Alr2278 protein - Nostoc sp. (strain PCC 7120 / UTEX 2576)

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Q8YUQ7 (Q8YUQ7_NOSS1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 54. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Alr2278 protein EMBL BAB73977.1

Gene names

Ordered Locus Names:

alr2278 EMBL BAB73977.1

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP] EMBL BAB73977.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Heme PDB 2O09 PDB 2O0C PDB 2O0G Iron Metal-binding
Technical term	3D-structure PDB 2O09 PDB 2O0C PDB 2O0G PDB 3L6J PDB 3TF8 PDB 3TF9 PDB 3TFA PDB 3TFD PDB 3TFE PDB 3TFF PDB 3TFG Complete proteome
Gene Ontology (GO)
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

1

Iron (heme axial ligand); via tele nitrogen PDB 2O09 PDB 2O0C PDB 2O0G

Sequences

Sequence

Length

Mass (Da)

Tools

Q8YUQ7 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 34C54119F22AACC4
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189

21,192

        10         20         30         40         50         60 
MYGLVNKAIQ DMISKHHGED TWEAIKQKAG LEDIDFFVGM EAYSDDVTYH LVGAASEVLG 

        70         80         90        100        110        120 
KPAEELLIAF GEYWVTYTSE EGYGELLASA GDSLPEFMEN LDNLHARVGL SFPQLRPPAF 

       130        140        150        160        170        180 
ECQHTSSKSM ELHYQSTRCG LAPMVLGLLH GLGKRFQTKV EVTQTAFRET GEDHDIFSIK 


YEDSNLYDD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.
[2]	"NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism." Ma X., Sayed N., Beuve A., van den Akker F. EMBO J. 26:578-588(2007) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH HEME.
[3]	"Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase." Martin F., Baskaran P., Ma X., Dunten P.W., Schaefer M., Stasch J.P., Beuve A., van den Akker F. J. Biol. Chem. 285:22651-22657(2010) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
[4]	"Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain." Winter M.B., Herzik M.A., Kuriyan J., Marletta M.A. Proc. Natl. Acad. Sci. U.S.A. 108:E881-E889(2011) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BA000019 Genomic DNA. Translation: BAB73977.1.

PIR

RefSeq

NP_486318.1. NC_003272.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2O09	X-ray	2.10	A/B	1-189	[»]
2O0C	X-ray	2.60	A/B	1-189	[»]
2O0G	X-ray	2.51	A/B	1-189	[»]
3L6J	X-ray	2.30	A/B	1-189	[»]
3TF8	X-ray	2.13	A/B	1-189	[»]
3TF9	X-ray	2.59	A/B	1-189	[»]
3TFA	X-ray	2.27	A/B	1-189	[»]
3TFD	X-ray	1.96	A/B	1-189	[»]
3TFE	X-ray	1.99	A/B	1-189	[»]
3TFF	X-ray	1.94	A/B	1-189	[»]
3TFG	X-ray	1.90	A/B	1-189	[»]

ProteinModelPortal

SMR

Q8YUQ7. Positions 1-182.

ModBase

Protein-protein interaction databases

STRING

103690.alr2278.

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

BAB73977; BAB73977; BAB73977.

GeneID

KEGG

PATRIC

22774726. VBINosSp37423_2830.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

OMA

ProtClustDB

Family and domain databases

InterPro

IPR011644. Heme_NO-bd.
IPR024096. NO_sig/Golgi_transp_ligand-bd.
[Graphical view]

Pfam

PF07700. HNOB. 1 hit.
[Graphical view]

SUPFAM

SSF111126. Haem_NO-bd. 1 hit.

ProtoNet

Other

EvolutionaryTrace

Entry information

Entry name

Q8YUQ7_NOSS1

Accession

Primary (citable) accession number: Q8YUQ7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info