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Protein

Transcriptional regulatory protein YehT

Gene

yehT

Organism
Salmonella typhi
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system YehU/YehT, which may be involved in the stationary-phase control network. Regulates expression of yjiY by binding to its promoter region (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein YehT
Gene namesi
Name:yehT
Ordered Locus Names:STY2388, t0697
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 239239Transcriptional regulatory protein YehTPRO_0000081364Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei54 – 5414-aspartylphosphatePROSITE-ProRule annotation

Post-translational modificationi

Phosphorylated by YehU.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi220341.STY2388.

Structurei

3D structure databases

ProteinModelPortaliQ8Z5C1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 116114Response regulatoryPROSITE-ProRule annotationAdd
BLAST
Domaini137 – 239103HTH LytTR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH LytTR-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108NEV. Bacteria.
COG3279. LUCA.
HOGENOMiHOG000242207.
KOiK02477.
OMAiHDAFALR.
OrthoDBiEOG64R63J.

Family and domain databases

InterProiIPR011006. CheY-like_superfamily.
IPR007492. LytTR_DNA-bd_dom.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF04397. LytTR. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00850. LytTR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50930. HTH_LYTTR. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Z5C1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKVLIVDDE PLARENLRIL LQGQDDIEIV GECANAVEAI GAVHKLRPDV
60 70 80 90 100
LFLDIQMPRI SGLEIVGMLD PEHRPYIVFL TAFDEYAIKA FEEHAFDYLL
110 120 130 140 150
KPIEEKRLEK TLHRLRQERS KQDVSLLPEN QQALKFIPCT GHSRIYLLQM
160 170 180 190 200
DDVAFVSSRM SGVYVTSSEG KEGFTELTLR TLESRTPLLR CHRQFLVNMA
210 220 230
HLQEIRLEDN GQAELILRNG LTVPVSRRYL KSLKEAIGL
Length:239
Mass (Da):27,392
Last modified:March 1, 2002 - v1
Checksum:iF35AA90C75F5225C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti131 – 1311Q → S in AAO68394 (PubMed:12644504).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD02538.1.
AE014613 Genomic DNA. Translation: AAO68394.1.
RefSeqiNP_456718.1. NC_003198.1.
WP_000598632.1. NZ_FFOG01000001.1.
WP_000598634.1. NZ_CVPP01000001.1.

Genome annotation databases

EnsemblBacteriaiAAO68394; AAO68394; t0697.
CAD02538; CAD02538; CAD02538.
GeneIDi1248720.
KEGGistt:t0697.
sty:STY2388.
PATRICi18542723. VBISalEnt120419_2412.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD02538.1.
AE014613 Genomic DNA. Translation: AAO68394.1.
RefSeqiNP_456718.1. NC_003198.1.
WP_000598632.1. NZ_FFOG01000001.1.
WP_000598634.1. NZ_CVPP01000001.1.

3D structure databases

ProteinModelPortaliQ8Z5C1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220341.STY2388.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO68394; AAO68394; t0697.
CAD02538; CAD02538; CAD02538.
GeneIDi1248720.
KEGGistt:t0697.
sty:STY2388.
PATRICi18542723. VBISalEnt120419_2412.

Phylogenomic databases

eggNOGiENOG4108NEV. Bacteria.
COG3279. LUCA.
HOGENOMiHOG000242207.
KOiK02477.
OMAiHDAFALR.
OrthoDBiEOG64R63J.

Family and domain databases

InterProiIPR011006. CheY-like_superfamily.
IPR007492. LytTR_DNA-bd_dom.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF04397. LytTR. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00850. LytTR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50930. HTH_LYTTR. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2.

Entry informationi

Entry nameiYEHT_SALTI
AccessioniPrimary (citable) accession number: Q8Z5C1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: March 1, 2002
Last modified: May 11, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.