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Protein

Superoxide dismutase [Cu-Zn]

Gene

sodCII

Organism
Salmonella typhi
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodCIIImported
Synonyms:sodCImported
Ordered Locus Names:STY1682Imported, t1308Imported
ORF Names:ACT03_02105Imported, ACT04_13580Imported, ERS083263_03100Imported, ERS325172_02367Imported, ERS325188_02353Imported, ERS325190_02699Imported, ERS325196_02020Imported, ERS325215_03113Imported, ERS325223_02354Imported, ERS325225_02895Imported, ERS325232_02356Imported, ERS325296_02377Imported, ERS325302_02972Imported, ERS325320_02131Imported, ERS325374_02538Imported, ERS325389_02356Imported, ERS325400_03205Imported, ERS325434_02738Imported, ERS325436_02350Imported, ERS325437_02451Imported, ERS325458_02947Imported, ERS326267_02213Imported, ERS326389_02429Imported, ERS326420_02428Imported, ERS326462_02590Imported, ERS326499_02401Imported, ERS327392_03146Imported
OrganismiSalmonella typhiImported
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000002670 Componenti: Chromosome UP000000541 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 173154Superoxide dismutase [Cu-Zn]Sequence analysisPRO_5005942057Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220341.STY1682.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 172140Sod_CuInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiCOG2032. LUCA.
ENOG4108Z7T. Bacteria.
HOGENOMiHOG000263449.
KOiK04565.
OMAiGARYACG.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERiPTHR10003. PTHR10003. 1 hit.
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Z6P6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLSLAMVT LLACAGAQAA SEKVEMNLVT AQGVGQSIGT VVIDETEGGL
60 70 80 90 100
KFTPHLKALP PGEHGFHIHA KGSCQPAIKD GKAVAAEAAG GHLDPQNTGK
110 120 130 140 150
HEGPEGQGHL GDLPVLVVNN DGIATEPVTA PRLKSLDEVK DKALMIHVGG
160 170
DNMSDQPKPL GGGGTRYACG VIK
Length:173
Mass (Da):17,735
Last modified:March 1, 2002 - v1
Checksum:i00A5A8B6AF25B4EF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei173 – 1731Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014613 Genomic DNA. Translation: AAO68958.1.
EU181430 Genomic DNA. Translation: ABW24660.1.
CP012091 Genomic DNA. Translation: ALG16106.1.
CP012151 Genomic DNA. Translation: ALG22560.1.
AL513382 Genomic DNA. Translation: CAD01927.1.
CEXJ01000009 Genomic DNA. Translation: CER23372.1.
CEXP01000010 Genomic DNA. Translation: CER52142.1.
CEXU01000014 Genomic DNA. Translation: CER74456.1.
CEYF01000010 Genomic DNA. Translation: CES21303.1.
CEYH01000009 Genomic DNA. Translation: CES34466.1.
CEYU01000010 Genomic DNA. Translation: CES91408.1.
CEZA01000015 Genomic DNA. Translation: CET27819.1.
CUYV01000008 Genomic DNA. Translation: CQS90269.1.
CUZW01000008 Genomic DNA. Translation: CQS93847.1.
CUZH01000009 Genomic DNA. Translation: CQS97252.1.
CUYW01000009 Genomic DNA. Translation: CQT01800.1.
CUZV01000009 Genomic DNA. Translation: CQT03509.1.
CUYZ01000010 Genomic DNA. Translation: CQT12127.1.
CUYJ01000013 Genomic DNA. Translation: CQT24160.1.
CUZM01000014 Genomic DNA. Translation: CQT26357.1.
CUYQ01000014 Genomic DNA. Translation: CQT27889.1.
CUYO01000015 Genomic DNA. Translation: CQT44329.1.
CVAI01000009 Genomic DNA. Translation: CQV05397.1.
CVBK01000009 Genomic DNA. Translation: CQV37004.1.
CVCK01000009 Genomic DNA. Translation: CQX11596.1.
CVCL01000010 Genomic DNA. Translation: CQX17464.1.
CVCJ01000012 Genomic DNA. Translation: CQX27679.1.
CVCV01000010 Genomic DNA. Translation: CQX74986.1.
CVFY01000014 Genomic DNA. Translation: CRB54259.1.
CVGS01000009 Genomic DNA. Translation: CRC67296.1.
RefSeqiNP_456090.1. NC_003198.1.
WP_000826818.1. NZ_CXZB01000010.1.

