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Q8ZAS2

- G6PI_YERPE

UniProt

Q8ZAS2 - G6PI_YERPE

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (27 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorUniRule annotation
    Active sitei386 – 3861UniRule annotation
    Active sitei514 – 5141UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-3674-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:YPO3718, y0024, YP_3080
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 548548Glucose-6-phosphate isomerasePRO_0000180775Add
    BLAST

    Proteomic databases

    PRIDEiQ8ZAS2.

    Interactioni

    Protein-protein interaction databases

    STRINGi214092.YPO3718.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZAS2.
    SMRiQ8ZAS2. Positions 7-548.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZAS2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNINPSQTA AWKALQQHFE QMKDVTISSL FAKDDQRFNR FSATFDDQML    50
    VDFSKNRITS ETLEKLQDLA KETDLAGAIK SMFSGEKINR TEDRAVLHIA 100
    LRNRSNTPIV VDGKDVMPEV NAVLAKMKQF CDRVISGDWK GYTGKAITDV 150
    VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA EALKPLNPET 200
    TLFLVASKTF TTQETMTNAH SARDWFLSAA GDPAHVAKHF AALSTNAKAV 250
    GEFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSVGFEHF EQLLSGAHAM 300
    DKHFAETPAE KNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFPAYFQ 350
    QGNMESNGKY VDRNGHPVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLIP 400
    CDFIAPAISH NPLSDHHAKL LSNFFAQTEA LAFGKSLEDV EAEFAAAGKT 450
    PEQVAHVAPF KVFEGNRPTN SILLREITPF SLGALIALYE HKIFTQGVIL 500
    NIYTFDQWGV ELGKQLANRI LPELADDQEV TSHDSSTNAL INRFKNWR 548
    Length:548
    Mass (Da):61,161
    Last modified:March 27, 2002 - v1
    Checksum:i3ED9D49B3A308A3B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti297 – 2971A → S in AAS63251. (PubMed:15368893)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL22305.1.
    AE009952 Genomic DNA. Translation: AAM83619.1.
    AE017042 Genomic DNA. Translation: AAS63251.1.
    PIRiAF0452.
    RefSeqiNP_667368.1. NC_004088.1.
    NP_994374.1. NC_005810.1.
    YP_002348599.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM83619; AAM83619; y0024.
    AAS63251; AAS63251; YP_3080.
    GeneIDi1144971.
    1176537.
    2763340.
    KEGGiype:YPO3718.
    ypk:y0024.
    ypm:YP_3080.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL22305.1 .
    AE009952 Genomic DNA. Translation: AAM83619.1 .
    AE017042 Genomic DNA. Translation: AAS63251.1 .
    PIRi AF0452.
    RefSeqi NP_667368.1. NC_004088.1.
    NP_994374.1. NC_005810.1.
    YP_002348599.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZAS2.
    SMRi Q8ZAS2. Positions 7-548.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214092.YPO3718.

    Proteomic databases

    PRIDEi Q8ZAS2.

    Protocols and materials databases

    DNASUi 1144971.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM83619 ; AAM83619 ; y0024 .
    AAS63251 ; AAS63251 ; YP_3080 .
    GeneIDi 1144971.
    1176537.
    2763340.
    KEGGi ype:YPO3718.
    ypk:y0024.
    ypm:YP_3080.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci YPES214092:GKDD-3674-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiG6PI_YERPE
    AccessioniPrimary (citable) accession number: Q8ZAS2
    Secondary accession number(s): Q0WAT9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 27, 2002
    Last sequence update: March 27, 2002
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3