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Q8ZA84

- CAPP_YERPE

UniProt

Q8ZA84 - CAPP_YERPE

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, YPO3929, y0308, YP_3121
Organism
Yersinia pestis
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371 By similarity
Active sitei545 – 5451 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3906-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:YPO3929, y0308, YP_3121
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878878Phosphoenolpyruvate carboxylaseUniRule annotation
PRO_0000166654Add
BLAST

Proteomic databases

PRIDEiQ8ZA84.

Interactioni

Protein-protein interaction databases

IntActiQ8ZA84. 6 interactions.
STRINGi214092.YPO3929.

Structurei

3D structure databases

ProteinModelPortaliQ8ZA84.
SMRiQ8ZA84. Positions 4-878.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiISCQHYR.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZA84-1 [UniParc]FASTAAdd to Basket

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MNEQYSAMRS NVSMLGTLLG DTIKEALGEH ILDRVETIRK LSKSSRAGNE    50
ASRQELLTTL QNLSNDELLP VARAFSQFLN LTNTAEQYHS ISPHGEAASN 100
PEALAQLFTR LKDKKLSDQD MRSAVDDLSI ELVLTAHPTE ITRRTLIHKL 150
VEVNTCLSQL DHNDLADYER NKIMRRLRQL VAQSWHTDEI RKLRPSPVDE 200
AKWGFAVVEN SLWEGVPAFL REFNEQLENS LDYRLPVEAV PIRFTSWMGG 250
DRDGNPNVTA EITRHVLLLS RWKATDLFLR DIQVLVSELS MSECTPELRE 300
LAGGEEVLEP YRQLMKNVRT QLTNTQAYLE ARLKGERVLP PHDLLVSNDQ 350
LWEPLYACYQ SLKACGMEII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR 400
HTDAIAELTR YLGLGDYESW SESDKQAFLV RELNSKRPLV PLKWEPSAET 450
QEVLETCRVI AEAPQGSIAA YVISMAKVPS DVLAVHLLLK EAGCPFTLPV 500
APLFETLDDL NNADDVMTQL LGIDWYRGLI QGKQMVMIGY SDSAKDAGVM 550
AASWAQYRAQ DALIKTCEKA GITLTLFHGR GGSIGRGGAP AHAALLSQPP 600
GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYAGAILEA NLLPPPEPKK 650
EWIEVMDLLS DASCDMYRSY VRENPEFVRY FRAATPELEL GKLPLGSRPA 700
KRRPDGGVES LRAIPWIFAW TQNRLMLPAW LGAGAGLQRA IDAGKQDVLA 750
TMCRDWPFFS TRIGMLEMVF AKADLWLAEY YDQRLVDKSL WPLGQQLRDQ 800
LAADIKVVLA IANDDHLMAD LPWIAESIAL RNVYTDPLNV LQAELLHRSR 850
QQEHPDACVE QALMVTIAGV AAGMRNTG 878
Length:878
Mass (Da):98,324
Last modified:March 1, 2002 - v1
Checksum:iF57CE8ABD26287B4
GO

Sequence cautioni

The sequence AAM83899.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAS63291.1 differs from that shown. Reason: Erroneous initiation.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti669 – 6691S → N in AAS63291. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL22512.1.
AE009952 Genomic DNA. Translation: AAM83899.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63291.1. Different initiation.
PIRiAE0478.
RefSeqiYP_002348802.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM83899; AAM83899; y0308.
AAS63291; AAS63291; YP_3121.
GeneIDi1176770.
KEGGiype:YPO3929.
PATRICi18598095. VBIYerPes7843_4705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL22512.1 .
AE009952 Genomic DNA. Translation: AAM83899.1 . Different initiation.
AE017042 Genomic DNA. Translation: AAS63291.1 . Different initiation.
PIRi AE0478.
RefSeqi YP_002348802.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8ZA84.
SMRi Q8ZA84. Positions 4-878.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8ZA84. 6 interactions.
STRINGi 214092.YPO3929.

Proteomic databases

PRIDEi Q8ZA84.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM83899 ; AAM83899 ; y0308 .
AAS63291 ; AAS63291 ; YP_3121 .
GeneIDi 1176770.
KEGGi ype:YPO3929.
PATRICi 18598095. VBIYerPes7843_4705.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ISCQHYR.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-3906-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiCAPP_YERPE
AccessioniPrimary (citable) accession number: Q8ZA84
Secondary accession number(s): Q0WA86
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi