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Reviewed, UniProtKB/Swiss-Prot Q8Z460 (CYSH_SALTI)

Last modified February 9, 2010. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Phosphoadenosine phosphosulfate reductase
    EC=1.8.4.8
Alternative name(s):
    PAPS reductase, thioredoxin dependent
    PAdoPS reductase
    3'-phosphoadenylylsulfate reductase
    PAPS sulfotransferase
Gene names
Name: cysH
Ordered Locus Names: STY3074, t2847
OrganismSalmonella typhi [Complete proteome] [HAMAP]
Taxonomic identifier90370 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite. HAMAP MF_00063

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063

Subunit structure

Homodimer By similarity. HAMAP MF_00063

Subcellular location

Cytoplasm By similarity HAMAP MF_00063.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 244243Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
PRO_0000100642

Sequences

Sequence LengthMass (Da)Tools
Q8Z460-1 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 8B08DCF029CE141D

FASTA24427,938
        10         20         30         40         50         60 
MSQLDLNALN ELPKVDRVLA LAETNAQLET LTAEERVAWA LENLPGEYVL SSSFGIQAAV 

        70         80         90        100        110        120 
SLHLVNQIRP DIPVILTDTG YLFPETYQFI DELTDKLKLN LKVYRAGESP AWQEARYGKL 

       130        140        150        160        170        180 
WEQGVEGIEK YNEINKVEPM NRALKELNAQ TWFAGLRREQ SGSRAHLPVL AIQRGVFKVL 

       190        200        210        220        230        240 
PIIDWDNRTV YQYLQKHGLK YHPLWAQGYL SVGDTHTTRK WEPGMAEEET RFFGLKRECG 


LHEG 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL627276 Genomic DNA. Translation: CAD06052.1.
AE014613 Genomic DNA. Translation: AAO70404.1.
RefSeqNP_457335.1.
NP_806544.1.

3D structure databases

SMRQ8Z460. Positions 2-244.
ModBaseSearch...

Genome annotation databases

GeneID1068742.
1249374.
GenomeReviewsGene locus t2847 in contig AE014613_GR.
KEGGstt:t2847.
sty:STY3074.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG758022.
OMAAIHGTRF.

Enzyme and pathway databases

BioCycSENT209261:T2847-MONOMER.
SENT220341:STY3074-MONOMER.
BRENDA1.8.4.8. 3716.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR004511. PAdo_PSO4_Rdtase_CysH.
IPR002500. PAPS_reduct.
IPR011800. PAPS_reductase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
TIGRFAMsTIGR00434. cysH. 1 hit.
TIGR02057. PAPS_reductase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSH_SALTI
AccessionPrimary (citable) accession number: Q8Z460
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: January 23, 2007
Last modified: February 9, 2010
This is version 56 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents