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Q8Z289

- GUN_SALTI

UniProt

Q8Z289 - GUN_SALTI

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Protein

Endoglucanase

Gene

bcsZ

Organism
Salmonella typhi
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Hydrolyzes carboxymethylcellulose.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei56 – 561Proton donorBy similarity
Active sitei117 – 1171NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00694.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase (EC:3.2.1.4)
Alternative name(s):
Carboxymethylcellulase
Short name:
CMCase
Cellulase
Endo-1,4-beta-glucanase
Gene namesi
Name:bcsZ
Ordered Locus Names:STY4183, t3900
OrganismiSalmonella typhi
Taxonomic identifieri90370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000541: Chromosome, UP000002670: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 369347EndoglucanasePRO_0000007940Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi220341.STY4183.

Structurei

3D structure databases

ProteinModelPortaliQ8Z289.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3405.
HOGENOMiHOG000259088.
KOiK01179.
OMAiDLWIAYT.
OrthoDBiEOG6DG2PM.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR002037. Glyco_hydro_8.
IPR019834. Glyco_hydro_8_CS.
[Graphical view]
PfamiPF01270. Glyco_hydro_8. 1 hit.
[Graphical view]
PRINTSiPR00735. GLHYDRLASE8.
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00812. GLYCOSYL_HYDROL_F8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8Z289-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMTMLRGWIT MIVMLTAINA QAACSWPAWE QFKKDYISQQ GRVIDPGDAR
60 70 80 90 100
KITTSEGQSY AMFFALAAND RPAFAQLFNW TQNNLAQGSL REHLPAWLWG
110 120 130 140 150
QKDPDTWSVL DSNSASDGDI WMAWSLLEAG RLWKETRYTE VGTALLKRIA
160 170 180 190 200
REEVVNVPGL GSMLLPGKIG FAEANSWRFN PSYLPPQLAQ YFSRFGAPWS
210 220 230 240 250
TLRETNLRLL LETSPKGFSP DWVRYESKQG WQLKAEKTLI SSYDAIRVYL
260 270 280 290 300
WTGMMHDGDP QKARLLARFK PMATLTMKNG VPPEKVDVVS GNAQGTGPVG
310 320 330 340 350
FSAALLPFLQ NRGAQAVQRQ RVADHFPGSD AYYNYVLTLF GQGWDQHRFR
360
FTVKGELLPD WGQECVSSR
Length:369
Mass (Da):41,703
Last modified:March 1, 2002 - v1
Checksum:i09954697C007F742
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD08008.1.
AE014613 Genomic DNA. Translation: AAO71375.1.
RefSeqiNP_458303.1. NC_003198.1.
NP_807515.1. NC_004631.1.

Genome annotation databases

EnsemblBacteriaiAAO71375; AAO71375; t3900.
CAD08008; CAD08008; CAD08008.
GeneIDi1250407.
KEGGisty:STY4183.
PATRICi18546576. VBISalEnt120419_4272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513382 Genomic DNA. Translation: CAD08008.1 .
AE014613 Genomic DNA. Translation: AAO71375.1 .
RefSeqi NP_458303.1. NC_003198.1.
NP_807515.1. NC_004631.1.

3D structure databases

ProteinModelPortali Q8Z289.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 220341.STY4183.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO71375 ; AAO71375 ; t3900 .
CAD08008 ; CAD08008 ; CAD08008 .
GeneIDi 1250407.
KEGGi sty:STY4183.
PATRICi 18546576. VBISalEnt120419_4272.

Phylogenomic databases

eggNOGi COG3405.
HOGENOMi HOG000259088.
KOi K01179.
OMAi DLWIAYT.
OrthoDBi EOG6DG2PM.

Enzyme and pathway databases

UniPathwayi UPA00694 .

Family and domain databases

Gene3Di 1.50.10.10. 1 hit.
InterProi IPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR002037. Glyco_hydro_8.
IPR019834. Glyco_hydro_8_CS.
[Graphical view ]
Pfami PF01270. Glyco_hydro_8. 1 hit.
[Graphical view ]
PRINTSi PR00735. GLHYDRLASE8.
SUPFAMi SSF48208. SSF48208. 1 hit.
PROSITEi PS00812. GLYCOSYL_HYDROL_F8. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT18.
  2. "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18."
    Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.
    J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700931 / Ty2.

Entry informationi

Entry nameiGUN_SALTI
AccessioniPrimary (citable) accession number: Q8Z289
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3