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Q8YVQ0 (AROB_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:alr1924
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3633633-dehydroquinate synthase HAMAP MF_00110
PRO_0000140706

Sequences

Sequence LengthMass (Da)Tools
Q8YVQ0 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 88C8546056929D9C

FASTA36339,342
        10         20         30         40         50         60 
MTSVINVNLP TQSYEIAIAP ASLDQIGQSL AGLKLGKKVL LVSNPTIFKH FGKVAVDSLE 

        70         80         90        100        110        120 
AAGFQVASYS LPAGERYKTL NSIQKLYDIA LENRLERSST MVALGGGVIG DMTGFAAATW 

       130        140        150        160        170        180 
LRGINVVQVP TTLLAMVDSA IGGKTGVNHP HGKNLIGAFH QPRFVLIDPQ VLKTLPVREF 

       190        200        210        220        230        240 
RAGMAEVIKY GVIWDAELFN QLEQSKRLDQ LRYIKPELVD AILTRSCQAK ADVVGKDEKE 

       250        260        270        280        290        300 
GGLRAILNYG HTVGHAVESL TNYRLLKHGE AVGIGMVAAG QIAVNLELWQ QADADRQNAL 

       310        320        330        340        350        360 
IEKAGLPTKL PVGLDIEGII EALQLDKKVK DGKVRFVLPT QIGVVTVTDE VTSDHIRQVL 


QQM

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000019 Genomic DNA. Translation: BAB73623.1.
PIRAF2046.
RefSeqNP_485964.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YVQ0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8YVQ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1105516.
GenomeReviewsGene locus alr1924 in contig BA000019_GR.
KEGGana:alr1924.
NMPDRfig|103690.1.peg.2231.
PATRIC22773942. VBINosSp37423_2447.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ8YVQ0.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycNSP103690:ALR1924-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_NOSS1
AccessionPrimary (citable) accession number: Q8YVQ0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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