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Q8Z9U4

- RNPA_YERPE

UniProt

Q8Z9U4 - RNPA_YERPE

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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciYPES214092:GKDD-4064-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:YPO4101, y4115, YP_4008
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 119119Ribonuclease P protein componentPRO_0000198571Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi214092.YPO4101.

Structurei

3D structure databases

ProteinModelPortaliQ8Z9U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0594.
HOGENOMiHOG000266301.
KOiK03536.
OMAiPPMDFVV.
OrthoDBiEOG6C01C6.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Z9U4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKLAFPREL RLLTPSHFTF VFQQPQRAGT PQITILGRLN ELGHPRIGLT
60 70 80 90 100
VAKKHVKRAH ERNRIKRLTR ESFRLHQHAL PSMDFVVLVK KGVADLDNRA
110
LTEALEKLWR RHCRQAPAS
Length:119
Mass (Da):13,800
Last modified:March 1, 2002 - v1
Checksum:i20C70729B34B5D24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22669.1.
AE009952 Genomic DNA. Translation: AAM87657.1.
AE017042 Genomic DNA. Translation: AAS64147.1.
PIRiAI0497.
RefSeqiNP_671406.1. NC_004088.1.
NP_995270.1. NC_005810.1.
YP_002348952.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM87657; AAM87657; y4115.
AAS64147; AAS64147; YP_4008.
GeneIDi1149062.
1176929.
2764823.
KEGGiype:YPO4101.
ypk:y4115.
ypm:YP_4008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL22669.1 .
AE009952 Genomic DNA. Translation: AAM87657.1 .
AE017042 Genomic DNA. Translation: AAS64147.1 .
PIRi AI0497.
RefSeqi NP_671406.1. NC_004088.1.
NP_995270.1. NC_005810.1.
YP_002348952.1. NC_003143.1.

3D structure databases

ProteinModelPortali Q8Z9U4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214092.YPO4101.

Protocols and materials databases

DNASUi 1149062.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM87657 ; AAM87657 ; y4115 .
AAS64147 ; AAS64147 ; YP_4008 .
GeneIDi 1149062.
1176929.
2764823.
KEGGi ype:YPO4101.
ypk:y4115.
ypm:YP_4008.

Phylogenomic databases

eggNOGi COG0594.
HOGENOMi HOG000266301.
KOi K03536.
OMAi PPMDFVV.
OrthoDBi EOG6C01C6.

Enzyme and pathway databases

BioCyci YPES214092:GKDD-4064-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
ProDomi PD003629. Ribonuclease_P. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiRNPA_YERPE
AccessioniPrimary (citable) accession number: Q8Z9U4
Secondary accession number(s): Q0W9T6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3