Reviewed, UniProtKB/Swiss-Prot Q8ZB04 (SSUD_YERPE)

Names and origin

Protein names

Recommended name:
    Alkanesulfonate monooxygenase
    EC=1.14.14.5
Alternative name(s):
    FMNH2-dependent aliphatic sulfonate monooxygenase

Gene names

Name:	ssuD
Ordered Locus Names:	YPO3625, y0244, YP_3922

Organism

Yersinia pestis [Complete proteome] [HAMAP]

Taxonomic identifier

632 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the desulfonation of aliphatic sulfonates By similarity.
Catalytic activity	An alkanesufonate (R-CH(2)-SO(3)H) + FMNH(2) + O(2) = an aldehyde (R-CHO) + FMN + sulfite + H(2)O.
Subunit structure	Homotetramer By similarity.
Miscellaneous	FMNH(2) which is absolutely required for this enzymatic reaction, is provided by ssuE By similarity.
Sequence similarities	Belongs to the ssuD family.

Ontologies

Keywords
Ligand	FMN
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alkanesulfonate monooxygenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 382	382	Alkanesulfonate monooxygenase		PRO_0000216722

Sequences

	Sequence		Length	Mass (Da)
	Q8ZB04-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 1C6798E66F573BB0	FASTA	382	41,547
	10 20 30 40 50 60 MSINVFWFLP THGDGHYLGS SEGARAVDYS YLQQIAQAAD RLGFGGVLIP TGRSCEDSWL 70 80 90 100 110 120 VAASLIPVTQ RLKFLVALRP GIISPTLAAR QAATLDRLSN GRALFNLVTG GDPEELAAEG 130 140 150 160 170 180 LHLNHTERYE ASAEFTHVWR KVLEGETVDF AGKHIQVKGA KLLFPPVQHP RPPLYFGGSS 190 200 210 220 230 240 AAAQDLAAEQ VELYLTWGEP PEQVKEKIEE VRAKAAAKGR TVRFGIRLHV IVRETTEEAW 250 260 270 280 290 300 RAANRLIANL DDKTIADAQQ AFAGFDSVGQ QRMAALHGGK KDNLEISPNL WAGVGLVRGG 310 320 330 340 350 360 AGTALVGDGP TVAQRIQEYA DLGIDTFVFS GYPHLEEAYR VSELLFPHLD LATTELPTQR 370 380 PATQPQGEVV ANIYVPQKVS QS

References

[1]	"Genome sequence of Yersinia pestis, the causative agent of plague." Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:523-527(2001) [PubMed: 11586360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CO-92 / Biovar Orientalis.
[2]	"Genome sequence of Yersinia pestis KIM." Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. , Matson J.S., Blattner F.R., Perry R.D. J. Bacteriol. 184:4601-4611(2002) [PubMed: 12142430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIM5 / Biovar Mediaevalis.
[3]	"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans." Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R. DNA Res. 11:179-197(2004) [PubMed: 15368893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 91001 / Biovar Mediaevalis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL590842 Genomic DNA. Translation: CAL22213.1. AE009952 Genomic DNA. Translation: AAM83838.1. AE017042 Genomic DNA. Translation: AAS64067.1.
PIR	AB0441.
RefSeq	NP_667587.1. NP_995190.1.
3D structure databases
HSSP	HSSP built from PDB template 1M41 based on UniProtKB P80645.
SMR	Q8ZB04. Positions 1-361.
ModBase	Search...
Genome annotation databases
GeneID	1145191. 2767065.
GenomeReviews	Gene locus y0244 in contig AE009952_GR. Gene locus YP_3922 in contig AE017042_GR. Gene locus YPO3625 in contig AL590842_GR.
KEGG	ype:YPO3625. ypk:y0244. ypm:YP_3922.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8ZB04.
Enzyme and pathway databases
BioCyc	YPES187410:Y0244-MON. YPES214092:YPO3625-MON. YPES229193:YP3922-MON.
Family and domain databases
HAMAP	MF_01229. [Tree]
InterPro	IPR011251. Luciferase-like_bac. IPR016048. Luciferase_mOase. [Graphical view]
Gene3D	G3DSA:3.20.20.30. Luciferase_like. 1 hit.
Pfam	PF00296. Bac_luciferase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SSUD_YERPE

Accession

Primary (citable) accession number: Q8ZB04
Secondary accession number(s): Q0WB28

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2003
Last sequence update:	March 1, 2002
Last modified:	November 4, 2008
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)