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Q8ZC31

- ACPH_YERPE

UniProt

Q8ZC31 - ACPH_YERPE

Protein

Acyl carrier protein phosphodiesterase

Gene

acpH

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.UniRule annotation

    Catalytic activityi

    Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

    GO - Molecular functioni

    1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-3147-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl carrier protein phosphodiesteraseUniRule annotation (EC:3.1.4.14UniRule annotation)
    Short name:
    ACP phosphodiesteraseUniRule annotation
    Gene namesi
    Name:acpHUniRule annotation
    Ordered Locus Names:YPO3193, y0989, YP_0738
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 193193Acyl carrier protein phosphodiesterasePRO_0000226278Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi214092.YPO3193.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AcpH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3124.
    HOGENOMiHOG000275880.
    KOiK08682.
    OMAiWLHRQID.
    OrthoDBiEOG6K6V7H.

    Family and domain databases

    HAMAPiMF_01950. AcpH.
    InterProiIPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view]
    PfamiPF04336. DUF479. 1 hit.
    [Graphical view]
    PIRSFiPIRSF011489. DUF479. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8ZC31-1 [UniParc]FASTAAdd to Basket

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    MNFLAHLHLA ALADSSLLGN LLADFVRGNP QGEYPPEIVA GIMMHRRVDV    50
    MTDTLPLVKE ARTYFSADYR RVSPITLDVL WDHFLARHWD QLVPNCTLPD 100
    FLQHAQSQIL PHLPHTPARF QSLNAYLWSE RWLERYAELP FIADVLQGMA 150
    NRRPKLAALA GSFYAIEQHY QPLEDLFLTF YPTMMRQAQH KQI 193
    Length:193
    Mass (Da):22,351
    Last modified:March 1, 2002 - v1
    Checksum:i6921FA82A025990A
    GO

    Sequence cautioni

    The sequence AAM84570.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAS61003.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21788.1.
    AE009952 Genomic DNA. Translation: AAM84570.1. Different initiation.
    AE017042 Genomic DNA. Translation: AAS61003.1. Different initiation.
    PIRiAI0387.
    RefSeqiNP_668319.1. NC_004088.1.
    NP_992126.1. NC_005810.1.
    YP_002348098.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM84570; AAM84570; y0989.
    AAS61003; AAS61003; YP_0738.
    GeneIDi1145936.
    1176008.
    2765747.
    KEGGiype:YPO3193.
    ypk:y0989.
    ypm:YP_0738.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL21788.1 .
    AE009952 Genomic DNA. Translation: AAM84570.1 . Different initiation.
    AE017042 Genomic DNA. Translation: AAS61003.1 . Different initiation.
    PIRi AI0387.
    RefSeqi NP_668319.1. NC_004088.1.
    NP_992126.1. NC_005810.1.
    YP_002348098.1. NC_003143.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214092.YPO3193.

    Protocols and materials databases

    DNASUi 1145936.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM84570 ; AAM84570 ; y0989 .
    AAS61003 ; AAS61003 ; YP_0738 .
    GeneIDi 1145936.
    1176008.
    2765747.
    KEGGi ype:YPO3193.
    ypk:y0989.
    ypm:YP_0738.

    Phylogenomic databases

    eggNOGi COG3124.
    HOGENOMi HOG000275880.
    KOi K08682.
    OMAi WLHRQID.
    OrthoDBi EOG6K6V7H.

    Enzyme and pathway databases

    BioCyci YPES214092:GKDD-3147-MONOMER.

    Family and domain databases

    HAMAPi MF_01950. AcpH.
    InterProi IPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view ]
    Pfami PF04336. DUF479. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF011489. DUF479. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiACPH_YERPE
    AccessioniPrimary (citable) accession number: Q8ZC31
    Secondary accession number(s): Q0WC90, Q74WU4, Q8D165
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 7, 2006
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3