Reviewed, UniProtKB/Swiss-Prot Q8YVS4 (GLMM_ANASP)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	alr1900

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 490	490	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147836
Sites
	Active site	139	1	Phosphoserine intermediate By similarity
	Metal binding	139	1	Magnesium; via phosphate group By similarity
	Metal binding	279	1	Magnesium By similarity
	Metal binding	281	1	Magnesium By similarity
	Metal binding	283	1	Magnesium By similarity
Amino acid modifications
	Modified residue	139	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8YVS4-1 [UniParc]. Last modified December 20, 2005. Version 2. Checksum: 5C3C4D375092B360	FASTA	490	52,509
	10 20 30 40 50 60 MVSSITRIQN YVIDGAATSN GLETVLESNF APSLISLPAT PLFGTDGIRG KVGELLSAPL 70 80 90 100 110 120 ALQIGFWAGV VLRNHADQLG PVILGQDSRN SSDMLAMALS AGLTAAGLEV WYLGLCPTPC 130 140 150 160 170 180 VAYLTSMSEA IGGVMISASH NPPEDNGIKI FGANGGKLSQ ALQAEIEKGL RGNLPITSNV 190 200 210 220 230 240 SNCGRHYSRW ELVKNYGEAL KRPWQNKVNL QGMKVVLDLA WGAAVGLAPS VFAEMGAEVI 250 260 270 280 290 300 SLHNAADGDR INVNCGSTHL EMLQAAVQEH NADLGFAFDG DADRVLAVDP TGRPVNGDYI 310 320 330 340 350 360 LYLWGLYLKQ QNQLPDNLIV STVMANLGFE KAWQQQGGKL IRTAVGDQYV QAEMIKTGAM 370 380 390 400 410 420 LGGEQSGHIL CSHYGMTGDG LLTALHLASL VKQSGVSLAE LIDQSFQTYP QLLRNVRVVD 430 440 450 460 470 480 RDRRLSWQNC TPVQQAIALA EKAMGDTGRI LVRASGTEPV IRVMVEAANA ELANYWTNEL 490 VAQVQQHLAP

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB73599.1. Different initiation.
PIR	AF2043.
RefSeq	NP_485940.1.
3D structure databases
SMR	Q8YVS4. Positions 41-489.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YVS4.
Genome annotation databases
GeneID	1105492.
GenomeReviews	Gene locus alr1900 in contig BA000019_GR.
KEGG	ana:alr1900.
NMPDR	fig|103690.1.peg.2207.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	VHDRYIE.
PhylomeDB	Q8YVS4.
Enzyme and pathway databases
BioCyc	NSP103690:ALR1900-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ANASP

Accession

Primary (citable) accession number: Q8YVS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	February 9, 2010
This is version 43 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)