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Protein

Chaperone protein dnaK2

Gene

dnaK2

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein dnaK2
Alternative name(s):
HSP70-2
Heat shock 70 kDa protein 2
Heat shock protein 70-2
Gene namesi
Name:dnaK2
Ordered Locus Names:alr1742
OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 633633Chaperone protein dnaK2PRO_0000078408Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei197 – 1971Phosphothreonine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

Protein-protein interaction databases

STRINGi103690.alr1742.

Structurei

3D structure databases

ProteinModelPortaliQ8YW74.
SMRiQ8YW74. Positions 1-528.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228137.
KOiK04043.
OMAiERCLGPV.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YW74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVVGIDLG TTNSCVAVME GGKPTVIANA EGFRTTPSVV AFAKNGDTLV
60 70 80 90 100
GQIAKRQAVM NPENTFYSVK RFIGRRYDEV TNEATEVSYK VLSSGGNVKV
110 120 130 140 150
DSPGAGKQFA PEEISAKVLR KLVEDASKYL GETVTQAVIT VPAYFNDSQR
160 170 180 190 200
QATKDAGKIA GIEVMRIINE PTAASLAYGF DKKSNETILV FDLGGGTFDV
210 220 230 240 250
SVLEVGDGVF EVLATSGDTH LGGDDFDKKI VDFLAEQFRK DEGIDLRKDK
260 270 280 290 300
QALQRLTEAA EKAKIELSSV TQAEINLPFI TATQDGPKHL DMTLTRAKFE
310 320 330 340 350
ELCADLIDRC RIPVEQALRD AKLKKENIDE VVLVGGSTRI PAVQQLVKNL
360 370 380 390 400
LGREPNQTVN PDEVVAVGAA IQAGVLGGEV TGILLLDVTP LSLGVETLGG
410 420 430 440 450
VMTKIIPRNT TIPTKKSEVF STAVDGQTNV EIHVLQGERE FANDNKSLGT
460 470 480 490 500
FRLDGIPPAP RGVPQIEVVF DIDANGILNV TAKDKGTGKE QSISITGAST
510 520 530 540 550
LDKTDIDRMV REAEQNASSD KERREKIERK NQADSLAYQA EKQLQELGDK
560 570 580 590 600
VPEADKTKVE GLVKDLREAV AKEDDEQIKK LTPELQQALF AVGSNIYQQA
610 620 630
GGGAAPGAAP QDGGTTSSDG GDDVIDADFT ETK
Length:633
Mass (Da):67,908
Last modified:March 1, 2002 - v1
Checksum:iEC2BBE8662690BA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB73441.1.
PIRiAH2023.
RefSeqiWP_010995910.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB73441; BAB73441; BAB73441.
KEGGiana:alr1742.
PATRICi22773541. VBINosSp37423_2248.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB73441.1.
PIRiAH2023.
RefSeqiWP_010995910.1. NC_003272.1.

3D structure databases

ProteinModelPortaliQ8YW74.
SMRiQ8YW74. Positions 1-528.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi103690.alr1742.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB73441; BAB73441; BAB73441.
KEGGiana:alr1742.
PATRICi22773541. VBINosSp37423_2248.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228137.
KOiK04043.
OMAiERCLGPV.
OrthoDBiPOG091H01UE.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK2_NOSS1
AccessioniPrimary (citable) accession number: Q8YW74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.