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Q8Z8A2

- 6PGL_SALTI

UniProt

Q8Z8A2 - 6PGL_SALTI

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Protein

6-phosphogluconolactonase

Gene
pgl, STY0818, t2102
Organism
Salmonella typhi
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6-P-gluconolactonase
Gene namesi
Name:pgl
Ordered Locus Names:STY0818, t2102
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000541: Chromosome, UP000002670: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3313316-phosphogluconolactonaseUniRule annotationPRO_0000171138Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220341.STY0818.

Structurei

3D structure databases

ProteinModelPortaliQ8Z8A2.
SMRiQ8Z8A2. Positions 1-331.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiDKRFLYV.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8Z8A2-1 [UniParc]FASTAAdd to Basket

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MKQTVYTASP ESQQIHVWSL NHEGTLTLVQ VVDVPGQVQP MVVSPDKRYL    50
YVGVRPEFRV LAYRIAPDDG ALTFAAESAL PGSPTHISTD HHGRFVFVGS 100
YNAGNVSVTR LQDGLPVELV DVVEGLDGCH SANITPDNRT LWVPALKQDR 150
ICLFTLSDDG HLVAQEPAEV NTVEGAGPRH MVFHPNRQYA YCVNELNSSV 200
DVWQLKNPHG EIECVQTLDM MPADFSDTRW AADIHITPDG RHLYACDRTA 250
SLITVFSVSE DGSVLSVEGF QPTEAQPRGF NIDNSRKYLI AAGQKSHHIA 300
VYEITGTQGL LTEKGRYAVG QGPMWVVVNA Y 331
Length:331
Mass (Da):36,436
Last modified:March 1, 2002 - v1
Checksum:i3EBB46DF97112DD5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL513382 Genomic DNA. Translation: CAD05233.1.
AE014613 Genomic DNA. Translation: AAO69719.1.
RefSeqiNP_455327.1. NC_003198.1.
NP_805859.1. NC_004631.1.

Genome annotation databases

EnsemblBacteriaiAAO69719; AAO69719; t2102.
CAD05233; CAD05233; CAD05233.
GeneIDi1247265.
KEGGisty:STY0818.
PATRICi18539501. VBISalEnt120419_0822.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL513382 Genomic DNA. Translation: CAD05233.1 .
AE014613 Genomic DNA. Translation: AAO69719.1 .
RefSeqi NP_455327.1. NC_003198.1.
NP_805859.1. NC_004631.1.

3D structure databases

ProteinModelPortali Q8Z8A2.
SMRi Q8Z8A2. Positions 1-331.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220341.STY0818.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO69719 ; AAO69719 ; t2102 .
CAD05233 ; CAD05233 ; CAD05233 .
GeneIDi 1247265.
KEGGi sty:STY0818.
PATRICi 18539501. VBISalEnt120419_0822.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi DKRFLYV.
OrthoDBi EOG615VK7.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
SUPFAMi SSF50974. SSF50974. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2.

Entry informationi

Entry namei6PGL_SALTI
AccessioniPrimary (citable) accession number: Q8Z8A2
Secondary accession number(s): Q7C8Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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