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Q8Z9R7

- Q8Z9R7_SALTI

UniProt

Q8Z9R7 - Q8Z9R7_SALTI

Protein
Submitted name:

Aspartokinase I

Gene

thrA

Organism
Salmonella typhi
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 100 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. amino acid binding Source: InterPro
    2. aspartate kinase activity Source: InterPro
    3. homoserine dehydrogenase activity Source: InterPro
    4. NADP binding Source: InterPro

    GO - Biological processi

    1. aspartate family amino acid biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aspartokinase IImported
    Submitted name:
    Aspartokinase I/homoserine dehydrogenase IImported
    Gene namesi
    Name:thrAImported
    Ordered Locus Names:STY0002Imported, t0002Imported
    OrganismiSalmonella typhiImported
    Taxonomic identifieri90370 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000002670: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi220341.STY0002.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000271593.
    KOiK12524.
    OMAiYIFGMLD.
    OrthoDBiEOG6M0T34.

    Family and domain databases

    Gene3Di3.40.1160.10. 2 hits.
    3.40.50.720. 1 hit.
    InterProiIPR002912. ACT_dom.
    IPR001048. Asp/Glu/Uridylate_kinase.
    IPR005106. Asp/hSer_DH_NAD-bd.
    IPR001341. Asp_kinase_dom.
    IPR018042. Aspartate_kinase_CS.
    IPR011147. Bifunc_aspartokin/hSer_DH.
    IPR027795. GATS-like_ACT_dom.
    IPR001342. HDH_cat.
    IPR019811. HDH_CS.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00696. AA_kinase. 1 hit.
    PF13840. ACT_7. 2 hits.
    PF00742. Homoserine_dh. 1 hit.
    PF03447. NAD_binding_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000727. ThrA. 1 hit.
    SUPFAMiSSF53633. SSF53633. 1 hit.
    TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
    PROSITEiPS51671. ACT. 2 hits.
    PS00324. ASPARTOKINASE. 1 hit.
    PS01042. HOMOSER_DHGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8Z9R7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRVLKFGGTS VANAERFLRV ADILESNSRQ GQVATVLSAP AKITNHLVAM    50
    IEKTIGGQDA LPNISDAERI FSDLLAGLAS AQPGFPLARL KMVVEQEFAQ 100
    IKHVLHGISL LGQCPDSINA ALICRGEKMS IAIMAGLLEA RGHRVTVIDP 150
    VEKLLAVGHY LESTVDIAES TRRIAASQIP ADHMILMAGF TAGNEKGELV 200
    VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV PDARLLKSMS 250
    YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASSD 300
    DDNLPVKGIS NLNNMAMFSV SGPGMKGMIG MAARVFAAMS RAGISVVLIT 350
    QSSSEYSISF CVPQSDCARA RRAMQDEFYL ELKEGLLEPL AVTERLAIIS 400
    VVGDGMRTLR GISAKFFAAL ARANINIVAI AQGSSERSIS VVVNNDDATT 450
    GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL LEQLKRQQTW LKNKHIDLRV 500
    CGVANSKALL TNVHGLNLDN WQAELAQANA PFNLGRLIRL VKEYHLLNPV 550
    IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRFAAAQSR 600
    RKFLYDTNVG AGLPVIENLQ NLLNAGDELQ KFSGILSGSL SFIFGKLEEG 650
    MSLSQATALA REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELSDIV 700
    IEPVLPDEFD ASGDVTAFMA HLPQLDDAFA ARVAKARDEG KVLRYVGNIE 750
    EDGVCRVKIA EVDGNDPLFK VKNGENALAF YSHYYQPLPL VLRGYGAGND 800
    VTAAGVFADL LRTLSWKLGV 820
    Length:820
    Mass (Da):88,712
    Last modified:March 1, 2002 - v1
    Checksum:iED6CDB2F6F01AC67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014613 Genomic DNA. Translation: AAO67736.1.
    AL513382 Genomic DNA. Translation: CAD01155.1.
    RefSeqiNP_454612.1. NC_003198.1.
    NP_803887.1. NC_004631.1.

    Genome annotation databases

    EnsemblBacteriaiAAO67736; AAO67736; t0002.
    CAD01155; CAD01155; CAD01155.
    GeneIDi1246513.
    KEGGisty:STY0002.
    PATRICi18537815. VBISalEnt120419_0001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE014613 Genomic DNA. Translation: AAO67736.1 .
    AL513382 Genomic DNA. Translation: CAD01155.1 .
    RefSeqi NP_454612.1. NC_003198.1.
    NP_803887.1. NC_004631.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 220341.STY0002.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO67736 ; AAO67736 ; t0002 .
    CAD01155 ; CAD01155 ; CAD01155 .
    GeneIDi 1246513.
    KEGGi sty:STY0002.
    PATRICi 18537815. VBISalEnt120419_0001.

    Phylogenomic databases

    HOGENOMi HOG000271593.
    KOi K12524.
    OMAi YIFGMLD.
    OrthoDBi EOG6M0T34.

    Family and domain databases

    Gene3Di 3.40.1160.10. 2 hits.
    3.40.50.720. 1 hit.
    InterProi IPR002912. ACT_dom.
    IPR001048. Asp/Glu/Uridylate_kinase.
    IPR005106. Asp/hSer_DH_NAD-bd.
    IPR001341. Asp_kinase_dom.
    IPR018042. Aspartate_kinase_CS.
    IPR011147. Bifunc_aspartokin/hSer_DH.
    IPR027795. GATS-like_ACT_dom.
    IPR001342. HDH_cat.
    IPR019811. HDH_CS.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00696. AA_kinase. 1 hit.
    PF13840. ACT_7. 2 hits.
    PF00742. Homoserine_dh. 1 hit.
    PF03447. NAD_binding_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000727. ThrA. 1 hit.
    SUPFAMi SSF53633. SSF53633. 1 hit.
    TIGRFAMsi TIGR00657. asp_kinases. 1 hit.
    PROSITEi PS51671. ACT. 2 hits.
    PS00324. ASPARTOKINASE. 1 hit.
    PS01042. HOMOSER_DHGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CT18Imported.
    2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
      Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
      J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700931 / Ty2Imported and Ty2Imported.

    Entry informationi

    Entry nameiQ8Z9R7_SALTI
    AccessioniPrimary (citable) accession number: Q8Z9R7
    Secondary accession number(s): Q7CBW4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 100 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3