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Q8YSZ5

- GLSA_NOSS1

UniProt

Q8YSZ5 - GLSA_NOSS1

Protein

Glutaminase

Gene

glsA

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei76 – 761SubstrateUniRule annotation
    Binding sitei126 – 1261SubstrateUniRule annotation
    Binding sitei170 – 1701SubstrateUniRule annotation
    Binding sitei177 – 1771SubstrateUniRule annotation
    Binding sitei201 – 2011SubstrateUniRule annotation
    Binding sitei253 – 2531SubstrateUniRule annotation
    Binding sitei271 – 2711Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:all2934
    OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
    Taxonomic identifieri103690 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
    ProteomesiUP000002483: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 334334GlutaminasePRO_0000110587Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi103690.all2934.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YSZ5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OMAiNARADES.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8YSZ5-1 [UniParc]FASTAAdd to Basket

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    MSDQANQGDL EIRPSPLLKV INDLHSKYKS LKEGIVANYI PELAKVNPDL    50
    FSISIVTVDG QVYQVGDYQQ LFTIQSISKV FAYGLALEDH GRDYVLTRVG 100
    VEPTGEAFNA IILDEQSKRP YNPMVNAGAI ATTSLIKGAG ATERLNRVLE 150
    MFRRYIGHDV FVDISVFTSE RSTGHRNRAM AHLMLNFGMI DRNIEEALDL 200
    YFQQCAVMVN CHDLAVMAAT LANRGVNPIT GEQAVNSRYI KDILSVMYTC 250
    GMYNFAGEWA YKVGIPAKSG VCGGIMAVVP NLMGIAVFSP PLDIRGNSVR 300
    GVKVCEELSQ QLGLHLFECM KVGNGEWGVG NCEC 334
    Length:334
    Mass (Da):36,712
    Last modified:March 1, 2002 - v1
    Checksum:iC802876E41928FBF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000019 Genomic DNA. Translation: BAB74633.1.
    PIRiAG2172.
    RefSeqiNP_486974.1. NC_003272.1.
    WP_010997085.1. NC_003272.1.

    Genome annotation databases

    EnsemblBacteriaiBAB74633; BAB74633; BAB74633.
    GeneIDi1106532.
    KEGGiana:all2934.
    PATRICi22776166. VBINosSp37423_3543.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000019 Genomic DNA. Translation: BAB74633.1 .
    PIRi AG2172.
    RefSeqi NP_486974.1. NC_003272.1.
    WP_010997085.1. NC_003272.1.

    3D structure databases

    ProteinModelPortali Q8YSZ5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 103690.all2934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB74633 ; BAB74633 ; BAB74633 .
    GeneIDi 1106532.
    KEGGi ana:all2934.
    PATRICi 22776166. VBINosSp37423_3543.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OMAi NARADES.
    OrthoDBi EOG6N94BK.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 7120 / UTEX 2576.

    Entry informationi

    Entry nameiGLSA_NOSS1
    AccessioniPrimary (citable) accession number: Q8YSZ5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3