Q8YTZ5 (COMB_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	all2568

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081463

Sequences

	Sequence		Length	Mass (Da)
	Q8YTZ5 [UniParc]. Last modified March 27, 2002. Version 1. Checksum: BC7F48BA4E5B6958	FASTA	245	26,694
	10 20 30 40 50 60 MKLFVYHTPE LTPKDQVPDC AIAVDVLRAT STIATVLSAG GEAVQVFSDL DELIAVSEAW 70 80 90 100 110 120 PPQKRLRAGE RGGGKVTGFE LGNSPLDCTP ELVEGRRLFI STTNGTRALK RVQDSATVLT 130 140 150 160 170 180 AAFINRAAVV QYLLEKQPEI VWIVGSGWEG SYSLEDTACA GAIAHSVVEK SQLPPEELAG 190 200 210 220 230 240 NDEVISAIAL YSQWQNNLLG LFHHASHGKR LLRLECYEDL KYCSQTDVLT VLPIQQEAGV FKTKN

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB74267.1.
PIR	AI2126.
RefSeq	NP_486608.1. NC_003272.1.
3D structure databases
ProteinModelPortal	Q8YTZ5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YTZ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1106165.
GenomeReviews	Gene locus all2568 in contig BA000019_GR.
KEGG	ana:all2568.
NMPDR	fig|103690.1.peg.2875.
PATRIC	22775346. VBINosSp37423_3138.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	VMSTTNG.
PhylomeDB	Q8YTZ5.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	NSP103690:ALL2568-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_NOSS1

Accession

Primary (citable) accession number: Q8YTZ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 27, 2002
Last sequence update:	March 27, 2002
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program