Q8YXQ7 (CARA_NOSS1) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 70.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Carbamoyl-phosphate synthase small chain EC=6.3.5.5 Alternative name(s): Carbamoyl-phosphate synthetase glutamine chain | ||||
| Gene names |
| ||||
| Organism | Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 103690 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc |
Protein attributes
| Sequence length | 388 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate. HAMAP MF_01209 |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1. HAMAP MF_01209 Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3. HAMAP MF_01209 |
| Subunit structure | Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate By similarity. |
| Sequence similarities | Belongs to the CarA family. Contains 1 glutamine amidotransferase type-1 domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis Pyrimidine biosynthesis |
| Domain | Glutamine amidotransferase |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW glutamine metabolic processInferred from electronic annotation. Source: UniProtKB-KW pyrimidine nucleotide biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW carbamoyl-phosphate synthase (glutamine-hydrolyzing) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 388 | 388 | Carbamoyl-phosphate synthase small chain HAMAP MF_01209 | PRO_0000112244 | |||||
Regions | |||||||||
| Domain | 196 – 382 | 187 | Glutamine amidotransferase type-1 | ||||||
| Region | 1 – 192 | 192 | CPSase HAMAP MF_01209 | ||||||
Sites | |||||||||
| Active site | 272 | 1 | Nucleophile By similarity | ||||||
| Active site | 355 | 1 | By similarity | ||||||
| Active site | 357 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. Tabata S.DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000019 Genomic DNA. Translation: BAB73112.1. |
| PIR | AH1950. |
| RefSeq | NP_485198.1. NC_003272.1. |
3D structure databases | |
| ProteinModelPortal | Q8YXQ7. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q8YXQ7. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1104749. |
| GenomeReviews | Gene locus alr1155 in contig BA000019_GR. |
| KEGG | ana:alr1155. |
| NMPDR | fig|103690.1.peg.1465. |
| PATRIC | 22772238. VBINosSp37423_1603. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0505. |
| HOGENOM | HBG286341. |
| OMA | FTYPELG. |
| PhylomeDB | Q8YXQ7. |
| ProtClustDB | PRK12564. |
Enzyme and pathway databases | |
| BioCyc | NSP103690:ALR1155-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01209. CPSase_S_chain. [Tree] |
| InterPro | IPR006274. CarbamoylP_synth_ssu. IPR002474. CarbamoylP_synth_ssu_N. IPR017926. GATASE_1. [Graphical view] |
| Gene3D | G3DSA:3.50.30.20. G3DSA:3.50.30.20. 1 hit. |
| KO | K01956. |
| Pfam | PF00988. CPSase_sm_chain. 1 hit. PF00117. GATase. 1 hit. [Graphical view] |
| SMART | SM01097. CPSase_sm_chain. 1 hit. [Graphical view] |
| SUPFAM | SSF52021. CP_synthsmall. 1 hit. |
| TIGRFAMs | TIGR01368. CPSaseIIsmall. 1 hit. |
| PROSITE | PS51273. GATASE_TYPE_1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CARA_NOSS1 | ||||||||
| Accession | Primary (citable) accession number: Q8YXQ7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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