true2002-06-062024-03-27137LUXS_YERPEGenome sequence of Yersinia pestis, the causative agent of plague.Parkhill J.Wren B.W.Thomson N.R.Titball R.W.Holden M.T.G.Prentice M.B.Sebaihia M.James K.D.Churcher C.M.Mungall K.L.Baker S.Basham D.Bentley S.D.Brooks K.Cerdeno-Tarraga A.-M.Chillingworth T.Cronin A.Davies R.M.Davis P.Dougan G.Feltwell T.Hamlin N.Holroyd S.Jagels K.Karlyshev A.V.Leather S.Moule S.Oyston P.C.F.Quail M.A.Rutherford K.M.Simmonds M.Skelton J.Stevens K.Whitehead S.Barrell B.G.doi:10.1038/350970832001Nature413523-527NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CO-92 / Biovar OrientalisGenome sequence of Yersinia pestis KIM.Deng W.Burland V.Plunkett G. IIIBoutin A.Mayhew G.F.Liss P.Perna N.T.Rose D.J.Mau B.Zhou S.Schwartz D.C.Fetherston J.D.Lindler L.E.Brubaker R.R.Plano G.V.Straley S.C.McDonough K.A.Nilles M.L.Matson J.S.Blattner F.R.Perry R.D.doi:10.1128/jb.184.16.4601-4611.20022002J. Bacteriol.1844601-4611NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]KIM10+ / Biovar MediaevalisComplete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.Song Y.Tong Z.Wang J.Wang L.Guo Z.Han Y.Zhang J.Pei D.Zhou D.Qin H.Pang X.Han Y.'Zhai J.Li M.Cui B.Qi Z.Jin L.Dai R.Chen F.Li S.Ye C.Du Z.Lin W.Wang J.'Yu J.Yang H.Wang J.''Huang P.Yang R.doi:10.1093/dnares/11.3.1792004DNA Res.11179-197NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]91001 / Biovar Mediaevalis1BacteriaS-ribosylhomocysteinase (LuxS)LuxSLuxS_sfMetalloenz_LuxS/M16S-ribosylhomocysteinaseS-RIBOSYLHOMOCYSTEINE LYASES-RIBOSYLHOMOCYSTEINE LYASELuxSAI2LUXSPROTEINLuxS/MPP-like metallohydrolaseS-ribosylhomocysteine lyase4.4.1.21AI-2 synthesis proteinAutoinducer-2 production protein LuxSluxSYPO3300y0888YP_0386Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).Binds 1 Fe cation per subunit.Homodimer.Belongs to the LuxS family.Removed1S-ribosylhomocysteine lyase19265217154581282007-01-23319396a13cdff49cc1c2efd247d8f22a1b50f9MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHItruetrue