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Q8Z9R7

- Q8Z9R7_SALTI

UniProt

Q8Z9R7 - Q8Z9R7_SALTI

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Protein
Submitted name: Aspartokinase I
Gene
thrA, STY0002, t0002
Organism
Salmonella typhi
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. NADP binding Source: InterPro
  2. amino acid binding Source: InterPro
  3. aspartate kinase activity Source: InterPro
  4. homoserine dehydrogenase activity Source: InterPro

GO - Biological processi

  1. aspartate family amino acid biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Aspartokinase IImported
Submitted name:
Aspartokinase I/homoserine dehydrogenase IImported
Gene namesi
Name:thrAImported
Ordered Locus Names:STY0002Imported, t0002Imported
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000541: Assembled contig, UP000000541: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi220341.STY0002.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000271593.
KOiK12524.
OMAiYIFGMLD.
OrthoDBiEOG6M0T34.

Family and domain databases

Gene3Di3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR027795. GATS-like_ACT_dom.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 2 hits.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000727. ThrA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
PROSITEiPS51671. ACT. 2 hits.
PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Z9R7-1 [UniParc]FASTAAdd to Basket

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MRVLKFGGTS VANAERFLRV ADILESNSRQ GQVATVLSAP AKITNHLVAM    50
IEKTIGGQDA LPNISDAERI FSDLLAGLAS AQPGFPLARL KMVVEQEFAQ 100
IKHVLHGISL LGQCPDSINA ALICRGEKMS IAIMAGLLEA RGHRVTVIDP 150
VEKLLAVGHY LESTVDIAES TRRIAASQIP ADHMILMAGF TAGNEKGELV 200
VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV PDARLLKSMS 250
YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASSD 300
DDNLPVKGIS NLNNMAMFSV SGPGMKGMIG MAARVFAAMS RAGISVVLIT 350
QSSSEYSISF CVPQSDCARA RRAMQDEFYL ELKEGLLEPL AVTERLAIIS 400
VVGDGMRTLR GISAKFFAAL ARANINIVAI AQGSSERSIS VVVNNDDATT 450
GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL LEQLKRQQTW LKNKHIDLRV 500
CGVANSKALL TNVHGLNLDN WQAELAQANA PFNLGRLIRL VKEYHLLNPV 550
IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRFAAAQSR 600
RKFLYDTNVG AGLPVIENLQ NLLNAGDELQ KFSGILSGSL SFIFGKLEEG 650
MSLSQATALA REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELSDIV 700
IEPVLPDEFD ASGDVTAFMA HLPQLDDAFA ARVAKARDEG KVLRYVGNIE 750
EDGVCRVKIA EVDGNDPLFK VKNGENALAF YSHYYQPLPL VLRGYGAGND 800
VTAAGVFADL LRTLSWKLGV 820
Length:820
Mass (Da):88,712
Last modified:March 1, 2002 - v1
Checksum:iED6CDB2F6F01AC67
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014613 Genomic DNA. Translation: AAO67736.1.
AL513382 Genomic DNA. Translation: CAD01155.1.
RefSeqiNP_454612.1. NC_003198.1.
NP_803887.1. NC_004631.1.

Genome annotation databases

EnsemblBacteriaiAAO67736; AAO67736; t0002.
CAD01155; CAD01155; CAD01155.
GeneIDi1246513.
KEGGisty:STY0002.
PATRICi18537815. VBISalEnt120419_0001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE014613 Genomic DNA. Translation: AAO67736.1 .
AL513382 Genomic DNA. Translation: CAD01155.1 .
RefSeqi NP_454612.1. NC_003198.1.
NP_803887.1. NC_004631.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220341.STY0002.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO67736 ; AAO67736 ; t0002 .
CAD01155 ; CAD01155 ; CAD01155 .
GeneIDi 1246513.
KEGGi sty:STY0002.
PATRICi 18537815. VBISalEnt120419_0001.

Phylogenomic databases

HOGENOMi HOG000271593.
KOi K12524.
OMAi YIFGMLD.
OrthoDBi EOG6M0T34.

Family and domain databases

Gene3Di 3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProi IPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR027795. GATS-like_ACT_dom.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
PF13840. ACT_7. 2 hits.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000727. ThrA. 1 hit.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00657. asp_kinases. 1 hit.
PROSITEi PS51671. ACT. 2 hits.
PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18Imported.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2 and Ty2Imported.

Entry informationi

Entry nameiQ8Z9R7_SALTI
AccessioniPrimary (citable) accession number: Q8Z9R7
Secondary accession number(s): Q7CBW4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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