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Q8Z5G5

- WZB_SALTI

UniProt

Q8Z5G5 - WZB_SALTI

Protein

Low molecular weight protein-tyrosine-phosphatase wzb

Gene

wzb

Organism
Salmonella typhi
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    • Comment

    Functioni

    Dephosphorylates wzc. Required for the extracellular polysaccharide colanic acid synthesis. Probably involved in the export of colanic acid from the cell to medium By similarity.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei9 – 91NucleophileBy similarity
    Active sitei14 – 141By similarity
    Active sitei115 – 1151Proton donorBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. polysaccharide biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Exopolysaccharide synthesis

    Enzyme and pathway databases

    UniPathwayiUPA00631.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Low molecular weight protein-tyrosine-phosphatase wzb (EC:3.1.3.48)
    Gene namesi
    Name:wzb
    Ordered Locus Names:STY2330, t0755
    OrganismiSalmonella typhi
    Taxonomic identifieri90370 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000000541: Chromosome, UP000002670: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 149149Low molecular weight protein-tyrosine-phosphatase wzbPRO_0000046574Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi220341.STY2330.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8Z5G5.
    SMRiQ8Z5G5. Positions 1-146.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0394.
    HOGENOMiHOG000273091.
    KOiK01104.
    OMAiCELAPEM.
    OrthoDBiEOG63VC26.

    Family and domain databases

    InterProiIPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view]
    PANTHERiPTHR11717. PTHR11717. 1 hit.
    PfamiPF01451. LMWPc. 1 hit.
    [Graphical view]
    PRINTSiPR00719. LMWPTPASE.
    SMARTiSM00226. LMWPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52788. SSF52788. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8Z5G5-1 [UniParc]FASTAAdd to Basket

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    MFNKILVVCV GNVCRSPTAE RLLKRFHPSL TVASAGLGAL VGKGADPAAA    50
    SVASAHDLSL ENHCARQISA RLCREYDLIL TMEKRHIAAL CDIAPEMRSK 100
    VMLFGHWDSE REIPDPYRKS RDAFEAVYTL LERSARQWAQ ALNAEQGKP 149
    Length:149
    Mass (Da):16,504
    Last modified:March 1, 2002 - v1
    Checksum:iDA5DE2C3B2E83208
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL513382 Genomic DNA. Translation: CAD02480.1.
    AE014613 Genomic DNA. Translation: AAO68448.1.
    RefSeqiNP_456663.1. NC_003198.1.
    NP_804599.1. NC_004631.1.

    Genome annotation databases

    EnsemblBacteriaiAAO68448; AAO68448; t0755.
    CAD02480; CAD02480; CAD02480.
    GeneIDi1248662.
    KEGGisty:STY2330.
    PATRICi18542603. VBISalEnt120419_2351.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL513382 Genomic DNA. Translation: CAD02480.1 .
    AE014613 Genomic DNA. Translation: AAO68448.1 .
    RefSeqi NP_456663.1. NC_003198.1.
    NP_804599.1. NC_004631.1.

    3D structure databases

    ProteinModelPortali Q8Z5G5.
    SMRi Q8Z5G5. Positions 1-146.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 220341.STY2330.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO68448 ; AAO68448 ; t0755 .
    CAD02480 ; CAD02480 ; CAD02480 .
    GeneIDi 1248662.
    KEGGi sty:STY2330.
    PATRICi 18542603. VBISalEnt120419_2351.

    Phylogenomic databases

    eggNOGi COG0394.
    HOGENOMi HOG000273091.
    KOi K01104.
    OMAi CELAPEM.
    OrthoDBi EOG63VC26.

    Enzyme and pathway databases

    UniPathwayi UPA00631 .

    Family and domain databases

    InterProi IPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view ]
    PANTHERi PTHR11717. PTHR11717. 1 hit.
    Pfami PF01451. LMWPc. 1 hit.
    [Graphical view ]
    PRINTSi PR00719. LMWPTPASE.
    SMARTi SM00226. LMWPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52788. SSF52788. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CT18.
    2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
      Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
      J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700931 / Ty2.

    Entry informationi

    Entry nameiWZB_SALTI
    AccessioniPrimary (citable) accession number: Q8Z5G5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 3, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3