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Protein

Protein MgtC

Gene

mgtC

Organism
Salmonella typhi
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Virulence factor required for growth in low Mg2+ medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na+/K+-ATPase (By similarity).By similarity

GO - Biological processi

  • pathogenesis Source: CACAO

Keywordsi

Biological processVirulence

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MgtC
Gene namesi
Name:mgtC
Ordered Locus Names:STY4022, t3754
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000002670 Componenti: Chromosome
  • UP000000541 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei62 – 82HelicalSequence analysisAdd BLAST21
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002505291 – 231Protein MgtCAdd BLAST231

Interactioni

Protein-protein interaction databases

STRINGi220341.STY4022

Structurei

3D structure databases

ProteinModelPortaliQ8Z2J2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MgtC/SapB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105KT7 Bacteria
COG1285 LUCA
HOGENOMiHOG000080251
KOiK07507
OMAiHIRFLLM

Family and domain databases

InterProiView protein in InterPro
IPR003416 MgtC/SapB/SrpB/YhiD_fam
PANTHERiPTHR33778 PTHR33778, 1 hit
PfamiView protein in Pfam
PF02308 MgtC, 1 hit
PRINTSiPR01837 MGTCSAPBPROT

Sequencei

Sequence statusi: Complete.

Q8Z2J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEERMLMFPY ILNLLAAMLL GALIGAERQW RQRMAGLRTN ALVATGAAVF
60 70 80 90 100
ILSSMTTSPD SPGRIAAQIV SGIGFLGAGV IMREGMNVRG LNTAATLWCS
110 120 130 140 150
AGIGVLCGLG QFKNALAATI IILCANILLR EAAQRINQLP VSAEAEKRYI
160 170 180 190 200
LKVTCNKEDE SAVRQWLLNI VKEAAICLQG LGSVPAQEQG YKEIRAELVG
210 220 230
HADYRKTREL IISRIGDNDN ITAIHWSIDS Q
Length:231
Mass (Da):25,065
Last modified:March 1, 2002 - v1
Checksum:i398DCC35BB4E30FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA Translation: CAD03230.1
AE014613 Genomic DNA Translation: AAO71244.1
RefSeqiNP_458170.1, NC_003198.1
WP_000392697.1, NZ_PHKG01000002.1

Genome annotation databases

EnsemblBacteriaiAAO71244; AAO71244; t3754
CAD03230; CAD03230; CAD03230
GeneIDi1250261
KEGGistt:t3754
sty:STY4022
PATRICifig|220341.7.peg.4106

Similar proteinsi

Entry informationi

Entry nameiMGTC_SALTI
AccessioniPrimary (citable) accession number: Q8Z2J2
Secondary accession number(s): Q7C6D0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health