Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8ZA75

- GLGB_YERPE

UniProt

Q8ZA75 - GLGB_YERPE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei405 – 4051NucleophileUniRule annotation
Active sitei458 – 4581Proton donorUniRule annotation

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3917-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:YPO3942, y3886, YP_3304
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7277271,4-alpha-glucan branching enzyme GlgBPRO_0000188770Add
BLAST

Proteomic databases

PRIDEiQ8ZA75.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi214092.YPO3942.

Structurei

3D structure databases

ProteinModelPortaliQ8ZA75.
SMRiQ8ZA75. Positions 117-726.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiPIGVAYK.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZA75-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVLPDRQVI NQLISGHYGD PFSILGMHET SQGLQICALL PDAREVWLVE
60 70 80 90 100
TENGRRIAQL TLEDPRGFFI AQLTRRKKSF RYQFAVTWQE NPQIIEDPYR
110 120 130 140 150
FGPLLQDIDS WLLAEGTHLR PYERLGAHLM SLDGVSGVSF AVWAPNAQRV
160 170 180 190 200
SVVGDFNFWD GRRHPMRLRR ENGIWELFLP GIEAGQLYKF EIIDCHGQVR
210 220 230 240 250
LKADPYAFEA QMRPETASLI SPLPDVVKSS AARQKANDLC SPVSIYEVHL
260 270 280 290 300
GSWRRHTDNN FWLSYRELAD QLVEYVKYMG FTHVELLPIN EHPFDGSWGY
310 320 330 340 350
QPLGLYAPTR RYGTPEDFKA FVAKFHQAGI NVILDWVPGH FPSDEHGLST
360 370 380 390 400
FDGTALYEYA DPREGYHQDW NTLIYNYGRN EVRNYLAGNA FYWMERFGID
410 420 430 440 450
ALRIDAVASM IYRDYSRAEG QWVPNYYGGR ENLEAIAFLR YTNKTIGVER
460 470 480 490 500
PGSVTMAEES TDFPGVTLPP DIGGLGFNYK WNMGWMHDTL NYMQCDPVHR
510 520 530 540 550
KYHHNLMTFG MLYAYTENFI LPLSHDEVVH GKRSILDRMP GDAWQKFANL
560 570 580 590 600
RAYYAFMWAH PGKKLLFMGC EFAQGREWNF ETSLDWHLLD DENGWHSGVQ
610 620 630 640 650
RLVRDLNHCY RQYAPLYEWD YQPAGFEWLV VDDHENSVFA FLRRDAEGHE
660 670 680 690 700
LIAISNFTPV PRYHYRVGIP QGGHYREVLN SDSAFYCGSN LGNQGGIDSH
710 720
HVRSHNHEHS LLLTLPPLAT IYLLREN
Length:727
Mass (Da):84,135
Last modified:March 1, 2002 - v1
Checksum:i40D16ED7083B33D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22523.1.
AE009952 Genomic DNA. Translation: AAM87431.1.
AE017042 Genomic DNA. Translation: AAS63469.1.
PIRiAH0479.
RefSeqiNP_671180.1. NC_004088.1.
NP_994592.1. NC_005810.1.
YP_002348813.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM87431; AAM87431; y3886.
AAS63469; AAS63469; YP_3304.
GeneIDi1148833.
1176781.
2764145.
KEGGiype:YPO3942.
ypk:y3886.
ypm:YP_3304.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22523.1 .
AE009952 Genomic DNA. Translation: AAM87431.1 .
AE017042 Genomic DNA. Translation: AAS63469.1 .
PIRi AH0479.
RefSeqi NP_671180.1. NC_004088.1.
NP_994592.1. NC_005810.1.
YP_002348813.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8ZA75.
SMRi Q8ZA75. Positions 117-726.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO3942.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Proteomic databases

PRIDEi Q8ZA75.

Protocols and materials databases

DNASUi 1148833.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM87431 ; AAM87431 ; y3886 .
AAS63469 ; AAS63469 ; YP_3304 .
GeneIDi 1148833.
1176781.
2764145.
KEGGi ype:YPO3942.
ypk:y3886.
ypm:YP_3304.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi PIGVAYK.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci YPES214092:GKDD-3917-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiGLGB_YERPE
AccessioniPrimary (citable) accession number: Q8ZA75
Secondary accession number(s): Q0WA75
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3