.
RefSeqiNP_668319.1. NC_004088.1.
NP_992126.1. NC_005810.1.
YP_002348098.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM84570; AAM84570; y0989.
AAS61003; AAS61003; YP_0738.
GeneIDi1145936.
1176008.
2765747.
KEGGiype:YPO3193.
ypk:y0989.
ypm:YP_0738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL21788.1 .
AE009952 Genomic DNA. Translation: AAM84570.1 . Different initiation.
AE017042 Genomic DNA. Translation: AAS61003.1 . Different initiation.
PIRi AI0387.
RefSeqi NP_668319.1. NC_004088.1.
NP_992126.1. NC_005810.1.
YP_002348098.1. NC_003143.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO3193.

Protocols and materials databases

DNASUi 1145936.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM84570 ; AAM84570 ; y0989 .
AAS61003 ; AAS61003 ; YP_0738 .
GeneIDi 1145936.
1176008.
2765747.
KEGGi ype:YPO3193.
ypk:y0989.
ypm:YP_0738.

Phylogenomic databases

eggNOGi COG3124.
HOGENOMi HOG000275880.
KOi K08682.
OMAi WLHRQID.
OrthoDBi EOG6K6V7H.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-3147-MONOMER.

Family and domain databases

HAMAPi MF_01950. AcpH.
InterProi IPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view ]
Pfami PF04336. DUF479. 1 hit.
[Graphical view ]
PIRSFi PIRSF011489. DUF479. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiACPH_YERPE
AccessioniPrimary (citable) accession number: Q8ZC31
Secondary accession number(s): Q0WC90, Q74WU4, Q8D165
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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