Genome annotation databases

EnsemblBacteriaiCAD01927; CAD01927; CAD01927.
CEP53172; CEP53172; ERS325052_02286.
CEQ68488; CEQ68488; ERS326331_02586.
CER15015; CER15015; ERS248971_03186.
CER19051; CER19051; ERS326259_02559.
CER23372; CER23372; ERS325172_02367.
CER28847; CER28847; ERS326407_02312.
CER46621; CER46621; ERS326268_02559.
CER52142; CER52142; ERS326420_02428.
CER55946; CER55946; ERS325165_02773.
CER63800; CER63800; ERS325101_02347.
CER65465; CER65465; ERS326373_02600.
CER67317; CER67317; ERS326475_03168.
CES06492; CES06492; ERS326249_02224.
CES13376; CES13376; ERS326256_02564.
CES21303; CES21303; ERS326389_02429.
CES34466; CES34466; ERS326267_02213.
CES91408; CES91408; ERS326462_02590.
CET06321; CET06321; ERS326456_02358.
CET27819; CET27819; ERS083263_03100.
CET28965; CET28965; ERS326469_02334.
CET80531; CET80531; ERS326314_02562.
CET85170; CET85170; ERS326412_02233.
CET96640; CET96640; ERS326275_02557.
CEU14117; CEU14117; ERS326422_02540.
GeneIDi1248056.
KEGGistt:t1308.
sty:STY1682.
PATRICi18541256. VBISalEnt120419_1692.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014613 Genomic DNA. Translation: AAO68958.1.
EU181430 Genomic DNA. Translation: ABW24660.1.
CP012091 Genomic DNA. Translation: ALG16106.1.
CP012151 Genomic DNA. Translation: ALG22560.1.
AL513382 Genomic DNA. Translation: CAD01927.1.
CEXJ01000009 Genomic DNA. Translation: CER23372.1.
CEXP01000010 Genomic DNA. Translation: CER52142.1.
CEXU01000014 Genomic DNA. Translation: CER74456.1.
CEYF01000010 Genomic DNA. Translation: CES21303.1.
CEYH01000009 Genomic DNA. Translation: CES34466.1.
CEYU01000010 Genomic DNA. Translation: CES91408.1.
CEZA01000015 Genomic DNA. Translation: CET27819.1.
CUYV01000008 Genomic DNA. Translation: CQS90269.1.
CUZW01000008 Genomic DNA. Translation: CQS93847.1.
CUZH01000009 Genomic DNA. Translation: CQS97252.1.
CUYW01000009 Genomic DNA. Translation: CQT01800.1.
CUZV01000009 Genomic DNA. Translation: CQT03509.1.
CUYZ01000010 Genomic DNA. Translation: CQT12127.1.
CUYJ01000013 Genomic DNA. Translation: CQT24160.1.
CUZM01000014 Genomic DNA. Translation: CQT26357.1.
CUYQ01000014 Genomic DNA. Translation: CQT27889.1.
CUYO01000015 Genomic DNA. Translation: CQT44329.1.
CVAI01000009 Genomic DNA. Translation: CQV05397.1.
CVBK01000009 Genomic DNA. Translation: CQV37004.1.
CVCK01000009 Genomic DNA. Translation: CQX11596.1.
CVCL01000010 Genomic DNA. Translation: CQX17464.1.
CVCJ01000012 Genomic DNA. Translation: CQX27679.1.
CVCV01000010 Genomic DNA. Translation: CQX74986.1.
CVFY01000014 Genomic DNA. Translation: CRB54259.1.
CVGS01000009 Genomic DNA. Translation: CRC67296.1.
RefSeqiNP_456090.1. NC_003198.1.
WP_000826818.1. NZ_CXZB01000010.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220341.STY1682.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD01927; CAD01927; CAD01927.
CEP53172; CEP53172; ERS325052_02286.
CEQ68488; CEQ68488; ERS326331_02586.
CER15015; CER15015; ERS248971_03186.
CER19051; CER19051; ERS326259_02559.
CER23372; CER23372; ERS325172_02367.
CER28847; CER28847; ERS326407_02312.
CER46621; CER46621; ERS326268_02559.
CER52142; CER52142; ERS326420_02428.
CER55946; CER55946; ERS325165_02773.
CER63800; CER63800; ERS325101_02347.
CER65465; CER65465; ERS326373_02600.
CER67317; CER67317; ERS326475_03168.
CES06492; CES06492; ERS326249_02224.
CES13376; CES13376; ERS326256_02564.
CES21303; CES21303; ERS326389_02429.
CES34466; CES34466; ERS326267_02213.
CES91408; CES91408; ERS326462_02590.
CET06321; CET06321; ERS326456_02358.
CET27819; CET27819; ERS083263_03100.
CET28965; CET28965; ERS326469_02334.
CET80531; CET80531; ERS326314_02562.
CET85170; CET85170; ERS326412_02233.
CET96640; CET96640; ERS326275_02557.
CEU14117; CEU14117; ERS326422_02540.
GeneIDi1248056.
KEGGistt:t1308.
sty:STY1682.
PATRICi18541256. VBISalEnt120419_1692.

