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Q8Z5G5

- WZB_SALTI

UniProt

Q8Z5G5 - WZB_SALTI

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Protein
Low molecular weight protein-tyrosine-phosphatase wzb
Gene
wzb, STY2330, t0755
Organism
Salmonella typhi
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Dephosphorylates wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91Nucleophile By similarity
Active sitei14 – 141 By similarity
Active sitei115 – 1151Proton donor By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. polysaccharide biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Exopolysaccharide synthesis

Enzyme and pathway databases

UniPathwayiUPA00631.

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase wzb (EC:3.1.3.48)
Gene namesi
Name:wzb
Ordered Locus Names:STY2330, t0755
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000541: Chromosome, UP000002670: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 149149Low molecular weight protein-tyrosine-phosphatase wzb
PRO_0000046574Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220341.STY2330.

Structurei

3D structure databases

ProteinModelPortaliQ8Z5G5.
SMRiQ8Z5G5. Positions 1-146.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0394.
HOGENOMiHOG000273091.
KOiK01104.
OMAiCELAPEM.
OrthoDBiEOG63VC26.

Family and domain databases

InterProiIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717. PTHR11717. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8Z5G5-1 [UniParc]FASTAAdd to Basket

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MFNKILVVCV GNVCRSPTAE RLLKRFHPSL TVASAGLGAL VGKGADPAAA    50
SVASAHDLSL ENHCARQISA RLCREYDLIL TMEKRHIAAL CDIAPEMRSK 100
VMLFGHWDSE REIPDPYRKS RDAFEAVYTL LERSARQWAQ ALNAEQGKP 149
Length:149
Mass (Da):16,504
Last modified:March 1, 2002 - v1
Checksum:iDA5DE2C3B2E83208
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL513382 Genomic DNA. Translation: CAD02480.1.
AE014613 Genomic DNA. Translation: AAO68448.1.
RefSeqiNP_456663.1. NC_003198.1.
NP_804599.1. NC_004631.1.

Genome annotation databases

EnsemblBacteriaiAAO68448; AAO68448; t0755.
CAD02480; CAD02480; CAD02480.
GeneIDi1248662.
KEGGisty:STY2330.
PATRICi18542603. VBISalEnt120419_2351.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL513382 Genomic DNA. Translation: CAD02480.1 .
AE014613 Genomic DNA. Translation: AAO68448.1 .
RefSeqi NP_456663.1. NC_003198.1.
NP_804599.1. NC_004631.1.

3D structure databases

ProteinModelPortali Q8Z5G5.
SMRi Q8Z5G5. Positions 1-146.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220341.STY2330.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO68448 ; AAO68448 ; t0755 .
CAD02480 ; CAD02480 ; CAD02480 .
GeneIDi 1248662.
KEGGi sty:STY2330.
PATRICi 18542603. VBISalEnt120419_2351.

Phylogenomic databases

eggNOGi COG0394.
HOGENOMi HOG000273091.
KOi K01104.
OMAi CELAPEM.
OrthoDBi EOG63VC26.

Enzyme and pathway databases

UniPathwayi UPA00631 .

Family and domain databases

InterProi IPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view ]
PANTHERi PTHR11717. PTHR11717. 1 hit.
Pfami PF01451. LMWPc. 1 hit.
[Graphical view ]
PRINTSi PR00719. LMWPTPASE.
SMARTi SM00226. LMWPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52788. SSF52788. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2.

Entry informationi

Entry nameiWZB_SALTI
AccessioniPrimary (citable) accession number: Q8Z5G5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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