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Reviewed, UniProtKB/Swiss-Prot Q8YX58 (HEM62_ANASP)

Last modified June 16, 2009. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic 2
      Short name=Coproporphyrinogenase 2
      Short name=Coprogen oxidase 2
    EC=1.3.3.3
Gene names
Name: hemF2
Ordered Locus Names: all1357
OrganismAnabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 347347Coproporphyrinogen-III oxidase, aerobic 2
PRO_0000109881

Sequences

Sequence LengthMass (Da)Tools
Q8YX58-1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 402D8DFB7BB51D29

FASTA34740,031
        10         20         30         40         50         60 
MGRHSDNSLQ ESANHTVLLT SPTNTIPKDS RQRSQQFMQN LQDEICTALE QLDGKASFHQ 

        70         80         90        100        110        120 
DHWERAEGGE GRTRVIREGR VFEQGGVNFS AVWGNSLPAS ILAQRPEAAG HEFFATGTSM 

       130        140        150        160        170        180 
VLHPRNPYVP TVHLNYRYFE AGPIWWFGGG ADLTPYYAFK EDAVHFHQTL KNACDVHNPE 

       190        200        210        220        230        240 
YYPTFKRWCD EYFYLRHREE QRGIGGIFFD YQDASGKLYV ESQTDSSVAI YSQKVGNVAR 

       250        260        270        280        290        300 
NWEDIFAFVQ SCGQAFLPAY LPIVERRQGI EYGDRQRNFQ LYRRGRYVEF NLVYDRGTVF 

       310        320        330        340 
GLQTKGRTES ILMSLPPLAR WEYCYEPEAG SPEAELTEVF LQPRDWV 

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

BA000019 Genomic DNA. Translation: BAB73314.1.
PIRAB1976.
RefSeqNP_485400.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1104952.
GenomeReviewsGene locus all1357 in contig BA000019_GR.
KEGGana:all1357.
NMPDRfig|103690.1.peg.1667.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ8YX58.
OMAQ8YX58. ETARWEY.

Enzyme and pathway databases

BioCycNSP103690:ALL1357-MON.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHEM62_ANASP
AccessionPrimary (citable) accession number: Q8YX58
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: March 1, 2002
Last modified: June 16, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents