ID   Q8YWB2_NOSS1            Unreviewed;       557 AA.
AC   Q8YWB2;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 112.
DE   SubName: Full=Two-component response regulator {ECO:0000313|EMBL:BAB78069.1};
GN   OrderedLocusNames=all1703 {ECO:0000313|EMBL:BAB78069.1};
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690 {ECO:0000313|EMBL:BAB78069.1, ECO:0000313|Proteomes:UP000002483};
RN   [1] {ECO:0000313|EMBL:BAB78069.1, ECO:0000313|Proteomes:UP000002483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576
RC   {ECO:0000313|Proteomes:UP000002483};
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000019; BAB78069.1; -; Genomic_DNA.
DR   PIR; AI2018; AI2018.
DR   RefSeq; WP_010995872.1; NZ_RSCN01000013.1.
DR   AlphaFoldDB; Q8YWB2; -.
DR   STRING; 103690.gene:10493721; -.
DR   KEGG; ana:all1703; -.
DR   eggNOG; COG2208; Bacteria.
DR   eggNOG; COG3437; Bacteria.
DR   OrthoDB; 109585at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd17569; REC_HupR-like; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 6.10.140.590; -; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002483};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          10..125
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   MOD_RES         59
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   557 AA;  62864 MW;  F21931381855FBC6 CRC64;
     MTETKVEKLK LMVVDDEPDN LDLLYRTFRR DFQVYKANHA RKALEILAQE GEMAVIISDQ
     RMPEMNGTEF LSLTVEKFPD TIRILLTGFT DVEDLVEAIN SGQVFKYITK PWNPERLKNL
     VEQATDTYRL VKKRTHELRR SLRRESLFNA VTTAIRESLD YESMLQKIAA TIGQTFEATC
     CLLKPVENNR LTANQFYYQN PAYNLPDSAF DPATLISQVL ETGHYQIAQE IYNDNPCNYL
     VVPLSYQQHL LAVLALYQWG REHPWQDEDI QLITGVAEQA ALAVSQAKLY QRLQEKQQQI
     SAELEVARQI QNNLLRQTLP DIKSAKLQAC CYPAREVGGD FFEIFVHPTK GDVWLAVGDV
     SGKGVPAALF MASAISVLRR ELAQEIPAEP NVVIHNLNHA LCDDLISNNC FITFVLARYT
     PTTRELVYAN AGHIYPLVWS NQIAPEKPNY LTVRGIPLGI LPKWQAKSGS LILAPGDTLL
     LASDGITEAM VSNSLLKQVK TVGGVQLASH SMLNQDGLWQ LLQQEPQPLS LNHLLSRIQA
     DNHIQEDDQT ILSLEVL
//