Q8Z1U8 (Q8Z1U8_SALTI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartokinase RuleBase RU003448
EC=2.7.2.4 RuleBase RU003448

Gene names

Name:	lysC EMBL AAO71590.1
Ordered Locus Names:	STY4416 EMBL CAD09204.1, t4126 EMBL AAO71590.1

Organism

Salmonella typhi [Complete proteome] [HAMAP] EMBL CAD09204.1

Taxonomic identifier

90370 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate = ADP + 4-phospho-L-aspartate. RuleBase RU003448
Sequence similarities	Belongs to the aspartokinase family. RuleBase RU003448

Ontologies

Keywords
Molecular function	Kinase RuleBase RU003448 EMBL CAD09204.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro
Molecular_function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8Z1U8 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 2B485698881A09A8	FASTA	449	48,595
	10 20 30 40 50 60 MTEIVVSKFG GTSVADFDAM NRSADIVLSD ANVRLVVLSA SAGITNLLVA LAEGMEPGER 70 80 90 100 110 120 FATLDAIRKI QFDILDRLRH PNVIREEIER LLENITILAE AASLATSAAL TDELVSHGEL 130 140 150 160 170 180 MSTLLFVEIL RERDVQAHWF DVRKVMRTSD RFGRAEPDVA ALAELAAQQL LPRLSETLVI 190 200 210 220 230 240 TQGFIGSESK GRTTTLGRGG SDYTAALLAE ALHAARVDIW TDVPGIYTTD PRVVPVAQRI 250 260 270 280 290 300 DEIDFEEAAE MATFGAKVLH PATLLPAVRS DIPVFVGSSK DPQAGGTLVC NKTQNPPLFR 310 320 330 340 350 360 ALALRRNQTL LTLHSLNMLH SRGFLAEVFG ILARHNISVD LITTSEVSVA LTLDTTGSTS 370 380 390 400 410 420 TGDTLLTQSL LMELSALCRV EVEEGLALVA LIGNNLSKAC GVGKEVFGVL EPFNIRMICY 430 440 GASSHNLCFL VPGDDAEKVV QKLHQNLFE

References

[1]

"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18." Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P. , Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:848-852(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CT18 EMBL CAD09204.1.

[2]

"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18." Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. J. Bacteriol. 185:2330-2337(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700931 / Ty2 and Ty2 EMBL AAO71590.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014613 Genomic DNA. Translation: AAO71590.1. AL627282 Genomic DNA. Translation: CAD09204.1.
RefSeq	NP_807730.1. NC_004631.1.
3D structure databases
SMR	Q8Z1U8. Positions 3-449.
ModBase	Search...
Protein-protein interaction databases
STRING	220341.STY4416.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAO71590; AAO71590; t4126. CAD09204; CAD09204; CAD09204.
GeneID	1068481.
KEGG	stt:t4126.
PATRIC	18547073. VBISalEnt120419_4516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000293094.
KO	K00928.
OMA	IRLICYG.
ProtClustDB	PRK09084.
Family and domain databases
Gene3D	3.40.1160.10. 2 hits.
InterPro	IPR002912. ACT_dom. IPR001048. Asp/Glu/Uridylate_kinase. IPR005260. Asp_kin_monofn. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. [Graphical view]
Pfam	PF00696. AA_kinase. 1 hit. PF01842. ACT. 1 hit. [Graphical view]
PIRSF	PIRSF000726. Asp_kin. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00656. asp_kin_monofn. 1 hit. TIGR00657. asp_kinases. 1 hit.
PROSITE	PS00324. ASPARTOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8Z1U8_SALTI

Accession

Primary (citable) accession number: Q8Z1U8
Secondary accession number(s): Q7C5P6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)