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Q8ZA84

- CAPP_YERPE

UniProt

Q8ZA84 - CAPP_YERPE

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei137 – 1371UniRule annotation
    Active sitei545 – 5451UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-3906-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:YPO3929, y0308, YP_3121
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 878878Phosphoenolpyruvate carboxylasePRO_0000166654Add
    BLAST

    Proteomic databases

    PRIDEiQ8ZA84.

    Interactioni

    Protein-protein interaction databases

    IntActiQ8ZA84. 6 interactions.
    STRINGi214092.YPO3929.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZA84.
    SMRiQ8ZA84. Positions 4-878.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238648.
    KOiK01595.
    OMAiISCQHYR.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZA84-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNEQYSAMRS NVSMLGTLLG DTIKEALGEH ILDRVETIRK LSKSSRAGNE    50
    ASRQELLTTL QNLSNDELLP VARAFSQFLN LTNTAEQYHS ISPHGEAASN 100
    PEALAQLFTR LKDKKLSDQD MRSAVDDLSI ELVLTAHPTE ITRRTLIHKL 150
    VEVNTCLSQL DHNDLADYER NKIMRRLRQL VAQSWHTDEI RKLRPSPVDE 200
    AKWGFAVVEN SLWEGVPAFL REFNEQLENS LDYRLPVEAV PIRFTSWMGG 250
    DRDGNPNVTA EITRHVLLLS RWKATDLFLR DIQVLVSELS MSECTPELRE 300
    LAGGEEVLEP YRQLMKNVRT QLTNTQAYLE ARLKGERVLP PHDLLVSNDQ 350
    LWEPLYACYQ SLKACGMEII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR 400
    HTDAIAELTR YLGLGDYESW SESDKQAFLV RELNSKRPLV PLKWEPSAET 450
    QEVLETCRVI AEAPQGSIAA YVISMAKVPS DVLAVHLLLK EAGCPFTLPV 500
    APLFETLDDL NNADDVMTQL LGIDWYRGLI QGKQMVMIGY SDSAKDAGVM 550
    AASWAQYRAQ DALIKTCEKA GITLTLFHGR GGSIGRGGAP AHAALLSQPP 600
    GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYAGAILEA NLLPPPEPKK 650
    EWIEVMDLLS DASCDMYRSY VRENPEFVRY FRAATPELEL GKLPLGSRPA 700
    KRRPDGGVES LRAIPWIFAW TQNRLMLPAW LGAGAGLQRA IDAGKQDVLA 750
    TMCRDWPFFS TRIGMLEMVF AKADLWLAEY YDQRLVDKSL WPLGQQLRDQ 800
    LAADIKVVLA IANDDHLMAD LPWIAESIAL RNVYTDPLNV LQAELLHRSR 850
    QQEHPDACVE QALMVTIAGV AAGMRNTG 878
    Length:878
    Mass (Da):98,324
    Last modified:March 1, 2002 - v1
    Checksum:iF57CE8ABD26287B4
    GO

    Sequence cautioni

    The sequence AAM83899.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAS63291.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti669 – 6691S → N in AAS63291. (PubMed:15368893)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL22512.1.
    AE009952 Genomic DNA. Translation: AAM83899.1. Different initiation.
    AE017042 Genomic DNA. Translation: AAS63291.1. Different initiation.
    PIRiAE0478.
    RefSeqiYP_002348802.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM83899; AAM83899; y0308.
    AAS63291; AAS63291; YP_3121.
    GeneIDi1176770.
    KEGGiype:YPO3929.
    PATRICi18598095. VBIYerPes7843_4705.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590842 Genomic DNA. Translation: CAL22512.1 .
    AE009952 Genomic DNA. Translation: AAM83899.1 . Different initiation.
    AE017042 Genomic DNA. Translation: AAS63291.1 . Different initiation.
    PIRi AE0478.
    RefSeqi YP_002348802.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q8ZA84.
    SMRi Q8ZA84. Positions 4-878.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q8ZA84. 6 interactions.
    STRINGi 214092.YPO3929.

    Proteomic databases

    PRIDEi Q8ZA84.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM83899 ; AAM83899 ; y0308 .
    AAS63291 ; AAS63291 ; YP_3121 .
    GeneIDi 1176770.
    KEGGi ype:YPO3929.
    PATRICi 18598095. VBIYerPes7843_4705.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238648.
    KOi K01595.
    OMAi ISCQHYR.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci YPES214092:GKDD-3906-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiCAPP_YERPE
    AccessioniPrimary (citable) accession number: Q8ZA84
    Secondary accession number(s): Q0WA86
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3