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Protein

Glycogen synthase

Gene

glgA

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3914-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:YPO3939, y3889, YP_3301
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_0000188666Add
BLAST

Proteomic databases

PRIDEiQ8ZA78.

Interactioni

Protein-protein interaction databases

STRINGi214092.YPO3939.

Structurei

3D structure databases

ProteinModelPortaliQ8ZA78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZA78-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRVLHVCSEL FPLLKTGGLA DVIGALPAAQ LAEGADVRII LPAFPDLRRG
60 70 80 90 100
IPETVLVREI DTFAGRVALR YGHYRGIGIY LIDAPALYDR AGSPYHDASL
110 120 130 140 150
YAYSDNYLRF ALLGWMACEL ACGLDGYWRP EVVHAHDWHA GLTCAYLAAR
160 170 180 190 200
GRPARSVFTV HNLAYQGLFS ADHLSELHLP AEFFQIYGLE FYGQISYLKA
210 220 230 240 250
GLFFADHVTT VSPTYAKEIT QPAFGYGMEG LLQALARQGR LTGILNGVDS
260 270 280 290 300
DIWDPQSDTL LPTRYDAENL QAKAINKTHL QTAMGLQLAE NKPIFAVVSR
310 320 330 340 350
LTVQKGLDLV LEALPELLAL GGQLVVLGSG DATLQEAFLA AAAEHSGQVG
360 370 380 390 400
VQIGYHEAFS HRIIAGSDVI LVPSRFEPCG LTQLYGLKYG TLPLVRHTGG
410 420 430 440 450
LADTVVDCAL ENLADGSASG FVFNECEAQA LVKAIRRAFV LWSRPKHWRH
460 470
VQRHAMRLDF GWQLAAVDYL SLYRRL
Length:476
Mass (Da):52,276
Last modified:March 5, 2002 - v1
Checksum:iA057EA3FEC5B6800
GO

Sequence cautioni

The sequence AAM87434.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAS63466.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22520.1.
AE009952 Genomic DNA. Translation: AAM87434.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63466.1. Different initiation.
PIRiAE0479.
RefSeqiNP_671183.1. NC_004088.1.
NP_994589.1. NC_005810.1.
YP_002348810.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM87434; AAM87434; y3889.
AAS63466; AAS63466; YP_3301.
GeneIDi1148836.
1176778.
2764197.
KEGGiype:YPO3939.
ypk:y3889.
ypm:YP_3301.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22520.1.
AE009952 Genomic DNA. Translation: AAM87434.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63466.1. Different initiation.
PIRiAE0479.
RefSeqiNP_671183.1. NC_004088.1.
NP_994589.1. NC_005810.1.
YP_002348810.1. NC_003143.1.

3D structure databases

ProteinModelPortaliQ8ZA78.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi214092.YPO3939.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Proteomic databases

PRIDEiQ8ZA78.

Protocols and materials databases

DNASUi1148836.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM87434; AAM87434; y3889.
AAS63466; AAS63466; YP_3301.
GeneIDi1148836.
1176778.
2764197.
KEGGiype:YPO3939.
ypk:y3889.
ypm:YP_3301.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciYPES214092:GKDD-3914-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiGLGA_YERPE
AccessioniPrimary (citable) accession number: Q8ZA78
Secondary accession number(s): Q0WA78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: January 7, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.