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Q8ZA84

- CAPP_YERPE

UniProt

Q8ZA84 - CAPP_YERPE

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3906-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:YPO3929, y0308, YP_3121
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878878Phosphoenolpyruvate carboxylasePRO_0000166654Add
BLAST

Proteomic databases

PRIDEiQ8ZA84.

Interactioni

Protein-protein interaction databases

IntActiQ8ZA84. 6 interactions.
STRINGi214092.YPO3929.

Structurei

3D structure databases

ProteinModelPortaliQ8ZA84.
SMRiQ8ZA84. Positions 4-878.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiISCQHYR.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZA84-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNEQYSAMRS NVSMLGTLLG DTIKEALGEH ILDRVETIRK LSKSSRAGNE
60 70 80 90 100
ASRQELLTTL QNLSNDELLP VARAFSQFLN LTNTAEQYHS ISPHGEAASN
110 120 130 140 150
PEALAQLFTR LKDKKLSDQD MRSAVDDLSI ELVLTAHPTE ITRRTLIHKL
160 170 180 190 200
VEVNTCLSQL DHNDLADYER NKIMRRLRQL VAQSWHTDEI RKLRPSPVDE
210 220 230 240 250
AKWGFAVVEN SLWEGVPAFL REFNEQLENS LDYRLPVEAV PIRFTSWMGG
260 270 280 290 300
DRDGNPNVTA EITRHVLLLS RWKATDLFLR DIQVLVSELS MSECTPELRE
310 320 330 340 350
LAGGEEVLEP YRQLMKNVRT QLTNTQAYLE ARLKGERVLP PHDLLVSNDQ
360 370 380 390 400
LWEPLYACYQ SLKACGMEII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR
410 420 430 440 450
HTDAIAELTR YLGLGDYESW SESDKQAFLV RELNSKRPLV PLKWEPSAET
460 470 480 490 500
QEVLETCRVI AEAPQGSIAA YVISMAKVPS DVLAVHLLLK EAGCPFTLPV
510 520 530 540 550
APLFETLDDL NNADDVMTQL LGIDWYRGLI QGKQMVMIGY SDSAKDAGVM
560 570 580 590 600
AASWAQYRAQ DALIKTCEKA GITLTLFHGR GGSIGRGGAP AHAALLSQPP
610 620 630 640 650
GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYAGAILEA NLLPPPEPKK
660 670 680 690 700
EWIEVMDLLS DASCDMYRSY VRENPEFVRY FRAATPELEL GKLPLGSRPA
710 720 730 740 750
KRRPDGGVES LRAIPWIFAW TQNRLMLPAW LGAGAGLQRA IDAGKQDVLA
760 770 780 790 800
TMCRDWPFFS TRIGMLEMVF AKADLWLAEY YDQRLVDKSL WPLGQQLRDQ
810 820 830 840 850
LAADIKVVLA IANDDHLMAD LPWIAESIAL RNVYTDPLNV LQAELLHRSR
860 870
QQEHPDACVE QALMVTIAGV AAGMRNTG
Length:878
Mass (Da):98,324
Last modified:March 1, 2002 - v1
Checksum:iF57CE8ABD26287B4
GO

Sequence cautioni

The sequence AAM83899.1 differs from that shown. Reason: Erroneous initiation.
The sequence AAS63291.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti669 – 6691S → N in AAS63291. (PubMed:15368893)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL22512.1.
AE009952 Genomic DNA. Translation: AAM83899.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63291.1. Different initiation.
PIRiAE0478.
RefSeqiYP_002348802.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM83899; AAM83899; y0308.
AAS63291; AAS63291; YP_3121.
GeneIDi1176770.
KEGGiype:YPO3929.
PATRICi18598095. VBIYerPes7843_4705.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590842 Genomic DNA. Translation: CAL22512.1 .
AE009952 Genomic DNA. Translation: AAM83899.1 . Different initiation.
AE017042 Genomic DNA. Translation: AAS63291.1 . Different initiation.
PIRi AE0478.
RefSeqi YP_002348802.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8ZA84.
SMRi Q8ZA84. Positions 4-878.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8ZA84. 6 interactions.
STRINGi 214092.YPO3929.

Proteomic databases

PRIDEi Q8ZA84.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM83899 ; AAM83899 ; y0308 .
AAS63291 ; AAS63291 ; YP_3121 .
GeneIDi 1176770.
KEGGi ype:YPO3929.
PATRICi 18598095. VBIYerPes7843_4705.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ISCQHYR.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-3906-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiCAPP_YERPE
AccessioniPrimary (citable) accession number: Q8ZA84
Secondary accession number(s): Q0WA86
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3