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Q8YRP3 (SPEA_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase
Short name=ADC
EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:all3401
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length679 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP MF_01417

Catalytic activity

L-arginine = agmatine + CO2. HAMAP MF_01417

Cofactor

Magnesium By similarity. HAMAP MF_01417

Pyridoxal phosphate By similarity. HAMAP MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 679679Biosynthetic arginine decarboxylase HAMAP MF_01417
PRO_0000149956

Regions

Region331 – 34111Substrate-binding Potential

Amino acid modifications

Modified residue1491N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YRP3 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 7A0AABEBB9FC6482

FASTA67976,821
        10         20         30         40         50         60 
MKHRGQEEMG VESTATSDEV VKVPANGNKL EGKNHKQKKL LPTNTPGDVS RVWKIEDSEA 

        70         80         90        100        110        120 
LYRIEGWGQP YFSINAAGHV TVSPKGDRGG SLDLFELVNA LKQRSLGLPL LIRFSDILED 

       130        140        150        160        170        180 
RIERLNACFA KAIARYNYPG VYRGVFPVKC NQQRHLIEDL VRFGRPHQFG LEAGSKPELM 

       190        200        210        220        230        240 
IALALLDTPG SLLICNGYKD REYVETAMLS QRLGQTPIIV LEQVEEVDLV IAASHQLGIK 

       250        260        270        280        290        300 
PILGVRAKLS TQGMGRWGTS TGDRAKFGLT IPEIIQAVDK LRDADLLDSL QLMHFHIGSQ 

       310        320        330        340        350        360 
ISAINVIKDA IQEASRIYVE LASLGANMKY LDVGGGLGVD YDGSQTNFYA SKNYNMQNYA 

       370        380        390        400        410        420 
NDIVAELKDT CAEKQIPVPT LISESGRAIA SHQSVLIFDV LSTSDVPRDN PEPPKEGESP 

       430        440        450        460        470        480 
VINYLWETYQ SINKENYQEF YHDATQFKEE AISRFNLGIL RLRERAKAER LYWACCQKIL 

       490        500        510        520        530        540 
DIIRQHDYVP DELEDLEKIM ASIYYINLSV FQSAPDCWAI DQLFPIMPIH RLDEEPTQRG 

       550        560        570        580        590        600 
ILADLTCDSD GKIDRFIDLR DVKSVLELHP FQPGEPYYMG MFLNGAYQEI MGNLHNLFGD 

       610        620        630        640        650        660 
TNAVHIQLTP KGYQIEHVVK GDTMSEVVSY VQYDSEDMVE NIRQRCERAL EEKRITLAES 

       670 
QRLLQTYEQS LRRYTYLNS

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References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000019 Genomic DNA. Translation: BAB75100.1.
PIRAB2231.
RefSeqNP_487441.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YRP3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8YRP3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1106999.
GenomeReviewsGene locus all3401 in contig BA000019_GR.
KEGGana:all3401.
NMPDRfig|103690.1.peg.3708.
PATRIC22777190. VBINosSp37423_4052.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHBG321436.
OMALICNGYK.
PhylomeDBQ8YRP3.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycNSP103690:ALL3401-MONOMER.

Family and domain databases

HAMAPMF_01417. SpeA.
[Tree]
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
KOK01585.
PANTHERPTHR11482:SF3. Arg_decrbxlase. 1 hit.
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR01273. SpeA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_NOSS1
AccessionPrimary (citable) accession number: Q8YRP3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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