Q8YRT8 (NDHH_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NAD(P)H-quinone oxidoreductase subunit H
EC=1.6.5.-

Alternative name(s):
NAD(P)H dehydrogenase subunit H
NADH-plastoquinone oxidoreductase subunit H
NDH-1 subunit H
Short name=NDH-H

Gene names

Name:	ndhH
Ordered Locus Names:	alr3355

Organism

Nostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration By similarity. HAMAP MF_01358
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01358
Subunit structure	NDH-1 can be composed of about 15 different subunits; different subcomplexes with different compositions have been identified which probably have different functions By similarity.
Subcellular location	Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_01358.
Sequence similarities	Belongs to the complex I 49 kDa subunit family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane Thylakoid
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on NADH or NADPH Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	NAD(P)H-quinone oxidoreductase subunit H HAMAP MF_01358		PRO_0000118614

Sequences

	Sequence		Length	Mass (Da)
	Q8YRT8 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: EB08FD4AE90B617C	FASTA	394	45,216
	10 20 30 40 50 60 MARIETRTEP MVLNMGPHHP SMHGVLRLIV TLDGEDVVDC EPVIGYLHRG MEKIAENRTT 70 80 90 100 110 120 VMYVPYVSRW DYAAGMFNEA VTVNAPEKLA GVAVPKRASY IRVIMLELNR IANHLLWFGP 130 140 150 160 170 180 FLADVGAQTP FFYQFREREM IYDLWEAATG YRMVNNNYFR VGGVAADLPY GWVDKCLEFC 190 200 210 220 230 240 DYFLPVIDEY EKLVTNNPIF RRRIEGIGTI SREEAINWGL SGPMLRASGV KWDLRKVDHY 250 260 270 280 290 300 ECYDDFDWDV QWETAGDCLA RYTVRMREMR ESVKIIKQAI KGLPGGPYEN LEAKRLAAGK 310 320 330 340 350 360 KSEWDAFDYQ YIGKKVSPTF KMPKGEIYAR VESGKGELGI YLIGDDNVFP WRWKIRPADF 370 380 390 NNLQILPHLL RGMKVADVVV ILGSIDVIMG SVDR

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB75054.1.
PIR	AD2225.
RefSeq	NP_487395.1. NC_003272.1.
3D structure databases
ProteinModelPortal	Q8YRT8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YRT8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1106953.
GenomeReviews	Gene locus alr3355 in contig BA000019_GR.
KEGG	ana:alr3355.
NMPDR	fig|103690.1.peg.3662.
PATRIC	22777090. VBINosSp37423_4003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0649.
HOGENOM	HBG459705.
OMA	NWDLRKV.
PhylomeDB	Q8YRT8.
ProtClustDB	PRK07415.
Enzyme and pathway databases
BioCyc	NSP103690:ALR3355-MONOMER.
Family and domain databases
HAMAP	MF_01358. NDH1_NuoD. [Tree]
InterPro	IPR010219. NADH_DH_1_suD. IPR001135. NADH_Q_OxRdtase_suD. IPR014029. NADH_UbQ_OxRdtase_49kDa_CS. IPR022885. NDH1_su_D/H. [Graphical view]
KO	K05579.
Pfam	PF00346. Complex1_49kDa. 1 hit. [Graphical view]
TIGRFAMs	TIGR01962. NuoD. 1 hit.
PROSITE	PS00535. COMPLEX1_49K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDHH_NOSS1

Accession

Primary (citable) accession number: Q8YRT8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2003
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program