Reviewed, UniProtKB/Swiss-Prot Q8Z0M3 (KAD2_ANASP)

Names and origin

Protein names

Recommended name:
    Probable adenylate kinase 2
      Short name=AK 2
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase 2

Gene names

Name:	adk2
Ordered Locus Names:	alr0068

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This small ubiquitous enzyme is essential for maintenance and cell growth. HAMAP MF_00235
Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00235
Subunit structure	Monomer By similarity. HAMAP MF_00235
Subcellular location	Cytoplasm By similarity HAMAP MF_00235.
Sequence similarities	Belongs to the adenylate kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 184	184	Probable adenylate kinase 2 HAMAP MF_00235		PRO_0000158717
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8Z0M3-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: FC942AA460626D78	FASTA	184	21,054
	10 20 30 40 50 60 MRLVILGGSG SGKSTQAQRL CSHLEITQIS TGEILREAIS HLSELGRHAQ PYMIKGELVP 70 80 90 100 110 120 DEMIIELIRL RLKKSDVIDG WVLEGYPRTA FQAEELDFLL DELGQKLDWA IYLQVPEAVM 130 140 150 160 170 180 VSRSLGRSLP DDQPEIVQRR VEIFYDRTVP ILEYYDRRRR LLTINGDQSP ELVLQSILKL LLVT

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB77592.1.
PIR	AD1815.
RefSeq	NP_484112.1.
3D structure databases
SMR	Q8Z0M3. Positions 1-181.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8Z0M3.
Genome annotation databases
GeneID	1103665.
GenomeReviews	Gene locus alr0068 in contig BA000019_GR.
KEGG	ana:alr0068.
NMPDR	fig|103690.1.peg.379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0563.
HOGENOM	HBG630208.
OMA	QNEVVLK.
Enzyme and pathway databases
BioCyc	NSP103690:ALR0068-MONOMER.
Family and domain databases
HAMAP	MF_00235. Adenylate_kinase_Adk. Divergent sequence. [Tree]
InterPro	IPR000850. Adenylate_kin. [Graphical view]
PANTHER	PTHR23359. Adenylate_kin. 1 hit.
Pfam	PF00406. ADK. 1 hit. [Graphical view]
PRINTS	PR00094. ADENYLTKNASE.
PROSITE	PS00113. ADENYLATE_KINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD2_ANASP

Accession

Primary (citable) accession number: Q8Z0M3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	March 1, 2002
Last modified:	January 19, 2010
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)