Reviewed, UniProtKB/Swiss-Prot Q8Z074 (PPNK2_ANASP)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 2
      Short name=Poly(P)/ATP NAD kinase 2
    EC=2.7.1.23

Gene names

Name:	ppnK2
Ordered Locus Names:	alr0227

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361		PRO_0000120589

Sequences

	Sequence		Length	Mass (Da)
	Q8Z074-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 92FF532C5F3D15A6	FASTA	306	33,933
	10 20 30 40 50 60 MQLKQVIIAY KARDSQSKRW AELCAKQLEN RNCQVLMGPS GPKDNPYPVF LASASQPIDL 70 80 90 100 110 120 AIVLGGDGTV LTSARHLAPA GIPILGVNVG GHLGFLTESV DEFQDTEKVW DRLFEDRYAI 130 140 150 160 170 180 QRRMMLQAAV YEGHRTNLEP VTERYLGLNE FCVKPASADR MITSILEMEI DGEVVDQYVG 190 200 210 220 230 240 DGLIISTPTG STGYTVSASG PIMHDGMEAI TITPICPMSL SSRPLILPAG SVVSIWPLGD 250 260 270 280 290 300 YDLSTKLWMD GVLATSIWPA HRVDIRMADC RAKFIVLREN NSYYQTLREK LLWAGTRVRY TSTQHN

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000019 Genomic DNA. Translation: BAB77751.1.
PIR	AC1835.
RefSeq	NP_484271.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q8Z074.
Genome annotation databases
GeneID	1103824.
GenomeReviews	Gene locus alr0227 in contig BA000019_GR.
KEGG	ana:alr0227.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8Z074.
OMA	KLHWAGS.
Enzyme and pathway databases
BioCyc	NSP103690:ALR0227-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK2_ANASP

Accession

Primary (citable) accession number: Q8Z074

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2002
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)