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Reviewed, UniProtKB/Swiss-Prot Q8Z2E0 (MTLD_SALTI)

Last modified February 9, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Mannitol-1-phosphate 5-dehydrogenase
    EC=1.1.1.17
Gene names
Name: mtlD
Ordered Locus Names: STY4110, t3833
OrganismSalmonella typhi [Complete proteome] [HAMAP]
Taxonomic identifier90370 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_0000170716

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Z2E0-1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: C562C574161443E1

FASTA38240,870
        10         20         30         40         50         60 
MKALHFGAGN IGRGFIGKLL ADAGIQLTFA DVNQVVLDAL NARHSYQVHV VGENEQVDTV 

        70         80         90        100        110        120 
SGVNAVSSIG DDVVDLIAHV DLITTAVGPV VLERIAPAIA KGLVKRKAQG VDAPLNIIAC 

       130        140        150        160        170        180 
ENMVRGTTQL KGHVMNALAD GDKAWVEQHV GFVDSAVDRI VPPSASATND PLEVTVETFS 

       190        200        210        220        230        240 
EWIVDKTQFK GALPNIPGME LTDNLMAFVE RKLFTLNTGH AITAYLGKLA GHQTIRDAIL 

       250        260        270        280        290        300 
DEGIRAVVKG AMEESGAVLI KRYGFDADKH AAYIQKILGR FENPYLKDDV ERVGRQPLRK 

       310        320        330        340        350        360 
LSAGDRLIKP LLGTLEYGLP HVNLVKGIAA AMHFRSDEDP QAQELAALIT EKGPQAALAQ 

       370        380 
ISGLDANSDV VAEAVNAYNA TK 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL627280 Genomic DNA. Translation: CAD03308.1.
AE014613 Genomic DNA. Translation: AAO71314.1.
RefSeqNP_458240.1.
NP_807454.1.

3D structure databases

SMRQ8Z2E0. Positions 2-359.
ModBaseSearch...

Genome annotation databases

GeneID1071231.
1250339.
GenomeReviewsGene locus t3833 in contig AE014613_GR.
KEGGstt:t3833.
sty:STY4110.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAVDRIVPN.

Enzyme and pathway databases

BioCycSENT209261:T3833-MONOMER.
SENT220341:STY4110-MONOMER.
BRENDA1.1.1.17. 3716.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR000669. Mannitol_DH_core.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_SALTI
AccessionPrimary (citable) accession number: Q8Z2E0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: March 1, 2002
Last modified: February 9, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents