Q8Z9R7 (Q8Z9R7_SALTI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aspartokinase I EMBL AAO67736.1

Submitted name:
Aspartokinase I/homoserine dehydrogenase I EMBL CAD01155.1

Gene names

Name:	thrA EMBL AAO67736.1
Ordered Locus Names:	STY0002 EMBL CAD01155.1, t0002 EMBL AAO67736.1

Organism

Salmonella typhi [Complete proteome] [HAMAP] EMBL CAD01155.1

Taxonomic identifier

90370 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I

Protein attributes

Sequence length	820 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Kinase EMBL CAD01155.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aspartate family amino acid biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro aspartate kinase activity Inferred from electronic annotation. Source: InterPro homoserine dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8Z9R7 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: ED6CDB2F6F01AC67	FASTA	820	88,712
	10 20 30 40 50 60 MRVLKFGGTS VANAERFLRV ADILESNSRQ GQVATVLSAP AKITNHLVAM IEKTIGGQDA 70 80 90 100 110 120 LPNISDAERI FSDLLAGLAS AQPGFPLARL KMVVEQEFAQ IKHVLHGISL LGQCPDSINA 130 140 150 160 170 180 ALICRGEKMS IAIMAGLLEA RGHRVTVIDP VEKLLAVGHY LESTVDIAES TRRIAASQIP 190 200 210 220 230 240 ADHMILMAGF TAGNEKGELV VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV 250 260 270 280 290 300 PDARLLKSMS YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASSD 310 320 330 340 350 360 DDNLPVKGIS NLNNMAMFSV SGPGMKGMIG MAARVFAAMS RAGISVVLIT QSSSEYSISF 370 380 390 400 410 420 CVPQSDCARA RRAMQDEFYL ELKEGLLEPL AVTERLAIIS VVGDGMRTLR GISAKFFAAL 430 440 450 460 470 480 ARANINIVAI AQGSSERSIS VVVNNDDATT GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL 490 500 510 520 530 540 LEQLKRQQTW LKNKHIDLRV CGVANSKALL TNVHGLNLDN WQAELAQANA PFNLGRLIRL 550 560 570 580 590 600 VKEYHLLNPV IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRFAAAQSR 610 620 630 640 650 660 RKFLYDTNVG AGLPVIENLQ NLLNAGDELQ KFSGILSGSL SFIFGKLEEG MSLSQATALA 670 680 690 700 710 720 REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELSDIV IEPVLPDEFD ASGDVTAFMA 730 740 750 760 770 780 HLPQLDDAFA ARVAKARDEG KVLRYVGNIE EDGVCRVKIA EVDGNDPLFK VKNGENALAF 790 800 810 820 YSHYYQPLPL VLRGYGAGND VTAAGVFADL LRTLSWKLGV

References

[1]

"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18." Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:848-852(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CT18 EMBL CAD01155.1.

[2]

"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18." Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700931 / Ty2 and Ty2 EMBL AAO67736.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014613 Genomic DNA. Translation: AAO67736.1. AL627265 Genomic DNA. Translation: CAD01155.1.
RefSeq	NP_803887.1. NC_004631.1.
3D structure databases
HSSP	HSSP built from PDB template 1EBF based on UniProtKB P31116.
ModBase	Search...
Protein-protein interaction databases
STRING	220341.STY0002.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO67736; AAO67736; t0002. CAD01155; CAD01155; CAD01155.
GeneID	1066974.
KEGG	stt:t0002.
PATRIC	18537815. VBISalEnt120419_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000271593.
KO	K12524.
OMA	IFISQAS.
ProtClustDB	PRK09436.
Family and domain databases
Gene3D	3.40.1160.10. 2 hits. 3.40.50.720. 1 hit.
InterPro	IPR001048. Asp/Glu/Uridylate_kinase. IPR005106. Asp/hSer_DH_NAD-bd. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. IPR011147. Bifunc_aspartokin/hSer_DH. IPR001342. HDH_cat. IPR019811. HDH_CS. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00696. AA_kinase. 1 hit. PF00742. Homoserine_dh. 1 hit. PF03447. NAD_binding_3. 1 hit. [Graphical view]
PIRSF	PIRSF000727. ThrA. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00657. asp_kinases. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. PS01042. HOMOSER_DHGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8Z9R7_SALTI

Accession

Primary (citable) accession number: Q8Z9R7
Secondary accession number(s): Q7CBW4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)