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Q8Z289

- GUN_SALTI

UniProt

Q8Z289 - GUN_SALTI

Protein

Endoglucanase

Gene

bcsZ

Organism
Salmonella typhi
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Hydrolyzes carboxymethylcellulose.

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei56 – 561Proton donorBy similarity
    Active sitei117 – 1171NucleophilePROSITE-ProRule annotation

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    UniPathwayiUPA00694.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase (EC:3.2.1.4)
    Alternative name(s):
    Carboxymethylcellulase
    Short name:
    CMCase
    Cellulase
    Endo-1,4-beta-glucanase
    Gene namesi
    Name:bcsZ
    Ordered Locus Names:STY4183, t3900
    OrganismiSalmonella typhi
    Taxonomic identifieri90370 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000000541: Chromosome, UP000002670: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 369347EndoglucanasePRO_0000007940Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi220341.STY4183.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8Z289.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG3405.
    HOGENOMiHOG000259088.
    KOiK01179.
    OMAiDLWIAYT.
    OrthoDBiEOG6DG2PM.

    Family and domain databases

    Gene3Di1.50.10.10. 1 hit.
    InterProiIPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR002037. Glyco_hydro_8.
    IPR019834. Glyco_hydro_8_CS.
    [Graphical view]
    PfamiPF01270. Glyco_hydro_8. 1 hit.
    [Graphical view]
    PRINTSiPR00735. GLHYDRLASE8.
    SUPFAMiSSF48208. SSF48208. 1 hit.
    PROSITEiPS00812. GLYCOSYL_HYDROL_F8. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8Z289-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMTMLRGWIT MIVMLTAINA QAACSWPAWE QFKKDYISQQ GRVIDPGDAR    50
    KITTSEGQSY AMFFALAAND RPAFAQLFNW TQNNLAQGSL REHLPAWLWG 100
    QKDPDTWSVL DSNSASDGDI WMAWSLLEAG RLWKETRYTE VGTALLKRIA 150
    REEVVNVPGL GSMLLPGKIG FAEANSWRFN PSYLPPQLAQ YFSRFGAPWS 200
    TLRETNLRLL LETSPKGFSP DWVRYESKQG WQLKAEKTLI SSYDAIRVYL 250
    WTGMMHDGDP QKARLLARFK PMATLTMKNG VPPEKVDVVS GNAQGTGPVG 300
    FSAALLPFLQ NRGAQAVQRQ RVADHFPGSD AYYNYVLTLF GQGWDQHRFR 350
    FTVKGELLPD WGQECVSSR 369
    Length:369
    Mass (Da):41,703
    Last modified:March 1, 2002 - v1
    Checksum:i09954697C007F742
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL513382 Genomic DNA. Translation: CAD08008.1.
    AE014613 Genomic DNA. Translation: AAO71375.1.
    RefSeqiNP_458303.1. NC_003198.1.
    NP_807515.1. NC_004631.1.

    Genome annotation databases

    EnsemblBacteriaiAAO71375; AAO71375; t3900.
    CAD08008; CAD08008; CAD08008.
    GeneIDi1250407.
    KEGGisty:STY4183.
    PATRICi18546576. VBISalEnt120419_4272.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL513382 Genomic DNA. Translation: CAD08008.1 .
    AE014613 Genomic DNA. Translation: AAO71375.1 .
    RefSeqi NP_458303.1. NC_003198.1.
    NP_807515.1. NC_004631.1.

    3D structure databases

    ProteinModelPortali Q8Z289.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 220341.STY4183.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO71375 ; AAO71375 ; t3900 .
    CAD08008 ; CAD08008 ; CAD08008 .
    GeneIDi 1250407.
    KEGGi sty:STY4183.
    PATRICi 18546576. VBISalEnt120419_4272.

    Phylogenomic databases

    eggNOGi COG3405.
    HOGENOMi HOG000259088.
    KOi K01179.
    OMAi DLWIAYT.
    OrthoDBi EOG6DG2PM.

    Enzyme and pathway databases

    UniPathwayi UPA00694 .

    Family and domain databases

    Gene3Di 1.50.10.10. 1 hit.
    InterProi IPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR002037. Glyco_hydro_8.
    IPR019834. Glyco_hydro_8_CS.
    [Graphical view ]
    Pfami PF01270. Glyco_hydro_8. 1 hit.
    [Graphical view ]
    PRINTSi PR00735. GLHYDRLASE8.
    SUPFAMi SSF48208. SSF48208. 1 hit.
    PROSITEi PS00812. GLYCOSYL_HYDROL_F8. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CT18.
    2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
      Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
      J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700931 / Ty2.

    Entry informationi

    Entry nameiGUN_SALTI
    AccessioniPrimary (citable) accession number: Q8Z289
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 26, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3