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Protein

Glutaminase

Gene

glsA

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei76SubstrateUniRule annotation1
Binding sitei126SubstrateUniRule annotation1
Binding sitei170SubstrateUniRule annotation1
Binding sitei177SubstrateUniRule annotation1
Binding sitei201SubstrateUniRule annotation1
Binding sitei253SubstrateUniRule annotation1
Binding sitei271Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BRENDAi3.5.1.2. 319.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:all2934
OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001105871 – 334GlutaminaseAdd BLAST334

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi103690.all2934.

Structurei

3D structure databases

ProteinModelPortaliQ8YSZ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YSZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQANQGDL EIRPSPLLKV INDLHSKYKS LKEGIVANYI PELAKVNPDL
60 70 80 90 100
FSISIVTVDG QVYQVGDYQQ LFTIQSISKV FAYGLALEDH GRDYVLTRVG
110 120 130 140 150
VEPTGEAFNA IILDEQSKRP YNPMVNAGAI ATTSLIKGAG ATERLNRVLE
160 170 180 190 200
MFRRYIGHDV FVDISVFTSE RSTGHRNRAM AHLMLNFGMI DRNIEEALDL
210 220 230 240 250
YFQQCAVMVN CHDLAVMAAT LANRGVNPIT GEQAVNSRYI KDILSVMYTC
260 270 280 290 300
GMYNFAGEWA YKVGIPAKSG VCGGIMAVVP NLMGIAVFSP PLDIRGNSVR
310 320 330
GVKVCEELSQ QLGLHLFECM KVGNGEWGVG NCEC
Length:334
Mass (Da):36,712
Last modified:March 1, 2002 - v1
Checksum:iC802876E41928FBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB74633.1.
PIRiAG2172.
RefSeqiWP_010997085.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB74633; BAB74633; BAB74633.
KEGGiana:all2934.
PATRICi22776166. VBINosSp37423_3543.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB74633.1.
PIRiAG2172.
RefSeqiWP_010997085.1. NC_003272.1.

3D structure databases

ProteinModelPortaliQ8YSZ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi103690.all2934.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB74633; BAB74633; BAB74633.
KEGGiana:all2934.
PATRICi22776166. VBINosSp37423_3543.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.
OrthoDBiPOG091H02PU.

Enzyme and pathway databases

BRENDAi3.5.1.2. 319.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_NOSS1
AccessioniPrimary (citable) accession number: Q8YSZ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: September 7, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.