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Q8YY05 (G6PI_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:alr1050
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length528 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 528528Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180582

Sites

Active site3221Proton donor By similarity
Active site3511 By similarity
Active site4551 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YY05 [UniParc].

Last modified March 27, 2002. Version 1.
Checksum: 694C42CE28DEEBED

FASTA52857,819
        10         20         30         40         50         60 
MDAKALWQRY QEWLYFHEGL GLYLDVSRMR FDDAFVKSLL PKFDKAFADM AELEKGAIAN 

        70         80         90        100        110        120 
PDENRMVGHY WLRNPDLAPT PEIAQEIVQT LEQIEAFAEK IQTGAIHPPK ANRFTDIISI 

       130        140        150        160        170        180 
GIGGSALGPQ FVAEALAPEF PPLKIHFIDN TDPAGIDRIL THLRNHLAST LVLVISKSGG 

       190        200        210        220        230        240 
TPEPRNGMIE VKKAYAGQNL DFAQYAVAIT STGSNLDKVA QSEGWLATFP MYDWVGGRTS 

       250        260        270        280        290        300 
EMSSVGLVPA ALQGIDVRAM LEGAKEMDDA TRVPEVKNNP AALLALSWYY SGNGKGEKDM 

       310        320        330        340        350        360 
VVLPYKDSLL LFSRYLQQLV MESLGKEKDL DGNTVYQGIA VYGNKGSTDQ HAYVQQLREG 

       370        380        390        400        410        420 
VPNFFATLIE VLEDRHGASP EIDPGVTSGD YLSGFLLGTR QALYENQRDS ITVTIPQVNA 

       430        440        450        460        470        480 
RTVGALVALY ERTVGLYASL VNINAYHQPG VEAGKKAAAV ILDLQTKVVG LLQKEKTALS 

       490        500        510        520 
LEQIAEKIGA ADQVEAIYKI LRHLQANQRG VVFQGNLGQP SSLKISLS 

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000019 Genomic DNA. Translation: BAB73007.1.
PIRAG1937.
RefSeqNP_485093.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YY05.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING103690.alr1050.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB73007; BAB73007; BAB73007.
GeneID1104644.
KEGGana:alr1050.
PATRIC22772004. VBINosSp37423_1486.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMARQVGHYW.
OrthoDBEOG64R61J.
ProtClustDBPRK14096.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 2 hits.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_NOSS1
AccessionPrimary (citable) accession number: Q8YY05
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: March 27, 2002
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways