Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8ZC31 (ACPH_YERPE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl carrier protein phosphodiesterase

Short name=ACP phosphodiesterase
EC=3.1.4.14
Gene names
Name:acpH
Ordered Locus Names:YPO3193, y0989, YP_0738
OrganismYersinia pestis [Reference proteome] [HAMAP]
Taxonomic identifier632 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950

Catalytic activity

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950

Sequence similarities

Belongs to the AcpH family.

Sequence caution

The sequence AAM84570.1 differs from that shown. Reason: Erroneous initiation.

The sequence AAS61003.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 193193Acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950
PRO_0000226278

Sequences

Sequence LengthMass (Da)Tools
Q8ZC31 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 6921FA82A025990A

FASTA19322,351
        10         20         30         40         50         60 
MNFLAHLHLA ALADSSLLGN LLADFVRGNP QGEYPPEIVA GIMMHRRVDV MTDTLPLVKE 

        70         80         90        100        110        120 
ARTYFSADYR RVSPITLDVL WDHFLARHWD QLVPNCTLPD FLQHAQSQIL PHLPHTPARF 

       130        140        150        160        170        180 
QSLNAYLWSE RWLERYAELP FIADVLQGMA NRRPKLAALA GSFYAIEQHY QPLEDLFLTF 

       190 
YPTMMRQAQH KQI 

« Hide

References

[1]"Genome sequence of Yersinia pestis, the causative agent of plague."
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. expand/collapse author list , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CO-92 / Biovar Orientalis.
[2]"Genome sequence of Yersinia pestis KIM."
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. expand/collapse author list , Matson J.S., Blattner F.R., Perry R.D.
J. Bacteriol. 184:4601-4611(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KIM10+ / Biovar Mediaevalis.
[3]"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. expand/collapse author list , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 91001 / Biovar Mediaevalis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL590842 Genomic DNA. Translation: CAL21788.1.
AE009952 Genomic DNA. Translation: AAM84570.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS61003.1. Different initiation.
PIRAI0387.
RefSeqNP_668319.1. NC_004088.1.
NP_992126.1. NC_005810.1.
YP_002348098.1. NC_003143.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING214092.YPO3193.

Protocols and materials databases

DNASU1145936.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM84570; AAM84570; y0989.
AAS61003; AAS61003; YP_0738.
GeneID1145936.
1176008.
2765747.
KEGGype:YPO3193.
ypk:y0989.
ypm:YP_0738.

Phylogenomic databases

eggNOGCOG3124.
HOGENOMHOG000275880.
KOK08682.
OMAWLHRQID.
OrthoDBEOG6K6V7H.
ProtClustDBCLSK889429.

Enzyme and pathway databases

BioCycYPES214092:GKDD-3147-MONOMER.

Family and domain databases

HAMAPMF_01950. AcpH.
InterProIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFPIRSF011489. DUF479. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPH_YERPE
AccessionPrimary (citable) accession number: Q8ZC31
Secondary accession number(s): Q0WC90, Q74WU4, Q8D165
Entry history
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 1, 2002
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families