Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

L-fuculokinase

Gene

fucK

Organism
Salmonella typhi
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of L-fuculose.UniRule annotation

Catalytic activityi

ATP + L-fuculose = ADP + L-fuculose 1-phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotation

Pathway: L-fucose degradation

This protein is involved in step 2 of the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. L-fucose isomerase (fucI), L-fucose isomerase (fucI), L-fucose isomerase (fucI)
  2. L-fuculokinase (fucK), L-fuculokinase (fucK)
  3. L-fuculose phosphate aldolase (fucA_1), L-fuculose phosphate aldolase (fucA_1)
This subpathway is part of the pathway L-fucose degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-lactaldehyde and glycerone phosphate from L-fucose, the pathway L-fucose degradation and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Fucose metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00563; UER00625.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fuculokinaseUniRule annotation (EC:2.7.1.51UniRule annotation)
Alternative name(s):
L-fuculose kinaseUniRule annotation
Gene namesi
Name:fucKUniRule annotation
Ordered Locus Names:STY3117, t2885
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000541 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 472472L-fuculokinasePRO_0000059426Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220341.STY3117.

Structurei

3D structure databases

ProteinModelPortaliQ8Z428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1070.
HOGENOMiHOG000124178.
KOiK00879.
OMAiATNVRAM.
OrthoDBiEOG6X9MHN.

Family and domain databases

HAMAPiMF_00986. Fuculokinase.
InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR013450. Fuculokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
TIGRFAMsiTIGR02628. fuculo_kin_coli. 1 hit.
PROSITEiPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Z428-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQDVILVLD CGATNVRAIA VDRQGKIVAR ASTANASDIA AENSAWHQWS
60 70 80 90 100
LDAILQRFAD CCRSLSSALS ECVVRGITVT TFGVDGALVD AQGKLLYPVI
110 120 130 140 150
SWKCPRTAAV METIERFISP RQLQTLSGVG AFSFNTLYKL VWLKENHPRL
160 170 180 190 200
LEQAHCWLFI SSLINHRLTG EFTTDITMAG TSQLLDIHQR DFSPEILQAT
210 220 230 240 250
GLARRLFPRI VEAGAPIGTL QTDAARLLGL PAGVPVISAE HDTQFALFGA
260 270 280 290 300
GAQQGEPVLS SGTWEILMVR SGQVDTSLLS QYPGSTCELD SQSGLYNPGM
310 320 330 340 350
QWLASGVLEW VRKLLWTPET PWQTLIDEAR AIPAGAEGVR MQCDLLACQN
360 370 380 390 400
AGWQGVTLNT TRGHFYRAAL EGLTAQLQRN LRTLEKIGHF NATELLLVGG
410 420 430 440 450
GSRNALWNQI KANQLDIPIK VLDDAETTVA GAAMFGWYGV GEFSSPEQAR
460 470
AQVNYQYRYF WPQTEPEIIE GV
Length:472
Mass (Da):51,746
Last modified:March 1, 2002 - v1
Checksum:i5CD73548EED519E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD02803.1.
AE014613 Genomic DNA. Translation: AAO70441.1.
RefSeqiNP_457372.1. NC_003198.1.

Genome annotation databases

EnsemblBacteriaiAAO70441; AAO70441; t2885.
CAD02803; CAD02803; CAD02803.
GeneIDi1249413.
KEGGisty:STY3117.
PATRICi18544286. VBISalEnt120419_3172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD02803.1.
AE014613 Genomic DNA. Translation: AAO70441.1.
RefSeqiNP_457372.1. NC_003198.1.

3D structure databases

ProteinModelPortaliQ8Z428.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi220341.STY3117.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO70441; AAO70441; t2885.
CAD02803; CAD02803; CAD02803.
GeneIDi1249413.
KEGGisty:STY3117.
PATRICi18544286. VBISalEnt120419_3172.

Phylogenomic databases

eggNOGiCOG1070.
HOGENOMiHOG000124178.
KOiK00879.
OMAiATNVRAM.
OrthoDBiEOG6X9MHN.

Enzyme and pathway databases

UniPathwayiUPA00563; UER00625.

Family and domain databases

HAMAPiMF_00986. Fuculokinase.
InterProiIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR013450. Fuculokinase.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000538. GlpK. 1 hit.
TIGRFAMsiTIGR02628. fuculo_kin_coli. 1 hit.
PROSITEiPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2.

Entry informationi

Entry nameiFUCK_SALTI
AccessioniPrimary (citable) accession number: Q8Z428
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2002
Last modified: June 24, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.