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Q8YVX4

- TRMB_NOSS1

UniProt

Q8YVX4 - TRMB_NOSS1

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, alr1845
Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei47 – 471S-adenosyl-L-methionine By similarity
Binding sitei72 – 721S-adenosyl-L-methionine By similarity
Binding sitei99 – 991S-adenosyl-L-methionine By similarity
Active sitei125 – 1251 By similarity
Binding sitei125 – 1251S-adenosyl-L-methionine By similarity
Binding sitei129 – 1291Substrate By similarity
Binding sitei161 – 1611Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:alr1845
OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
ProteomesiUP000002483: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000171285Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi103690.alr1845.

Structurei

3D structure databases

ProteinModelPortaliQ8YVX4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000237936.
KOiK03439.
OMAiRVTIQFP.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YVX4-1 [UniParc]FASTAAdd to Basket

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MISGVSALPF VRVRQHVNPL AQKYLTPANP LEWEKAYSTP HQPLHLDIGC    50
ARGRFVLQMA QVEPNWNFLG LEIRESLVIE ANQFRSQLGL TNLHYLYCNA 100
NNSLQPLLSS LPTGILQRVT IQFPDPWFKT RHAKRRVVQP ELVQDIANYL 150
AVGGVVFLQS DMEFVAVEMC DRFAANPAFK KVGTGEWLTE NPLPVATERE 200
TTTQNRGEPV YRALFERSS 219
Length:219
Mass (Da):24,847
Last modified:March 1, 2002 - v1
Checksum:i6B255C82EA25C83C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000019 Genomic DNA. Translation: BAB73544.1.
PIRiAG2036.
RefSeqiNP_485885.1. NC_003272.1.
WP_010996013.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB73544; BAB73544; BAB73544.
GeneIDi1105437.
KEGGiana:alr1845.
PATRICi22773769. VBINosSp37423_2361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000019 Genomic DNA. Translation: BAB73544.1 .
PIRi AG2036.
RefSeqi NP_485885.1. NC_003272.1.
WP_010996013.1. NC_003272.1.

3D structure databases

ProteinModelPortali Q8YVX4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 103690.alr1845.

Protocols and materials databases

DNASUi 1105437.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB73544 ; BAB73544 ; BAB73544 .
GeneIDi 1105437.
KEGGi ana:alr1845.
PATRICi 22773769. VBINosSp37423_2361.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000237936.
KOi K03439.
OMAi RVTIQFP.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7120 / UTEX 2576.

Entry informationi

Entry nameiTRMB_NOSS1
AccessioniPrimary (citable) accession number: Q8YVX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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