Q8Z7J5 (Q8Z7J5_SALTI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malonyl CoA-acyl carrier protein transacylase PIRNR PIRNR000446
EC=2.3.1.39 PIRNR PIRNR000446

Gene names

Name:	fabD EMBL AAO69350.1
Ordered Locus Names:	STY1233 EMBL CAD08318.1, t1726 EMBL AAO69350.1

Organism

Salmonella typhi [Complete proteome] [HAMAP] EMBL CAD08318.1

Taxonomic identifier

90370 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-protein]. PIRNR PIRNR000446
Sequence similarities	Belongs to the fabD family. PIRNR PIRNR000446

Ontologies

Keywords
Molecular function	Acyltransferase PIRNR PIRNR000446 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	[acyl-carrier-protein] S-malonyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8Z7J5 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 83B4AB7FE13C8CB3	FASTA	309	32,435
	10 20 30 40 50 60 MTQFAFVFPG QGSQSVGMLA EMAANYPIVE ETFAEASAAL GYDLWALTQQ GPAEELNKTW 70 80 90 100 110 120 QTQPALLTAS VALWRVWQQQ GGKMPALMAG HSLGEYSALV CAGVINFADA VRLVEMRGKF 130 140 150 160 170 180 MQEAVPEGTG GMSAIIGLDD ASIAKACEES AEGQVVSPVN FNSPGQVVIA GHKEAVERAG 190 200 210 220 230 240 AACKAAGAKR ALPLPVSVPS HCALMKPTAD KLAVELAKIT FSAPTVPVVN NVDVKCETDA 250 260 270 280 290 300 AAIRDALVRQ LYNPVQWTKS VEFIAAQGVE HLYEVGPGKV LTGLTKRIVD TLTASALNEP AALSAALTQ

References

[1]

"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18." Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:848-852(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CT18 EMBL CAD08318.1.

[2]

"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18." Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700931 / Ty2 and Ty2 EMBL AAO69350.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014613 Genomic DNA. Translation: AAO69350.1. AL627269 Genomic DNA. Translation: CAD08318.1.
RefSeq	NP_805501.1. NC_004631.1.
3D structure databases
HSSP	HSSP built from PDB template 1MLA based on UniProtKB P25715.
SMR	Q8Z7J5. Positions 3-307.
ModBase	Search...
Protein-protein interaction databases
STRING	220341.STY1233.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO69350; AAO69350; t1726. CAD08318; CAD08318; CAD08318.
GeneID	1071365.
KEGG	stt:t1726.
PATRIC	18540339. VBISalEnt120419_1235.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000036503.
KO	K00645.
OMA	EVSGPFH.
ProtClustDB	CLSK2459431.
Family and domain databases
Gene3D	3.40.366.10. 2 hits.
InterPro	IPR001227. Ac_transferase_dom. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR024925. Malonyl_CoA-ACP_transAc. IPR004410. Malonyl_CoA-ACP_transAc_FabD. IPR016036. Malonyl_transacylase_ACP-bd. [Graphical view]
Pfam	PF00698. Acyl_transf_1. 1 hit. [Graphical view]
PIRSF	PIRSF000446. Mct. 1 hit.
SUPFAM	SSF52151. Acyl_Trfase/lysoPlipase. 1 hit. SSF55048. Malonyl_transacylase_ACP-bd. 1 hit.
TIGRFAMs	TIGR00128. fabD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8Z7J5_SALTI

Accession

Primary (citable) accession number: Q8Z7J5
Secondary accession number(s): Q7C9C5

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)