Q8YY05 (G6PI_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	alr1050

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	528 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 528	528	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000180582
Sites
	Active site	322	1	Proton donor By similarity
	Active site	351	1	By similarity
	Active site	455	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8YY05 [UniParc]. Last modified March 27, 2002. Version 1. Checksum: 694C42CE28DEEBED	FASTA	528	57,819
	10 20 30 40 50 60 MDAKALWQRY QEWLYFHEGL GLYLDVSRMR FDDAFVKSLL PKFDKAFADM AELEKGAIAN 70 80 90 100 110 120 PDENRMVGHY WLRNPDLAPT PEIAQEIVQT LEQIEAFAEK IQTGAIHPPK ANRFTDIISI 130 140 150 160 170 180 GIGGSALGPQ FVAEALAPEF PPLKIHFIDN TDPAGIDRIL THLRNHLAST LVLVISKSGG 190 200 210 220 230 240 TPEPRNGMIE VKKAYAGQNL DFAQYAVAIT STGSNLDKVA QSEGWLATFP MYDWVGGRTS 250 260 270 280 290 300 EMSSVGLVPA ALQGIDVRAM LEGAKEMDDA TRVPEVKNNP AALLALSWYY SGNGKGEKDM 310 320 330 340 350 360 VVLPYKDSLL LFSRYLQQLV MESLGKEKDL DGNTVYQGIA VYGNKGSTDQ HAYVQQLREG 370 380 390 400 410 420 VPNFFATLIE VLEDRHGASP EIDPGVTSGD YLSGFLLGTR QALYENQRDS ITVTIPQVNA 430 440 450 460 470 480 RTVGALVALY ERTVGLYASL VNINAYHQPG VEAGKKAAAV ILDLQTKVVG LLQKEKTALS 490 500 510 520 LEQIAEKIGA ADQVEAIYKI LRHLQANQRG VVFQGNLGQP SSLKISLS

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB73007.1.
PIR	AG1937.
RefSeq	NP_485093.1. NC_003272.1.
3D structure databases
ProteinModelPortal	Q8YY05.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YY05.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1104644.
GenomeReviews	Gene locus alr1050 in contig BA000019_GR.
KEGG	ana:alr1050.
NMPDR	fig|103690.1.peg.1360.
PATRIC	22772004. VBINosSp37423_1486.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0166.
HOGENOM	HBG285902.
OMA	RTSITSA.
PhylomeDB	Q8YY05.
ProtClustDB	PRK14096.
Enzyme and pathway databases
BioCyc	NSP103690:ALR1050-MONOMER.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
KO	K01810.
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 2 hits. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. False negative. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_NOSS1

Accession

Primary (citable) accession number: Q8YY05

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 27, 2002
Last sequence update:	March 27, 2002
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program