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Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.14UniRule annotation)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunitUniRule annotation
Short name:
GlyRSUniRule annotation
Gene namesi
Name:glyQUniRule annotation
Ordered Locus Names:all1985
OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 294294Glycine--tRNA ligase alpha subunitPRO_0000072824Add
BLAST

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi103690.all1985.

Structurei

3D structure databases

ProteinModelPortaliQ8YVJ2.
SMRiQ8YVJ2. Positions 1-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiPOG091H01SB.

Family and domain databases

CDDicd00733. GlyRS_alpha_core. 1 hit.
HAMAPiMF_00254. Gly_tRNA_synth_alpha. 1 hit.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YVJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFQSVIATL HQFWAERGCL IAQPYDIEKG AGTKNPHTFL RALGPEPWAV
60 70 80 90 100
AYIEPCRRPT DGRYGENPNR FQHYYQYQVL IKPSPDNIQD IYLDSLRALG
110 120 130 140 150
IRPEDHDIRF VEDNWEDATV GAWGTGWEVW LDGMEITQFT YFQQCGGIDC
160 170 180 190 200
RPVSIEITYG LERLAMYLQE VEAITKIHWT DDITYGDVFL QNEIEQSTYN
210 220 230 240 250
FEASNPELLL TLFNLYEQEA SQLTERGLVL PSLDYVMKCS HTFNLLDARG
260 270 280 290
VISVTERTRY IARIRHLARK VANLYVEQRE KLGFPLLKNV PVAR
Length:294
Mass (Da):34,077
Last modified:March 1, 2002 - v1
Checksum:iFBF8927F6658182D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB73684.1.
PIRiAC2054.
RefSeqiWP_010996147.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB73684; BAB73684; BAB73684.
KEGGiana:all1985.
PATRICi22774072. VBINosSp37423_2512.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB73684.1.
PIRiAC2054.
RefSeqiWP_010996147.1. NC_003272.1.

3D structure databases

ProteinModelPortaliQ8YVJ2.
SMRiQ8YVJ2. Positions 1-277.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi103690.all1985.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB73684; BAB73684; BAB73684.
KEGGiana:all1985.
PATRICi22774072. VBINosSp37423_2512.

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiPOG091H01SB.

Family and domain databases

CDDicd00733. GlyRS_alpha_core. 1 hit.
HAMAPiMF_00254. Gly_tRNA_synth_alpha. 1 hit.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYGA_NOSS1
AccessioniPrimary (citable) accession number: Q8YVJ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.