Q8YVJ2 (SYGA_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	all1985

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_0000072824

Sequences

	Sequence		Length	Mass (Da)
	Q8YVJ2 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: FBF8927F6658182D	FASTA	294	34,077
	10 20 30 40 50 60 MNFQSVIATL HQFWAERGCL IAQPYDIEKG AGTKNPHTFL RALGPEPWAV AYIEPCRRPT 70 80 90 100 110 120 DGRYGENPNR FQHYYQYQVL IKPSPDNIQD IYLDSLRALG IRPEDHDIRF VEDNWEDATV 130 140 150 160 170 180 GAWGTGWEVW LDGMEITQFT YFQQCGGIDC RPVSIEITYG LERLAMYLQE VEAITKIHWT 190 200 210 220 230 240 DDITYGDVFL QNEIEQSTYN FEASNPELLL TLFNLYEQEA SQLTERGLVL PSLDYVMKCS 250 260 270 280 290 HTFNLLDARG VISVTERTRY IARIRHLARK VANLYVEQRE KLGFPLLKNV PVAR

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB73684.1.
PIR	AC2054.
RefSeq	NP_486025.1. NC_003272.1.
3D structure databases
ProteinModelPortal	Q8YVJ2.
SMR	Q8YVJ2. Positions 1-277.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YVJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1105577.
GenomeReviews	Gene locus all1985 in contig BA000019_GR.
KEGG	ana:all1985.
NMPDR	fig|103690.1.peg.2292.
PATRIC	22774072. VBINosSp37423_2512.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	Q8YVJ2.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	NSP103690:ALL1985-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_NOSS1

Accession

Primary (citable) accession number: Q8YVJ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program