Q8YU00 (ACKA_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	all2561

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 405	405	Acetate kinase HAMAP MF_00020		PRO_0000107524

Sequences

	Sequence		Length	Mass (Da)
	Q8YU00 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: C9529CFFAC2BEE06	FASTA	405	43,937
	10 20 30 40 50 60 MKVLILNAGS SSQKSCLYEI PDDALLSEAP QPLWEGKVNW TQDRSVAEIE VKTARGETLH 70 80 90 100 110 120 ESIYGDSRQA HVTYMLYTLS RGATKVIGQL SEIDVVGHRV VHGGQNYRHS VIITEEVKQA 130 140 150 160 170 180 IAKLSNLAPA HNPAALEGIE AIEKSLGDVP QVAVFDTGFH ATLPDAAAIY PGPFEWVEQG 190 200 210 220 230 240 IRRYGFHGIS HQYCSARAAQ ILGRDLASLR IITCHLGNGC SLAAIKNGRS IDTTMGFTPL 250 260 270 280 290 300 DGLMMGSRSG AIDPGIIVHL MRQSDYSAER LDYVLNKASG LRGISGVSSD LPQVIEAITQ 310 320 330 340 350 360 GNYRAQLAWD MYVHRLRSGI GSMLASLGGL DVLVFTAGVG EKSAGIRQAA CEAFGFLGLK 370 380 390 400 LDPEKNQNKP VDIDIATADS TVRVLVIHTQ EDWAIAQQCW HLLKR

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB74260.1.
PIR	AB2126.
RefSeq	NP_486601.1. NC_003272.1.
3D structure databases
ProteinModelPortal	Q8YU00.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YU00.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1106158.
GenomeReviews	Gene locus all2561 in contig BA000019_GR.
KEGG	ana:all2561.
NMPDR	fig|103690.1.peg.2868.
PATRIC	22775330. VBINosSp37423_3130.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	WRYYAEL.
PhylomeDB	Q8YU00.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	NSP103690:ALL2561-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_NOSS1

Accession

Primary (citable) accession number: Q8YU00

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program