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Protein

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Gene

glpB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.UniRule annotation

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FMNUniRule annotation

Pathway:iglycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3796-MONOMER.
UniPathwayiUPA00618; UER00673.

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit BUniRule annotation (EC:1.1.5.3UniRule annotation)
Short name:
Anaerobic G-3-P dehydrogenase subunit BUniRule annotation
Short name:
Anaerobic G3Pdhase BUniRule annotation
Gene namesi
Name:glpBUniRule annotation
Ordered Locus Names:YPO3825, y0405, YP_3223
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815 Componenti: Chromosome UP000001019 Componenti: Chromosome UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 424424Anaerobic glycerol-3-phosphate dehydrogenase subunit BPRO_0000204571Add
BLAST

Interactioni

Subunit structurei

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.UniRule annotation

Protein-protein interaction databases

STRINGi187410.y0405.

Structurei

3D structure databases

ProteinModelPortaliQ8ZAH6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3075.
HOGENOMiHOG000278489.
KOiK00112.
OMAiDVFEVPM.
OrthoDBiEOG6K6V62.

Family and domain databases

HAMAPiMF_00753. Glycerol3P_GlpB.
InterProiIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsiTIGR03378. glycerol3P_GlpB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZAH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFDVIIIGG GLAGLACGIR LAEQGKYCAI VSSGQNALHF SSGSLDLLAK
60 70 80 90 100
LPDGQAVSQP LSALSALAEL APEHPYSKMR NITQLDELVQ EAEALLRRCG
110 120 130 140 150
LDIVGSSAEN HLRLTPLGSC RPTWLSLADI PVAPLNGPLP WQRVAVIGIE
160 170 180 190 200
GFLDFQPQMV ASALQDQGID ATADYLHLPA LDRLRDNPSE FRAVNIARIL
210 220 230 240 250
DLPENRQPLA DELSRLSSTA EMILLPACIG LDKSAPLDAL RAVVGKPIQL
260 270 280 290 300
LPTLPPSLLG MRLHQALRHR FQQLGGLVMP GDAVLRAELV DNRITGLYSR
310 320 330 340 350
NHGDIPLRAA QMVLASGSFF SNGLVATFDK IYEPILDLDI LSLPHRADWS
360 370 380 390 400
HSNLFAPQPY LQFGVNTDNH LRPLRGGVAL ENLHAIGAVL GGYDPLQQGC
410 420
GAGVSLTSAV FVAEQIISEM AVTL
Length:424
Mass (Da):45,506
Last modified:March 1, 2002 - v1
Checksum:iCEC65C3081A809E7
GO

Sequence cautioni

The sequence AAM83994.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAS63391.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22412.1.
AE009952 Genomic DNA. Translation: AAM83994.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63391.1. Different initiation.
PIRiAI0465.
RefSeqiWP_002211492.1. NZ_KN150726.1.
YP_002348703.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM83994; AAM83994; y0405.
AAS63391; AAS63391; YP_3223.
GeneIDi1176660.
KEGGiype:YPO3825.
ypj:CH55_3190.
ypk:y0405.
ypl:CH46_1241.
ypm:YP_3223.
ypv:BZ15_3891.
ypw:CH59_1760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22412.1.
AE009952 Genomic DNA. Translation: AAM83994.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63391.1. Different initiation.
PIRiAI0465.
RefSeqiWP_002211492.1. NZ_KN150726.1.
YP_002348703.1. NC_003143.1.

3D structure databases

ProteinModelPortaliQ8ZAH6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187410.y0405.

Protocols and materials databases

DNASUi1145352.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM83994; AAM83994; y0405.
AAS63391; AAS63391; YP_3223.
GeneIDi1176660.
KEGGiype:YPO3825.
ypj:CH55_3190.
ypk:y0405.
ypl:CH46_1241.
ypm:YP_3223.
ypv:BZ15_3891.
ypw:CH59_1760.

Phylogenomic databases

eggNOGiCOG3075.
HOGENOMiHOG000278489.
KOiK00112.
OMAiDVFEVPM.
OrthoDBiEOG6K6V62.

Enzyme and pathway databases

UniPathwayiUPA00618; UER00673.
BioCyciYPES214092:GKDD-3796-MONOMER.

Family and domain databases

HAMAPiMF_00753. Glycerol3P_GlpB.
InterProiIPR003953. FAD_bind_dom.
IPR009158. G3P_DH_GlpB_su.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMsiTIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiGLPB_YERPE
AccessioniPrimary (citable) accession number: Q8ZAH6
Secondary accession number(s): Q0WAI5, Q8CWI2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2002
Last modified: July 22, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.