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Protein

L-fuculokinase

Gene

fucK

Organism
Salmonella typhi
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of L-fuculose.UniRule annotation

Catalytic activityi

ATP + L-fuculose = ADP + L-fuculose 1-phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Pathwayi: L-fucose degradation

This protein is involved in step 2 of the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. L-fucose isomerase (fucI)
  2. L-fuculokinase (fucK)
  3. L-fuculose phosphate aldolase (fucA)
This subpathway is part of the pathway L-fucose degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose, the pathway L-fucose degradation and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism, Fucose metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00563; UER00625

Names & Taxonomyi

Protein namesi
Recommended name:
L-fuculokinaseUniRule annotation (EC:2.7.1.51UniRule annotation)
Alternative name(s):
L-fuculose kinaseUniRule annotation
Gene namesi
Name:fucKUniRule annotation
Ordered Locus Names:STY3117, t2885
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000594261 – 472L-fuculokinaseAdd BLAST472

Interactioni

Protein-protein interaction databases

STRINGi220341.STY3117

Structurei

3D structure databases

ProteinModelPortaliQ8Z428
SMRiQ8Z428
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMG Bacteria
COG1070 LUCA
HOGENOMiHOG000124178
KOiK00879
OMAiKKGRIFC

Family and domain databases

HAMAPiMF_00986 Fuculokinase, 1 hit
InterProiView protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018483 Carb_kinase_FGGY_CS
IPR018484 Carb_kinase_FGGY_N
IPR013450 Fuculokinase
PANTHERiPTHR10196:SF60 PTHR10196:SF60, 1 hit
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
PIRSFiPIRSF000538 GlpK, 1 hit
TIGRFAMsiTIGR02628 fuculo_kin_coli, 1 hit
PROSITEiView protein in PROSITE
PS00933 FGGY_KINASES_1, 1 hit
PS00445 FGGY_KINASES_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8Z428-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQDVILVLD CGATNVRAIA VDRQGKIVAR ASTANASDIA AENSAWHQWS
60 70 80 90 100
LDAILQRFAD CCRSLSSALS ECVVRGITVT TFGVDGALVD AQGKLLYPVI
110 120 130 140 150
SWKCPRTAAV METIERFISP RQLQTLSGVG AFSFNTLYKL VWLKENHPRL
160 170 180 190 200
LEQAHCWLFI SSLINHRLTG EFTTDITMAG TSQLLDIHQR DFSPEILQAT
210 220 230 240 250
GLARRLFPRI VEAGAPIGTL QTDAARLLGL PAGVPVISAE HDTQFALFGA
260 270 280 290 300
GAQQGEPVLS SGTWEILMVR SGQVDTSLLS QYPGSTCELD SQSGLYNPGM
310 320 330 340 350
QWLASGVLEW VRKLLWTPET PWQTLIDEAR AIPAGAEGVR MQCDLLACQN
360 370 380 390 400
AGWQGVTLNT TRGHFYRAAL EGLTAQLQRN LRTLEKIGHF NATELLLVGG
410 420 430 440 450
GSRNALWNQI KANQLDIPIK VLDDAETTVA GAAMFGWYGV GEFSSPEQAR
460 470
AQVNYQYRYF WPQTEPEIIE GV
Length:472
Mass (Da):51,746
Last modified:March 1, 2002 - v1
Checksum:i5CD73548EED519E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD02803.1
AE014613 Genomic DNA Translation: AAO70441.1
RefSeqiNP_457372.1, NC_003198.1
WP_001763972.1, NZ_PHKG01000005.1

Genome annotation databases

EnsemblBacteriaiAAO70441; AAO70441; t2885
CAD02803; CAD02803; CAD02803
GeneIDi1249413
KEGGistt:t2885
sty:STY3117
PATRICifig|220341.7.peg.3172

Similar proteinsi

Entry informationi

Entry nameiFUCK_SALTI
AccessioniPrimary (citable) accession number: Q8Z428
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health