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Q8Z8E5 (ATKB_SALTI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative potassium-transporting ATPase B chain
EC=3.6.3.12
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chain
Potassium-binding and translocating subunit B
Potassium-translocating ATPase B chain
Gene names
Name:kdpB
Ordered Locus Names:STY0746, t2170
OrganismSalmonella typhi [Complete proteome] [HAMAP]
Taxonomic identifier90370 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length569 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions By similarity. HAMAP-Rule MF_00285

Catalytic activity

ATP + H2O + K+(Out) = ADP + phosphate + K+(In). HAMAP-Rule MF_00285

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00285.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]

Caution

Could be the product of a pseudogene. Contains an internal 112 amino acid deletion relative to its orthologs.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 569569Putative potassium-transporting ATPase B chain HAMAP-Rule MF_00285
PRO_0000046132

Regions

Topological domain1 – 3636Cytoplasmic Potential
Transmembrane37 – 5923Helical; Potential
Topological domain60 – 623Periplasmic Potential
Transmembrane63 – 8523Helical; Potential
Topological domain86 – 464379Cytoplasmic Potential
Transmembrane465 – 48723Helical; Potential
Topological domain488 – 50114Periplasmic Potential
Transmembrane502 – 52120Helical; Potential
Topological domain522 – 54019Cytoplasmic Potential
Transmembrane541 – 56323Helical; Potential
Topological domain564 – 5696Periplasmic Potential

Sites

Active site19414-aspartylphosphate intermediate By similarity
Metal binding4051Magnesium By similarity
Metal binding4091Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Z8E5 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 638B8A8BA985A458

FASTA56960,397
        10         20         30         40         50         60 
MSRKQLALFE PVLLVQALTD AVKKLSPRAQ WRNPVMFVVW AGSVLATLLT LAMVTGQIAG 

        70         80         90        100        110        120 
SALFTGVISL WLWFTVLFAN FAEALAEGRS KAQANSLKGV KKTAFARRLR APRHDAQADN 

       130        140        150        160        170        180 
VPAAELRKGD IVLVKAGDII PCDGEVIEGG ASVDESAITG ESAPVIRESG GDFASVTGGR 

       190        200        210        220        230        240 
AVEAAGDVDV LLLDKTGTIT LGNRQASDFI PARGVDERTL ADAAQLASLA DETPEGRSIV 

       250        260        270        280        290        300 
ILAKQRFNLR ERDVQSLHAT FVPFTAQSRM SGINIDNRMI RKGSVDAIRR HVESNGGHFP 

       310        320        330        340        350        360 
ADVEQNVENV ARLGATPLVV VEGARVLGVI ALKDIVKGGI KERFAQLRKM GIKTVMITGD 

       370        380        390        400        410        420 
NRLTAAAIAA EAGVDDFLAE ATPEAKLALI RQYQAEGRLV AMTGDGTNDA PALAQADVAV 

       430        440        450        460        470        480 
AMNSGTQAAK EAGNMVDLDS NPTKLIEVVH IGKQMLMTRG SLTTFSIAND VAKYFAIIPA 

       490        500        510        520        530        540 
AFAATYPQLN ALNVMGLHSP NSAILSAVIF NALIIIFLIP LALKGVSYKP LSASAMLRRN 

       550        560 
LWIYGLGGLV VPFIGIKVID VLLTLLDLA

« Hide

References

[1]"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18."
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. expand/collapse author list , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.
Nature 413:848-852(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CT18.
[2]"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700931 / Ty2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL627267 Genomic DNA. Translation: CAD05168.1.
AE014613 Genomic DNA. Translation: AAO69781.1.
RefSeqNP_805921.1. NC_004631.1.

3D structure databases

ProteinModelPortalQ8Z8E5.
SMRQ8Z8E5. Positions 203-338.
ModBaseSearch...

Protein-protein interaction databases

STRING220341.STY0746.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO69781; AAO69781; t2170.
CAD05168; CAD05168; CAD05168.
GeneID1067286.
KEGGstt:t2170.
PATRIC18539355. VBISalEnt120419_0752.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2216.
HOGENOMHOG000244113.
KOK01547.
OMAMHLATPA.
ProtClustDBCLSK275805.

Family and domain databases

Gene3D2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
HAMAPMF_00285. KdpB. Divergent sequence.
InterProIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
IPR006391. K-transp_ATPase_bsu_IA.
[Graphical view]
PANTHERPTHR24093. PTHR24093. 1 hit.
PfamPF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01494. ATPase_P-type. 1 hit.
TIGR01497. kdpB. 1 hit.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATKB_SALTI
AccessionPrimary (citable) accession number: Q8Z8E5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: March 1, 2002
Last modified: May 1, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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