Phylogenomic databases

eggNOGiCOG2032. LUCA.
ENOG4108Z7T. Bacteria.
HOGENOMiHOG000263449.
KOiK04565.
OMAiGARYACG.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERiPTHR10003. PTHR10003. 1 hit.
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18Imported.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2Imported and Ty2Imported.
  3. "Cloning and sequencing of sodC gene from Salmonella typhi."
    Kasetty S.M., Shivannavar C.T.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Informatics Pathogen
    Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A59307Imported, Dn136Imported, Dn160Imported, Dn189Imported, Dn45Imported, Dtc103Imported, Dtc81Imported, Dtc98Imported, IB5341Imported, Ipt57Imported, MDUST167Imported, MDUST289Imported, MDUST320Imported, MDUST362Imported, MDUST399Imported, Np93Imported, Ty1-16Imported, Ty2-101Imported, Ty2-107Imported, Ty2-115Imported, Ty2-120Imported, Ty2-170Imported, Ty2-71Imported, Ty2-75Imported and Ty3-193Imported.
  5. "Complete Genome Sequence of Salmonella enterica sibsp. enterica serovar Typhi Isolate B/SF/13/03/195 Associated with a Typhoid Carrier in Pasir Mas, Kelantan, Malaysia."
    Muhamad Harish S., Sim K.S., Mohd Nor F., Mat Hussin H., Hamzah W.M., Mohd Najimuddin M.N., Ismail A.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: B/SF/13/03/195Imported.
  6. "Genome Sequence of Salmonella enterica subsp. enterica serovar Typhi Isolate PM016/13 from Well Water Associated with a Typhoid Outbreak in Pasir Mas, Kelantan, Malaysia."
    Ismail A., Muhamad Harish S., Sim K.S., Mohd Najimuddin M.N.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PM016/13Imported.

Entry informationi

Entry nameiQ8Z6P6_SALTI
AccessioniPrimary (citable) accession number: Q8Z6P6
Secondary accession number(s): A0A0C9E9R1, A0A0C9FYP8, Q7CA25
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: January 20, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.