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Protein

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Gene

glpB

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.UniRule annotation

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FMNUniRule annotation

Pathwayi: glycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB), Anaerobic glycerol-3-phosphate dehydrogenase subunit B (glpB)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN

Enzyme and pathway databases

UniPathwayiUPA00618; UER00673

Names & Taxonomyi

Protein namesi
Recommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit BUniRule annotation (EC:1.1.5.3UniRule annotation)
Short name:
Anaerobic G-3-P dehydrogenase subunit BUniRule annotation
Short name:
Anaerobic G3Pdhase BUniRule annotation
Gene namesi
Name:glpBUniRule annotation
Ordered Locus Names:YPO3825, y0405, YP_3223
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002045711 – 424Anaerobic glycerol-3-phosphate dehydrogenase subunit BAdd BLAST424

Proteomic databases

PaxDbiQ8ZAH6

Interactioni

Subunit structurei

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.UniRule annotation

Protein-protein interaction databases

STRINGi187410.y0405

Structurei

3D structure databases

ProteinModelPortaliQ8ZAH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anaerobic G-3-P dehydrogenase subunit B family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KJ0 Bacteria
COG3075 LUCA
HOGENOMiHOG000278489
KOiK00112
OMAiVAINAQC

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00753 Glycerol3P_GlpB, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR009158 G3P_DH_GlpB_su
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PIRSFiPIRSF000141 Anaerobic_G3P_dh, 1 hit
SUPFAMiSSF51905 SSF51905, 3 hits
TIGRFAMsiTIGR03378 glycerol3P_GlpB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZAH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFDVIIIGG GLAGLACGIR LAEQGKYCAI VSSGQNALHF SSGSLDLLAK
60 70 80 90 100
LPDGQAVSQP LSALSALAEL APEHPYSKMR NITQLDELVQ EAEALLRRCG
110 120 130 140 150
LDIVGSSAEN HLRLTPLGSC RPTWLSLADI PVAPLNGPLP WQRVAVIGIE
160 170 180 190 200
GFLDFQPQMV ASALQDQGID ATADYLHLPA LDRLRDNPSE FRAVNIARIL
210 220 230 240 250
DLPENRQPLA DELSRLSSTA EMILLPACIG LDKSAPLDAL RAVVGKPIQL
260 270 280 290 300
LPTLPPSLLG MRLHQALRHR FQQLGGLVMP GDAVLRAELV DNRITGLYSR
310 320 330 340 350
NHGDIPLRAA QMVLASGSFF SNGLVATFDK IYEPILDLDI LSLPHRADWS
360 370 380 390 400
HSNLFAPQPY LQFGVNTDNH LRPLRGGVAL ENLHAIGAVL GGYDPLQQGC
410 420
GAGVSLTSAV FVAEQIISEM AVTL
Length:424
Mass (Da):45,506
Last modified:March 1, 2002 - v1
Checksum:iCEC65C3081A809E7
GO

Sequence cautioni

The sequence AAM83994 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAS63391 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL22412.1
AE009952 Genomic DNA Translation: AAM83994.1 Different initiation.
AE017042 Genomic DNA Translation: AAS63391.1 Different initiation.
PIRiAI0465
RefSeqiWP_002211492.1, NZ_PDBR01000036.1
YP_002348703.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM83994; AAM83994; y0405
AAS63391; AAS63391; YP_3223
GeneIDi1176660
KEGGiype:YPO3825
ypk:y0405
ypm:YP_3223
PATRICifig|214092.21.peg.4346

Similar proteinsi

Entry informationi

Entry nameiGLPB_YERPE
AccessioniPrimary (citable) accession number: Q8ZAH6
Secondary accession number(s): Q0WAI5, Q8CWI2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health